scholarly journals Erratum to: Huang Q, Shen H-M. To die or to live: The dual role of poly(ADP-ribose) polymerase-1 in autophagy and necrosis under oxidative stress and DNA damage. Autophagy 2009; 5:273–6

Autophagy ◽  
2010 ◽  
Vol 6 (8) ◽  
pp. 1232-1232 ◽  
Author(s):  
Han-Ming Shen ◽  
Qing Huang
Keyword(s):  
Oxidative Stress ◽  
Dna Damage ◽  
Dual Role

scholarly journals Role of histone deacetylase 2 in epigenetics and cellular senescence: implications in lung inflammaging and COPD

2012 ◽  
Vol 303 (7) ◽  
pp. L557-L566 ◽  
Author(s):  
Hongwei Yao ◽  
Irfan Rahman
Keyword(s):  
Oxidative Stress ◽  
Dna Damage ◽  
Histone Deacetylase ◽  
Dna Damage Response ◽  
Cellular Senescence ◽  
Premature Aging ◽  
Epigenetic Mechanism ◽  
Histone Deacetylase 2 ◽  
Damage Response

Histone deacetylase 2 (HDAC2) is a class I histone deacetylase that regulates various cellular processes, such as cell cycle, senescence, proliferation, differentiation, development, apoptosis, and glucocorticoid function in inhibiting inflammatory response. HDAC2 has been shown to protect against DNA damage response and cellular senescence/premature aging via an epigenetic mechanism in response to oxidative stress. These phenomena are observed in patients with chronic obstructive pulmonary disease (COPD). HDAC2 is posttranslationally modified by oxidative/carbonyl stress imposed by cigarette smoke and oxidants, leading to its reduction via an ubiquitination-proteasome dependent degradation in lungs of patients with COPD. In this perspective, we have discussed the role of HDAC2 posttranslational modifications and its role in regulation of inflammation, histone/DNA epigenetic modifications, DNA damage response, and cellular senescence, particularly in inflammaging, and during the development of COPD. We have also discussed the potential directions for future translational research avenues in modulating lung inflammaging and cellular senescence based on epigenetic chromatin modifications in diseases associated with increased oxidative stress.

The role of melatonin in oxidative stress, DNA damage, apoptosis and angiogenesis in fetal eye under preeclampsia and melatonin deficiency stress

2019 ◽  
Author(s):  
Zeynep Banu Doganlar ◽  
Hande Güçlü ◽  
Özlem Öztopuz ◽  
Hakan Türkön ◽  
Ayten Dogan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Dna Damage

Protective role of chrysin on doxorubicin‐induced oxidative stress and DNA damage in rat testes

Andrologia ◽  
2020 ◽  
Vol 52 (9) ◽  
Author(s):  
Saadet Belhan ◽  
Mustafa Özkaraca ◽  
Uğur Özdek ◽  
Ahmet Ufuk Kömüroğlu
Keyword(s):  
Oxidative Stress ◽  
Dna Damage ◽  
Protective Role

scholarly journals A dual role of Cdk2 in DNA damage response

Cell Division ◽  
2009 ◽  
Vol 4 (1) ◽  
pp. 9 ◽  
Author(s):  
Ande Satyanarayana ◽  
Philipp Kaldis
Keyword(s):  
Dna Damage ◽  
Dna Damage Response ◽  
Dual Role ◽  
Damage Response

Dual role of vitamin C in an oxygen-sensitive system: Discrepancy between DNA damage and dell death

2005 ◽  
Vol 39 (2) ◽  
pp. 213-220 ◽  
Author(s):  
Minyi Shi ◽  
Baohui Xu ◽  
Kazuko Azakami ◽  
Tomohiro Morikawa ◽  
Kunitomo Watanabe ◽  
...  
Keyword(s):  
Dna Damage ◽  
Vitamin C ◽  
Dual Role ◽  
Oxygen Sensitive
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