scholarly journals Bioequivalence of Two Prolonged-Release Diclofenac Sodium Formulations in Healthy Volunteers: A Randomized, Crossover, Double-Blind Study

2017 ◽  
Vol 09 (06) ◽  
Author(s):  
Gonzalez Delgado CA ◽  
Padron Yaquis AS ◽  
Jimenez Rodriguez D ◽  
Cazanave Guarnaluce D ◽  
Alejo Cisneros PL ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Diclofenac Sodium ◽  
Blind Study ◽  
Prolonged Release ◽  
Double Blind Study ◽  
Double Blind

Pharmacological Modulation of Cutaneous Reactivity to Histamine: A Double-Blind Acute Comparative Study between Cetirizine, Terfenadine and Astemizole

1989 ◽  
Vol 17 (1) ◽  
pp. 24-27 ◽  
Author(s):  
L. Ghys ◽  
J.-P. Rihoux
Keyword(s):  
Comparative Study ◽  
Healthy Volunteers ◽  
Inhibitory Effect ◽  
Blind Study ◽  
Double Blind Study ◽  
Single Administration ◽  
Double Blind ◽  
Pharmacological Modulation ◽  
The Difference ◽  
Cutaneous Reactivity

In a double-blind study performed in 81 healthy volunteers, 10 mg cetirizine and 60 mg terfenadine given orally in a single administration significantly inhibited skin reactivity to histamine. Astemizole (10 mg) was completely ineffective. The inhibitory effect of cetirizine was potent and regular whereas 6/28 (21%) volunteers did not respond to terfenadine. The difference observed beween cetirizine and terfenadine might be due to differences in the metabolism of the two drugs after administration: terfenadine is rapidly and extensively metabolized whereas cetirizine is directly active without the need for biotransformation and, indeed is poorly metabolized.

Treatment of Acute Migraine Attack With Diclofenac Sodium: A Double-Blind Study

1992 ◽  
Vol 32 (2) ◽  
pp. 98-100 ◽  
Author(s):  
George N. Karachalios ◽  
Adroniki Fotiadou ◽  
Nickolaos Chrisikos ◽  
Alexandros Karabetsos ◽  
Kyriakos Kehagioglou
Keyword(s):  
Migraine Attack ◽  
Diclofenac Sodium ◽  
Blind Study ◽  
Double Blind Study ◽  
Acute Migraine ◽  
Double Blind ◽  
Acute Migraine Attack

scholarly journals The Effects of Mirtazapine on Sleep: A Placebo Controlled, Double-Blind Study in Young Healthy Volunteers

SLEEP ◽  
2002 ◽  
Vol 25 (6) ◽  
pp. 666-668 ◽  
Author(s):  
Selcuk Aslan ◽  
Erdal Isik ◽  
Behcet Cosar
Keyword(s):  
Healthy Volunteers ◽  
Blind Study ◽  
Double Blind Study ◽  
Double Blind

Effects of Neurexan ® in an experimental acute stress setting — An explorative double-blind study in healthy volunteers

Life Sciences ◽  
2016 ◽  
Vol 146 ◽  
pp. 139-147 ◽  
Author(s):  
B.K. Doering ◽  
A. Wegner ◽  
M. Hadamitzky ◽  
H. Engler ◽  
W. Rief ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Acute Stress ◽  
Blind Study ◽  
Double Blind Study ◽  
Double Blind
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