scholarly journals Elevated T-box 2 in infantile hemangioma stem cells maintains an adipogenic differentiation-competent state

2013 ◽  
Vol 5 (3) ◽  
pp. 352-357 ◽  
Author(s):  
Sydney M. Todorovich ◽  
Zia A. Khan
Keyword(s):  
Stem Cells ◽  
Adipogenic Differentiation ◽  
Infantile Hemangioma ◽  
T Box ◽  
Hemangioma Stem Cells

164: NOTCH3 KNOCKDOWN AFFECTS FUNCTIONAL BEHAVIOR OF INFANTILE HEMANGIOMA STEM CELLS

2011 ◽  
Vol 127 ◽  
pp. 90
Author(s):  
A Wong ◽  
O Adepoju ◽  
A Kitajewski ◽  
J Kitajewski ◽  
J Wu
Keyword(s):  
Stem Cells ◽  
Infantile Hemangioma ◽  
Functional Behavior ◽  
Hemangioma Stem Cells

Hemangioma Endothelial Cells and Hemangioma Stem Cells in Infantile Hemangioma

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Yuming Sun ◽  
Fengzhen Qiu ◽  
Chengjun Hu ◽  
Yu Guo ◽  
Shaorong Lei
Keyword(s):  
Stem Cells ◽  
Endothelial Cells ◽  
Infantile Hemangioma ◽  
Hemangioma Stem Cells

scholarly journals Isolation, characterization, and in vitro propagation of infantile hemangioma stem cells and an in vivo mouse model

2011 ◽  
Vol 4 (1) ◽  
pp. 54 ◽  
Author(s):  
Dan Xu ◽  
Teresa M O ◽  
Archil Shartava ◽  
Taylor C Fowles ◽  
Jianchang Yang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mouse Model ◽  
In Vitro Propagation ◽  
Infantile Hemangioma ◽  
Hemangioma Stem Cells

scholarly journals Notch pathway inhibitor DAPT accelerates in vitro proliferation and adipogenesis in infantile hemangioma stem cells

2021 ◽  
Vol 22 (6) ◽  
Author(s):  
Xing Xu ◽  
Yao Wu ◽  
Honghong Li ◽  
Juan Xie ◽  
Dongsheng Cao ◽  
...  
Keyword(s):  
Stem Cells ◽  
Notch Pathway ◽  
Infantile Hemangioma ◽  
In Vitro Proliferation ◽  
Hemangioma Stem Cells

scholarly journals Differentiation and Pro-Angiogenic Potential of Infantile Hemangioma Stem Cells

2020 ◽  
Vol 2 (1) ◽  
pp. 25-34
Author(s):  
Hanru YING ◽  
Qianyi CHEN ◽  
Xuanfeng CHEN ◽  
Zhang YU ◽  
Shih-Jen CHANG ◽  
...  
Keyword(s):  
Stem Cells ◽  
Infantile Hemangioma ◽  
Angiogenic Potential ◽  
Hemangioma Stem Cells

Differentiation of mesenchymal stem cells from humans and animals into insulin-producing cells: An overview in vitro induction forms

2020 ◽  
Vol 16 ◽  
Author(s):  
Bruna O. S. Câmara ◽  
Bruno M. Bertassoli ◽  
Natália M. Ocarino ◽  
Rogéria Serakides
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Culture Medium ◽  
Adipogenic Differentiation ◽  
Medium Composition ◽  
Cell Therapies ◽  
Insulin Producing Cells ◽  
Msc Differentiation

The use of stem cells in cell therapies has shown promising results in the treatment of several diseases, including diabetes mellitus, in both humans and animals. Mesenchymal stem cells (MSCs) can be isolated from various locations, including bone marrow, adipose tissues, synovia, muscles, dental pulp, umbilical cords, and the placenta. In vitro, by manipulating the composition of the culture medium or transfection, MSCs can differentiate into several cell lineages, including insulin-producing cells (IPCs). Unlike osteogenic, chondrogenic, and adipogenic differentiation, for which the culture medium and time are similar between studies, studies involving the induction of MSC differentiation in IPCs differ greatly. This divergence is usually evident in relation to the differentiation technique used, the composition of the culture medium, the cultivation time, which can vary from a few hours to several months, and the number of steps to complete differentiation. However, although there is no “gold standard” differentiation medium composition, most prominent studies mention the use of nicotinamide, exedin-4, ß-mercaptoethanol, fibroblast growth factor b (FGFb), and glucose in the culture medium to promote the differentiation of MSCs into IPCs. Therefore, the purpose of this review is to investigate the stages of MSC differentiation into IPCs both in vivo and in vitro, as well as address differentiation techniques and molecular actions and mechanisms by which some substances, such as nicotinamide, exedin-4, ßmercaptoethanol, FGFb, and glucose, participate in the differentiation process.

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