scholarly journals Mitotic Bypass Via An Occult Cell Cycle Phase Following DNA Topoisomerase II Inhibition In p53 Functional Human Tumor Cells

Cell Cycle ◽  
2007 ◽  
Vol 6 (16) ◽  
pp. 2071-2081 ◽  
Author(s):  
Paul J. Smith ◽  
Nuria Marquez ◽  
Marie Wiltshire ◽  
Sally Chappell ◽  
Kerenza Njoh ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Tumor Cells ◽  
Topoisomerase Ii ◽  
Human Tumor ◽  
Cell Cycle Phase ◽  
Cycle Phase ◽  
Dna Topoisomerase Ii ◽  
Human Tumor Cells ◽  
Dna Topoisomerase

scholarly journals The effects of proliferation status and cell cycle phase on the responses of single cells to chemotherapy

2020 ◽  
Vol 31 (8) ◽  
pp. 845-857 ◽  
Author(s):  
Adrián E. Granada ◽  
Alba Jiménez ◽  
Jacob Stewart-Ornstein ◽  
Nils Blüthgen ◽  
Simone Reber ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Information Theory ◽  
Tumor Cells ◽  
Single Cells ◽  
Residual Tumor ◽  
Cell Cycle Phase ◽  
Cycle Phase ◽  
Proliferating Cells ◽  
Probability Of Death

DNA-damaging chemotherapy often leaves residual tumor cells. Combining single-cell long-term live imaging with information theory, we found an unexpected effect: highly proliferative cells were more likely to arrest than to die, whereas more slowly proliferating cells showed a higher probability of death.

scholarly journals c-Myc depletion inhibits proliferation of human tumor cells at various stages of the cell cycle

Oncogene ◽  
2007 ◽  
Vol 27 (13) ◽  
pp. 1905-1915 ◽  
Author(s):  
H Wang ◽  
S Mannava ◽  
V Grachtchouk ◽  
D Zhuang ◽  
M S Soengas ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Tumor Cells ◽  
Human Tumor ◽  
Human Tumor Cells
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