scholarly journals Prolonged Mitosis Versus Tetraploid Checkpoint: How p53 Measures the Duration of Mitosis

Cell Cycle ◽  
2006 ◽  
Vol 5 (9) ◽  
pp. 971-975 ◽  
Author(s):  
Mikhail V. Blagosklonny
Keyword(s):  
Duration Of Mitosis

VARIATION IN THE DURATION OF MITOSIS IN THE CRYPTS OF LIEBERKUHN OF THE RAT; A CYTOKINETIC STUDY USING VINCRISTINE

1972 ◽  
Vol 5 (4) ◽  
pp. 351-364
Author(s):  
Nicholas Wright ◽  
Adrian Morley ◽  
David Appleton
Keyword(s):  
Duration Of Mitosis

DURATION OF MITOTIC CYCLE IN BRAIN CELLS OF THE MOSQUITO, AEDES DORSALIS

1969 ◽  
Vol 11 (3) ◽  
pp. 673-676 ◽  
Author(s):  
Asit B. Mukherjee ◽  
Don M. Rees
Keyword(s):  
Cell Cycle ◽  
High Resolution ◽  
Mitotic Cycle ◽  
Brain Cells ◽  
Duration Of Mitosis ◽  
High Resolution Autoradiography

Duration of the mitotic cycle and its various phases in the dividing brain cells of Aedes dorsalis larvae has been determined by high-resolution autoradiography. The length of the cell cycle is 10 hours. The duration of G1 is about 1 hour and 15 minutes, DNA synthetic period (S) is approximately 7 hours, G2 is 1 hour and the duration of mitosis (M) is about 45 minutes.

scholarly journals The duration of mitosis and daughter cell size are modulated by nutrients in budding yeast

2017 ◽  
Vol 216 (11) ◽  
pp. 3463-3470 ◽  
Author(s):  
Ricardo M. Leitao ◽  
Douglas R. Kellogg
Keyword(s):  
Cell Cycle ◽  
Cell Size ◽  
Daughter Cell ◽  
Slow Growth ◽  
Budding Yeast ◽  
Size Control ◽  
G1 Phase ◽  
Large Reduction ◽  
Duration Of Mitosis ◽  
Cell Cycle Entry

The size of nearly all cells is modulated by nutrients. Thus, cells growing in poor nutrients can be nearly half the size of cells in rich nutrients. In budding yeast, cell size is thought to be controlled almost entirely by a mechanism that delays cell cycle entry until sufficient growth has occurred in G1 phase. Here, we show that most growth of a new daughter cell occurs in mitosis. When the rate of growth is slowed by poor nutrients, the duration of mitosis is increased, which suggests that cells compensate for slow growth in mitosis by increasing the duration of growth. The amount of growth required to complete mitosis is reduced in poor nutrients, leading to a large reduction in cell size. Together, these observations suggest that mechanisms that control the extent of growth in mitosis play a major role in cell size control in budding yeast.

scholarly journals Studies on the Growth of Tissues In Vitro

1937 ◽  
Vol 14 (3) ◽  
pp. 255-266
Author(s):  
F. JACOBY ◽  
O. A. TROWELL ◽  
E. N. WILLMER
Keyword(s):  
Cell Division ◽  
Latent Period ◽  
Effective Dose ◽  
Appreciable Amount ◽  
Minimum Effective Dose ◽  
Tyrode Solution ◽  
Daughter Cells ◽  
Duration Of Mitosis ◽  
Division Process

1. Embryo juice initiates in cells growing in plasma alone a process which after a latent period of some 10-12 hours culminates in cell division, and it is not necessary for the embryo juice to be present in any appreciable amount during the actual division process. 2. The approximate minimum effective dose is 5 per cent embryo juice in Tyrode solution acting for 3 hours. 15 and 40 per cent juice produce marked effects when applied for only 1 hour. 3. The concentration of embryo juice is a more important factor in determining the number of mitoses produced than is the time for which it acts. 4. Unless the embryo juice remain in contact with the culture for more than 10 hours, only one crop of mitoses occurs; but if it is present in the medium during or after the occurrence of the first divisions, then a second crop of divisions takes place. Evidence is adduced that it is the daughter cells produced during the first crop of mitoses which divide to produce the second crop. 5. The duration of mitosis is correlated with the concentration of the embryo juice. It approaches a minimum of about 40 min. 6. The duration of mitosis, particularly that of the ana- and telophases, is correlated with the rate of migration of the cells. 7. When a second crop of mitoses occurs in these cultures which have passed through a period in plasma alone, there is evidence that the size of the cells in metaphase of mitosis is significantly less than that of the cells of the first crop.

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