scholarly journals The prognostic significance of combined ERG and androgen receptor expression in patients with prostate cancer managed by androgen deprivation therapy

2014 ◽  
Vol 15 (9) ◽  
pp. 1120-1128 ◽  
Author(s):  
Kuo-Cheng Huang ◽  
Mohammed Alshalalfa ◽  
Samar A Hegazy ◽  
Michael Dolph ◽  
Bryan Donnelly ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Androgen Deprivation Therapy ◽  
Prognostic Significance ◽  
Androgen Deprivation ◽  
Receptor Expression ◽  
Androgen Receptor Expression

scholarly journals Next-generation androgen receptor inhibitors in non-metastatic castration-resistant prostate cancer

2020 ◽  
Vol 12 ◽  
pp. 175883592097813
Author(s):  
Pernelle Lavaud ◽  
Clément Dumont ◽  
Constance Thibault ◽  
Laurence Albiges ◽  
Giulia Baciarello ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Overall Survival ◽  
Androgen Receptor ◽  
Androgen Deprivation Therapy ◽  
Androgen Deprivation ◽  
Next Generation ◽  
Castration Resistant Prostate Cancer ◽  
Free Survival ◽  
Castration Resistant ◽  
Recent Advances

Until recently, continuing androgen deprivation therapy (ADT) and closely monitoring patients until evolution towards metastatic castration-resistant prostate cancer (CRPC) were recommended in men with non-metastatic CRPC (nmCRPC). Because delaying the development of metastases and symptoms in these patients is a major issue, several trials have investigated next-generation androgen receptor (AR) axis inhibitors such as apalutamide, darolutamide, and enzalutamide in this setting. This review summarizes the recent advances in the management of nmCRPC, highlighting the favourable impact of next-generation AR inhibitors on metastases-free survival, overall survival and other clinically meaningful endpoints.

scholarly journals Inhibiting Multiple Deubiquitinases to Reduce Androgen Receptor Expression in Prostate Cancer Cells

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Alicia de las Pozas ◽  
Teresita Reiner ◽  
Virginia De Cesare ◽  
Matthias Trost ◽  
Carlos Perez-Stable
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Cancer Cells ◽  
Receptor Expression ◽  
Androgen Receptor Expression ◽  
Prostate Cancer Cells

Pharmacological inhibition of androgen receptor expression induces cell death in prostate cancer cells

2020 ◽  
Vol 77 (22) ◽  
pp. 4663-4673 ◽  
Author(s):  
In-Sung Song ◽  
Yu Jeong Jeong ◽  
Jueun Kim ◽  
Kyoung-Hwa Seo ◽  
Nam-In Baek ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Death ◽  
Androgen Receptor ◽  
Cancer Cells ◽  
Receptor Expression ◽  
Androgen Receptor Expression ◽  
Prostate Cancer Cells ◽  
Pharmacological Inhibition
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