scholarly journals Origin of DNA replication at the human lamin B2 locus: OBR or ABR?

Cell Cycle ◽  
2012 ◽  
Vol 11 (22) ◽  
pp. 4281-4283 ◽  
Author(s):  
Hoyun Lee ◽  
Julia Romero
BMC Biology ◽  
2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Eugene V. Koonin ◽  
Mart Krupovic ◽  
Sonoko Ishino ◽  
Yoshizumi Ishino

2005 ◽  
Vol 79 (13) ◽  
pp. 8661-8664 ◽  
Author(s):  
Stephen Schuck ◽  
Arne Stenlund

ABSTRACT Viral initiator proteins are polypeptides that form oligomeric complexes on the origin of DNA replication (ori). These complexes carry out a multitude of functions related to initiation of DNA replication, and although many of these functions have been characterized biochemically, little is understood about how the complexes are assembled. Here we demonstrate that loss of one particular interaction, the dimerization between E1 DNA binding domains, has a severe effect on DNA replication in vivo but has surprisingly modest effects on most individual biochemical activities in vitro. We conclude that the dimer interaction is primarily required for initial recognition of ori.


1987 ◽  
Vol 193 (3) ◽  
pp. 479-495 ◽  
Author(s):  
Michael P. Schmitt ◽  
Pamela J. Beck ◽  
Clare A. Kearney ◽  
Jean L. Spence ◽  
Donna DiGiovanni ◽  
...  

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