Development of a rat model of oral small molecule receptor tyrosine kinase inhibitor-induced diarrhea

Joanne M. Bowen; Bronwen J. Mayo; Erin Plews; Emma Bateman; Andrea M. Stringer; Frances M. Boyle; John W. Finnie; Dorothy M.K. Keefe

doi:10.4161/cbt.21783

Development of a rat model of oral small molecule receptor tyrosine kinase inhibitor-induced diarrhea

Cancer Biology & Therapy ◽

10.4161/cbt.21783 ◽

2012 ◽

Vol 13 (13) ◽

pp. 1269-1275 ◽

Cited By ~ 20

Author(s):

Joanne M. Bowen ◽

Bronwen J. Mayo ◽

Erin Plews ◽

Emma Bateman ◽

Andrea M. Stringer ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Small Molecule ◽

Rat Model ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Receptor Tyrosine Kinase Inhibitor

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Abstract 730: Efficacy of a novel small molecule MER receptor tyrosine kinase inhibitor in B-RAF wild-type and B-RAF mutant melanoma cell lines

10.1158/1538-7445.am2014-730 ◽

2014 ◽

Cited By ~ 1

Author(s):

Lenka S. Teodorovic ◽

Jacqueline Carrico ◽

Deborah DeRyckere ◽

Weihe Zhang ◽

Xiaodong Wang ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Cell Lines ◽

Small Molecule ◽

Melanoma Cell ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Wild Type ◽

Receptor Tyrosine Kinase Inhibitor ◽

Melanoma Cell Lines

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Sunitinib, a Small-Molecule Receptor Tyrosine Kinase Inhibitor, Suppresses Neointimal Hyperplasia in Balloon-Injured Rat Carotid Artery

Journal of Cardiovascular Pharmacology and Therapeutics ◽

10.1177/1074248412472258 ◽

2013 ◽

Vol 18 (4) ◽

pp. 359-366 ◽

Cited By ~ 8

Author(s):

So Ishii ◽

Yoshihisa Okamoto ◽

Harumi Katsumata ◽

Seiko Egawa ◽

Daisuke Yamanaka ◽

...

Keyword(s):

Carotid Artery ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Small Molecule ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Neointimal Hyperplasia ◽

Receptor Tyrosine Kinase Inhibitor

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Inhibition of Natural Type I IFN-Producing and Dendritic Cell Development by a Small Molecule Receptor Tyrosine Kinase Inhibitor with Flt3 Affinity

The Journal of Immunology ◽

10.4049/jimmunol.175.6.3674 ◽

2005 ◽

Vol 175 (6) ◽

pp. 3674-3680 ◽

Cited By ~ 40

Author(s):

Roxane Tussiwand ◽

Nobuyuki Onai ◽

Luca Mazzucchelli ◽

Markus G. Manz

Keyword(s):

Dendritic Cell ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Small Molecule ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Type I ◽

Type I Ifn ◽

Receptor Tyrosine Kinase Inhibitor ◽

Natural Type

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Sunitinib (Sutent, SU11248), a Small-Molecule Receptor Tyrosine Kinase Inhibitor, Blocks Function of the ATP-Binding Cassette (ABC) Transporters P-Glycoprotein (ABCB1) and ABCG2

Drug Metabolism and Disposition ◽

10.1124/dmd.108.024612 ◽

2008 ◽

Vol 37 (2) ◽

pp. 359-365 ◽

Cited By ~ 151

Author(s):

Suneet Shukla ◽

Robert W. Robey ◽

Susan E. Bates ◽

Suresh V. Ambudkar

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Small Molecule ◽

Receptor Tyrosine Kinase ◽

Abc Transporters ◽

Kinase Inhibitor ◽

Atp Binding ◽

Receptor Tyrosine Kinase Inhibitor ◽

P Glycoprotein ◽

Atp Binding Cassette

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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

10.32388/jfobd7 ◽

2020 ◽

Author(s):

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Receptor Tyrosine Kinase Inhibitor ◽

Epidermal Growth

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Delayed Therapy with Receptor Tyrosine Kinase Inhibitor Nintedanib Diminished Chronic Rejection in a Murine Lung Transplant Model

10.1055/s-0041-1725623 ◽

2021 ◽

Author(s):

J. Mauer ◽

A. Kuckhahn ◽

J. Distler ◽

B. Spriewald ◽

M. Ramsperger-Gleixner ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Receptor Tyrosine Kinase ◽

Chronic Rejection ◽

Lung Transplant ◽

Kinase Inhibitor ◽

Murine Lung ◽

Receptor Tyrosine Kinase Inhibitor ◽

Transplant Model

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Everolimus zur Behandlung des metastasierten Nierenzellkarzinoms nach Versagen der ersten VEGFr-TKI(Vascular Endothelial Growth Factor Receptor-Tyrosine Kinase Inhibitor)-Therapie: Ergebnisse einer Interimsanalyse einer nichtinterventionellen Studie

Karger Kompass Onkologie ◽

10.1159/000356898 ◽

2014 ◽

Vol 1 (1) ◽

pp. 28-29

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Vascular Endothelial ◽

Receptor Tyrosine Kinase Inhibitor ◽

Endothelial Growth Factor

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Glomerular Changes in Rats Administered ABT-869, a Multitargeted Receptor Tyrosine Kinase Inhibitor - Linking Ultrastructure to Mechanism

Microscopy and Microanalysis ◽

10.1017/s1431927609097566 ◽

2009 ◽

Vol 15 (S2) ◽

pp. 16-17

Author(s):

J Fagerland ◽

S Morgan

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Receptor Tyrosine Kinase Inhibitor

Extended abstract of a paper presented at Microscopy and Microanalysis 2009 in Richmond, Virginia, USA, July 26 – July 30, 2009

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The effect of combination treatment with gemcitabine and the EGFR-receptor tyrosine kinase inhibitor iressa with photodynamic therapy in bladder cancer

European Urology Supplements ◽

10.1016/s1569-9056(03)80175-6 ◽

2003 ◽

Vol 2 (1) ◽

pp. 44

Author(s):

C.H. Briggs ◽

C.D. Betts ◽

K.J. O'Flynn ◽

J.V. Moore ◽

N.W. Clarke

Keyword(s):

Bladder Cancer ◽

Photodynamic Therapy ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Combination Treatment ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Receptor Tyrosine Kinase Inhibitor

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172 Preclinical profile of ABP309, a potent 2nd generation VEGF receptor tyrosine kinase inhibitor belonging to the class of aminonicotinamides

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(04)80180-0 ◽

2004 ◽

Vol 2 (8) ◽

pp. 54-55

Author(s):

J. Brueggen ◽

G. Bold ◽

R. Cozens ◽

P.W. Manley ◽

J. Mestan ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Vegf Receptor ◽

Receptor Tyrosine Kinase Inhibitor ◽

2Nd Generation

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