On a causal quantum stochastic double product integral related to Lévy area

2018 ◽  
Vol 5 (4) ◽  
pp. 467-512
Author(s):  
Robin Hudson ◽  
Yuchen Pei
Keyword(s):  
Double Product ◽  
Product Integral

scholarly journals Explicit construction of a unitary double product integral

2011 ◽  
Vol 96 ◽  
pp. 215-236
Author(s):  
R. L. Hudson ◽  
Paul Jones
Keyword(s):  
Explicit Construction ◽  
Double Product ◽  
Product Integral

The product integral

1991 ◽  
Vol 55 (5) ◽  
pp. 2042-2076 ◽  
Author(s):  
O. V. Manturov
Keyword(s):  
Product Integral

scholarly journals Impact of exercise based cardiac rehabilitation program in patients with transcatheter aortic valve replacement

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
LE Estrada Martinez ◽  
JA Lara Vargas ◽  
JA Pineda Juarez ◽  
JD Morales Portano ◽  
JB Gomez Alvarez ◽  
...  
Keyword(s):  
Heart Rate ◽  
Cardiac Rehabilitation ◽  
Intervention Group ◽  
Rehabilitation Program ◽  
Control Group ◽  
Cardiac Rehabilitation Program ◽  
Double Product ◽  
Oxygen Pulse ◽  
Transcatheter Aortic Valve ◽  
Cardiopulmonary Performance

Abstract Funding Acknowledgements Type of funding sources: None. Introduction  Due to the increase in global prevalence of degenerative valve disease, aortic stenosis (AS) has played a preponderant role in the cardiovascular scenario, especially in patients undergoing transcatheter aortic valve replacement (TAVR). An alternative management for this patients are the cardiac rehabilitation programs (CRP); however, their effect has not been completely understood, both in exercise capacity and quality of life, but neither in the improvement of cardiopulmonary performance and other cardiovascular outcomes.  Purpose: To evaluate the effect of the CRP on exercise tolerance and cardiopulmonary performance in patients with AS undergoing TAVR.  Methods: A cohort study was conducted including 26 patients with AS undergoing TAVR and divided into an intervention group who performed a 4-week supervised training program in the Cardiac Rehabilitation Service and a control group to whom instructions and recommendations to performed unsupervised exercise at home were given. Demographic and clinical data (VO2Max, METS12, oxygen pulse, heart rate, double product, left ventricular ejection fraction, body mass index) were collected at baseline and after a 4-week follow-up. Results: 15 patients were included in the intervention group and 11 patients in the control group. There were no baseline significant differences between groups. After the intervention, significant differences were observed in the METS 12 final gain variable between the control and intervention group (4.55 vs 3.1 p = 0.01). Intergroup analysis showed significant differences (percentage changes) in the intervention group with an increase of METS12 (67.4%, p = 0.001), oxygen pulse (18.21%, p = 0.01), final METS (39.47% p = 0.001) and a decrease in VO2 recovery time (-12.5%, p = 0.05), in the ergometric performance index by heart rate (-38.17%, p = 0.001) and by double product (-38.1%, p = 0.001). Conclusions  A 4-week cardiac rehabilitation program is effective to improve exercise tolerance and cardiopulmonary response in patients with AS undergoing TAVR; improvement was statistically significant in METS12, oxygen pulse, VO2 recovery time, METS-load and ergometric performance index for heart rate and double product. METS12 final gain was statistically significant in intervention group in comparison with the control group. Abstract Figure. Control vs Intervention Group (METS12)

Dobutamine as a countermeasure for reduced exercise performance of rats exposed to simulated microgravity

1997 ◽  
Vol 82 (5) ◽  
pp. 1607-1615 ◽  
Author(s):  
Charles M. Tipton ◽  
Lisa A. Sebastian
Keyword(s):  
Lactic Acid ◽  
Exercise Performance ◽  
Simulated Microgravity ◽  
Maximal Exercise ◽  
Blood Gases ◽  
Chronic Administration ◽  
Mechanical Efficiency ◽  
Male Rats ◽  
Double Product ◽  
Run Time

