Preparation of Core Particles with High Drug Content from Slurry Materials using a Direct Granulation Method with a Fluidized Bed Granulator.

Hiroyuki TSUJIMOTO; Kazunori NAGATA; Toyokazu YOKOYAMA; Takayuki KAMATA; Keijirou TERASHITA; Kei MIYANAMI

doi:10.4164/sptj.37.107

Preparation of Core Particles with High Drug Content from Slurry Materials using a Direct Granulation Method with a Fluidized Bed Granulator.

Journal of the Society of Powder Technology Japan ◽

10.4164/sptj.37.107 ◽

2000 ◽

Vol 37 (2) ◽

pp. 107-114 ◽

Cited By ~ 3

Author(s):

Hiroyuki TSUJIMOTO ◽

Kazunori NAGATA ◽

Toyokazu YOKOYAMA ◽

Takayuki KAMATA ◽

Keijirou TERASHITA ◽

...

Keyword(s):

Fluidized Bed ◽

High Drug ◽

Drug Content ◽

Core Particles

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Glutathione-Sensitive Hyaluronic Acid-SS-Mertansine Prodrug with a High Drug Content: Facile Synthesis and Targeted Breast Tumor Therapy

Biomacromolecules ◽

10.1021/acs.biomac.6b01094 ◽

2016 ◽

Vol 17 (11) ◽

pp. 3602-3608 ◽

Cited By ~ 22

Author(s):

Ping Zhong ◽

Jian Zhang ◽

Chao Deng ◽

Ru Cheng ◽

Fenghua Meng ◽

...

Keyword(s):

Hyaluronic Acid ◽

Breast Tumor ◽

Tumor Therapy ◽

Facile Synthesis ◽

High Drug ◽

Drug Content

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Evolution of Granule Structure and Drug Content During Fluidized Bed Granulation by X-Ray Microtomography and Confocal Raman Spectroscopy

Journal of Pharmaceutical Sciences ◽

10.1002/jps.22719 ◽

2011 ◽

Vol 100 (12) ◽

pp. 5254-5269 ◽

Cited By ~ 14

Author(s):

Sami Poutiainen ◽

Jari Pajander ◽

Armi Savolainen ◽

Jarkko Ketolainen ◽

Kristiina Jarvinen

Keyword(s):

Raman Spectroscopy ◽

Fluidized Bed ◽

Confocal Raman Spectroscopy ◽

X Ray ◽

Drug Content ◽

Granule Structure ◽

Confocal Raman

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Facile preparation of pH/reduction dual-responsive prodrug microspheres with high drug content for tumor intracellular triggered release of DOX

Reactive and Functional Polymers ◽

10.1016/j.reactfunctpolym.2017.05.002 ◽

2017 ◽

Vol 116 ◽

pp. 24-30 ◽

Cited By ~ 9

Author(s):

Ruinian Zhang ◽

Xu Jia ◽

Mingliang Pei ◽

Peng Liu

Keyword(s):

Triggered Release ◽

High Drug ◽

Drug Content ◽

Dual Responsive ◽

Ph Reduction ◽

Facile Preparation

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Preparation and Evaluation of High Drug Content Particles

Drug Development and Industrial Pharmacy ◽

10.1081/ddc-120025868 ◽

2003 ◽

Vol 29 (10) ◽

pp. 1109-1118 ◽

Cited By ~ 8

Author(s):

Xiaoyan Wang ◽

Fude Cui ◽

Yorinobu Yonezawa ◽

Hisakazu Sunada

Keyword(s):

High Drug ◽

Drug Content ◽

Preparation And Evaluation

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One-Pot Synthesis of Chicken-Feather-Keratin-Based Prodrug Nanoparticles with High Drug Content for Tumor Intracellular DOX Delivery

Langmuir ◽

10.1021/acs.langmuir.9b01190 ◽

2019 ◽

Vol 35 (24) ◽

pp. 8007-8014 ◽

Cited By ~ 11

Author(s):

Huifang Zhang ◽

Peng Liu

Keyword(s):

Chicken Feather ◽

One Pot ◽

High Drug ◽

Feather Keratin ◽

Drug Content ◽

One Pot Synthesis

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Fully synthetic injectable depots with high drug content and tunable pharmacokinetics for long-acting drug delivery

Journal of Controlled Release ◽

10.1016/j.jconrel.2020.11.030 ◽

2021 ◽

Vol 329 ◽

pp. 257-269

Author(s):

Duy-Khiet Ho ◽

Clare LeGuyader ◽

Selvi Srinivasan ◽

Debashish Roy ◽

Vladimir Vlaskin ◽

...

Keyword(s):

Drug Delivery ◽

High Drug ◽

Drug Content ◽

Long Acting

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Granulation of Core Particles Suitable for Film Coating by Agitation Fluidized Bed III. Effect of Scale, Agitator Rotational Speed and Blade Shape on Granule Properties and Development of a High Accuracy Scale-Up Theory

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.57.325 ◽

2009 ◽

Vol 57 (4) ◽

pp. 325-331 ◽

Cited By ~ 2

Author(s):

Tomohiro Hamashita ◽

Tetsuo Ono ◽

Masaki Ono ◽

Yoshinobu Tsunenari ◽

Takao Aketo ◽

...

Keyword(s):

Fluidized Bed ◽

Rotational Speed ◽

Scale Up ◽

Film Coating ◽

High Accuracy ◽

Blade Shape ◽

Granule Properties ◽

Core Particles

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Development of a simple method for the preparation of a silica gel based controlled delivery system with a high drug content

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2005.05.002 ◽

2005 ◽

Vol 26 (1) ◽

pp. 87-96 ◽

Cited By ~ 22

Author(s):

Kotoe Machida Ohta ◽

Masayoshi Fuji ◽

Takashi Takei ◽

Masatoshi Chikazawa

Keyword(s):

Silica Gel ◽

Delivery System ◽

Controlled Delivery ◽

Simple Method ◽

High Drug ◽

Drug Content

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Granulation of Core Particles Suitable for Film Coating by Agitation Fluidized Bed I. Optimum Formulation for Core Particles and Development of a Novel Friability Test Method

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.55.1169 ◽

2007 ◽

Vol 55 (8) ◽

pp. 1169-1174 ◽

Cited By ~ 23

Author(s):

Tomohiro Hamashita ◽

Yasuo Nakagawa ◽

Takao Aketo ◽

Satoru Watano

Keyword(s):

Fluidized Bed ◽

Film Coating ◽

Test Method ◽

Optimum Formulation ◽

Core Particles

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Biomimetic pseudopolyrotaxane prodrug micelles with high drug content for intracellular drug delivery

Chemical Communications ◽

10.1039/c3cc43687j ◽

2013 ◽

Vol 49 (64) ◽

pp. 7123 ◽

Cited By ~ 51

Author(s):

Yin Wang ◽

Haibo Wang ◽

Yangjun Chen ◽

Xiangsheng Liu ◽

Qiao Jin ◽

...

Keyword(s):

Drug Delivery ◽

High Drug ◽

Drug Content ◽

Intracellular Drug Delivery

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