D, L-lysine acetylsalicylate + glycine Impairs Coronavirus Replication

2016 ◽  
Vol 08 (04) ◽  
Author(s):  
Christin Muller ◽  
Nadja Karl ◽  
John Ziebuhr ◽  
Stephan Pleschka
2021 ◽  
Vol 147 (2) ◽  
pp. AB159
Author(s):  
Meghan E. Robbins ◽  
Gloria Hwang ◽  
Jaqueline R. Hwang ◽  
Timothy Craig

Pain ◽  
2004 ◽  
Vol 111 (1) ◽  
pp. 191-200 ◽  
Author(s):  
Alejandro J. Pernia-Andrade ◽  
Victor Tortorici ◽  
Horacio Vanegas

2000 ◽  
Vol 18 (2) ◽  
pp. 185-200 ◽  
Author(s):  
Jean-Pierre Marissal ◽  
Bernard Selke ◽  
Th??r??se Lebrun

2009 ◽  
Vol 88 (04) ◽  
pp. 119-122
Author(s):  
L. Altomonte ◽  
A. Zoli ◽  
D. Accili ◽  
G. Ghirlanda ◽  
R. Manna ◽  
...  

1983 ◽  
Vol 245 (6) ◽  
pp. E591-E597 ◽  
Author(s):  
D. Giugliano ◽  
P. Di Pinto ◽  
R. Torella ◽  
N. Frascolla ◽  
F. Saccomanno ◽  
...  

These studies were undertaken to evaluate in humans the possible physiological role of prostaglandins of the E series (PGE) in modulating insulin release and to assess whether endogenous PGE synthesis may account for the biphasic pattern of insulin secretion. We used a square-wave glucose stimulation previously determined to give maximal biphasic insulin release. Infusion of lysine acetylsalicylate to block the synthesis of endogenous PGE increased by twofold total insulin response to glucose and also converted insulin release to a multiphasic pattern. The infusion of exogenous PGE1 (0.2 microgram X kg-1 X min-1) or PGE2 (10 micrograms/min) in addition to lysine acetylsalicylate restored the typical biphasic pattern of insulin release and also decreased total insulin release to values similar to those of control studies. Infusion of either PGE1 or PGE2 in the absence of lysine acetylsalicylate reset insulin secretion to a lower level without altering the kinetics of release. On the basis of these results, it is hypothesized that endogenous PGE released in response to glucose stimulation exert an inhibiting effect on insulin release that becomes biphasic in appearance.


The Lancet ◽  
1995 ◽  
Vol 346 (8980) ◽  
pp. 923-926 ◽  
Author(s):  
P Tfelt-Hansen ◽  
P Henry ◽  
L.J Mulder ◽  
R.G Scheldewaert ◽  
J Schoenen ◽  
...  

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