scholarly journals Integrin linked kinase (ILK) expression and function in vascular smooth muscle cells

2009 ◽  
Vol 3 (2) ◽  
pp. 174-176 ◽  
Author(s):  
Bernard Ho ◽  
Michelle P. Bendeck
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Muscle Cells ◽  
Integrin Linked Kinase ◽  
And Function

Expression and function of periostin-like factor in vascular smooth muscle cells

2007 ◽  
Vol 292 (5) ◽  
pp. C1672-C1680 ◽  
Author(s):  
Judith Litvin ◽  
Xing Chen ◽  
Sheri Keleman ◽  
Shimei Zhu ◽  
Michael Autieri
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Clinical Manifestations ◽  
Muscle Cells ◽  
Antibody Treatment ◽  
The Media ◽  
Vascular Proliferative Diseases ◽  
And Function

In injured blood vessels activated vascular smooth muscle cells (VSMCs) migrate from the media to the intima, proliferate and synthesize matrix proteins. This results in occlusion of the lumen and detrimental clinical manifestations. We have identified a novel isoform of the periostin family of proteins referred to as periostin-like factor (PLF). PLF expression in VSMCs was increased following treatment with mitogenic compounds, suggesting that PLF plays a role in VSMC activation. Correspondingly, proliferation of the cells was significantly reduced with anti-PLF antibody treatment. PLF expression increased VSMC migration, an essential cellular process leading to vascular restenosis after injury. PLF protein was localized to neointimal VSMC of rat and swine balloon angioplasty injured arteries, as well as in human arteries with transplant restenosis, supporting the hypothesis that PLF is involved in VSMC activation and vascular proliferative diseases. Taken together, these data suggest a role for PLF in the regulation of vascular proliferative disease.

scholarly journals Data in support of alpha1beta1 and integrin-linked kinase interact and modulate angiotensin II effects in vascular smooth muscle cells

Data in Brief ◽  
2016 ◽  
Vol 6 ◽  
pp. 330-340 ◽  
Author(s):  
João Alfredo Moraes ◽  
Ana Clara Frony ◽  
Aline Maria Dias ◽  
Mariana Renovato-Martins ◽  
Genilson Rodrigues ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Angiotensin Ii ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Muscle Cells ◽  
Integrin Linked Kinase

scholarly journals Orai1 expression and function in vascular smooth muscle cells

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Jing Li ◽  
Amit Jairaman ◽  
Piruthivi Sukumar ◽  
Karen Porter ◽  
David Beech
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Muscle Cells ◽  
And Function

scholarly journals Alpha1beta1 and integrin-linked kinase interact and modulate angiotensin II effects in vascular smooth muscle cells

2015 ◽  
Vol 243 (2) ◽  
pp. 477-485 ◽  
Author(s):  
João Alfredo Moraes ◽  
Ana Clara Frony ◽  
Aline Maria Dias ◽  
Mariana Renovato-Martins ◽  
Genilson Rodrigues ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Angiotensin Ii ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Muscle Cells ◽  
Integrin Linked Kinase

Role of integrin-linked kinase in vascular smooth muscle cells: Regulation by statins and angiotensin II

2006 ◽  
Vol 349 (3) ◽  
pp. 883-889 ◽  
Author(s):  
Erik B. Friedrich ◽  
Yvonne P. Clever ◽  
Sven Wassmann ◽  
Nikos Werner ◽  
Michael Böhm ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Angiotensin Ii ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Muscle Cells ◽  
Integrin Linked Kinase

scholarly journals Aortic Aneurysm Generation in Mice With Targeted Deletion of Integrin-Linked Kinase in Vascular Smooth Muscle Cells

2011 ◽  
Vol 109 (6) ◽  
pp. 616-628 ◽  
Author(s):  
Dongxiao Shen ◽  
Jian Li ◽  
John J. Lepore ◽  
Thomas J.T. Anderson ◽  
Sumita Sinha ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Aortic Aneurysm ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Muscle Cells ◽  
Targeted Deletion ◽  
Integrin Linked Kinase

S1P receptor signalling and RGS proteins; expression and function in vascular smooth muscle cells and transfected CHO cells

2008 ◽  
Vol 600 (1-3) ◽  
pp. 1-9 ◽  
Author(s):  
Mariëlle C. Hendriks-Balk ◽  
Pieter B. van Loenen ◽  
Najat Hajji ◽  
Martin C. Michel ◽  
Stephan L.M. Peters ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Cho Cells ◽  
Muscle Cells ◽  
Rgs Proteins ◽  
Receptor Signalling ◽  
S1p Receptor ◽  
And Function

Inflammatory cytokines stimulate vascular smooth muscle cells locomotion and growth by enhancing α5β1 integrin expression and function

2001 ◽  
Vol 154 (2) ◽  
pp. 377-385 ◽  
Author(s):  
Giovanni Barillari ◽  
Loredana Albonici ◽  
Sandra Incerpi ◽  
Laura Bogetto ◽  
Giuseppa Pistritto ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Inflammatory Cytokines ◽  
Vascular Smooth Muscle Cells ◽  
Muscle Cells ◽  
Integrin Expression ◽  
And Function ◽  
Α5β1 Integrin
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