Tipton, Charles M., and Lisa A. Sebastian. Dobutamine as a countermeasure for reduced exercise performance of rats exposed to simulated microgravity. J. Appl. Physiol. 82(5): 1607–1615, 1997.—Post-spaceflight results and findings from humans and rodents after conditions of bed rest or simulated microgravity indicate maximum exercise performance is significantly compromised. However, the chronic administration of dobutamine (a synthetic adrenomimetic) to humans in relevant experiments improves exercise performance by mechanisms that prevent the decline in peak O2 consumption (V˙o 2 peak) and reduce the concentration of lactic acid measured in the blood. Although dobutamine restores maximumV˙o 2values in animals participating in simulated microgravity studies, it is unknown whether injections of this α1-, β1-, and β2-adrenoceptor agonist in rats will enhance exercise performance. To investigate this, adult male rats were assigned to three experimental groups: caged control receiving saline; head-down, tail-suspended (HDS) receiving saline (HDS-S); and an HDS group receiving dobutamine hydrochloride injections (1.8 mg/kg twice daily per rat). Treadmill tests were performed before suspension, at 14 days, and after 21 days.V˙o 2 peak, run time, and the rate of rise in colonic temperature (heating index) were evaluated after 14 days, whereas at 21 days, hemodynamic responses (heart rate, systolic blood pressure, and double product) were determined during submaximal exercise with blood pH, blood gases, and lactic acid concentration values obtained during maximal exercise. In contrast to the results for the HDS-S rats, dobutamine administration did restore V˙o 2 peakand “normalized” lactic acid concentrations during maximal exercise. However, daily injections were unable to enhance exercise performance aspects associated with treadmill run time, the mechanical efficiency of running, the heating index, or the retention of muscle and body mass. These simulated microgravity findings suggest that dobutamine’s potential value as a countermeasure for postflight maximal performance or for egress emergencies is limited and that other countermeasures must be considered.

Association between the anaerobic threshold and the break-point in the double product/work rate relationship

1996 ◽  
Vol 75 (1) ◽  
pp. 14-21 ◽  
Author(s):  
M. Riley ◽  
K. Maehara ◽  
J. P�rsz�sz ◽  
M. P. K. J. Engelen ◽  
H. Tanaka ◽  
...  
Keyword(s):  
Anaerobic Threshold ◽  
Break Point ◽  
Work Rate ◽  
Double Product ◽  
Rate Relationship

Abstract P028: Increased Cardiometabolic Risk And Autonomic Function Alterations In Normal Weight Obesity

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Alice P Duque ◽  
Isadora M Barbosa ◽  
Alessandra S Lins ◽  
Fernando G de Jesus ◽  
Christiane F Araújo ◽  
...  
Keyword(s):  
Body Fat ◽  
Cardiometabolic Risk ◽  
Autonomic Function ◽  
Normal Weight ◽  
Atherogenic Index ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Double Product ◽  
Visceral Fat Area ◽  
High Body

Introduction: Normal weight obesity (NWO) is defined by the presence of normal body mass index (BMI) with high body fat percentage. In this setting, high body fat seems to affect even non-obese individuals, predicting cardiovascular risk. Hypothesis: High body fat percentage, in eutrophic individuals, affects anthropometry, hemodynamic, autonomic function and cardiometabolic risk. Methods: This cross-sectional study recruited workers of a public hospital from 2018 to 2020. Inclusion criteria: age ≥ 18 yr.; BMI: 18.5 to 24.9 Kg/m 2 . Exclusion criteria: pregnancy/lactating women; BMI < 18.5 Kg/m 2 or ≥ 25 Kg/m 2 . High body fat percentage was categorized, by sex and age, as: 20 to 39 years, >19.9% and >32.9%; 40 to 59 years, >21.9% and >33.9%; and 60 to 79 years, >24.9% and >35.9% for men and women, respectively. Blood assays: fasting glucose, lipid profile and C reactive protein; anthropometry: neck, waist and hip circumferences; bioimpedance: visceral fat area and body fat percentage; hemodynamic parameters: blood pressure and double product; autonomic function: orthostatic test (30:15 ratio), orthostatic hypotension test and heart rate variability (HRV): high and low frequency and sympathovagal index; cardiometabolic risk: body shape index, atherogenic dyslipidemia, atherogenic index, atherogenic index of plasma and Framingham score. Statistical analysis: Mann-Whitney and chi-squared test. P<0.05. Ethics: according to Helsinki declaration, revised in 2013. Results: A total of 52 from 241 volunteers were eutrophic: 23 were NWO, that exhibited higher visceral fat area, anthropometric measures, blood pressure and double product; and worse lipid profile, HRV frequency domain and cardiometabolic risk parameters compared to the 29 with normal body fat percentage (table 1) . Conclusions: NWO individuals have metabolic, hemodynamic, anthropometric and autonomic alterations that, associated with new indexes related to atherogenesis, confirm the early cardiometabolic risk of this profile.

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