Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress, and induces caspase-dependent cell death in antiestrogen–sensitive and resistant ER+ breast cancer cells

Sudharsan Periyasamy-Thandavan; William H. Jackson; Julia S. Samaddar; Brian Erickson; John R. Barrett; Lauren Raney; Elangovan Gopal; Vadivel Ganapathy; William D. Hill; Kapil Bhalla; Patricia V. Schoenlein

doi:10.4161/auto.6.1.10323

Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress, and induces caspase-dependent cell death in antiestrogen–sensitive and resistant ER+ breast cancer cells

Autophagy ◽

10.4161/auto.6.1.10323 ◽

2010 ◽

Vol 6 (1) ◽

pp. 19-35 ◽

Cited By ~ 41

Author(s):

Sudharsan Periyasamy-Thandavan ◽

William H. Jackson ◽

Julia S. Samaddar ◽

Brian Erickson ◽

John R. Barrett ◽

...

Keyword(s):

Breast Cancer ◽

Endoplasmic Reticulum ◽

Cell Death ◽

Endoplasmic Reticulum Stress ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Dependent Cell ◽

Catabolic Process ◽

Dependent Mechanism

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Autophagy contributes to falcarindiol-induced cell death in breast cancer cells with enhanced endoplasmic reticulum stress

PLoS ONE ◽

10.1371/journal.pone.0176348 ◽

2017 ◽

Vol 12 (4) ◽

pp. e0176348 ◽

Cited By ~ 9

Author(s):

Tingting Lu ◽

Ming Gu ◽

Yan Zhao ◽

Xinyu Zheng ◽

Chengzhong Xing

Keyword(s):

Breast Cancer ◽

Endoplasmic Reticulum ◽

Cell Death ◽

Endoplasmic Reticulum Stress ◽

Cancer Cells ◽

Breast Cancer Cells

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Ribosomal protein L19 overexpression activates the unfolded protein response and sensitizes MCF7 breast cancer cells to endoplasmic reticulum stress-induced cell death

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2014.06.036 ◽

2014 ◽

Vol 450 (1) ◽

pp. 673-678 ◽

Cited By ~ 18

Author(s):

Mina Hong ◽

HyungRyong Kim ◽

Inki Kim

Keyword(s):

Breast Cancer ◽

Endoplasmic Reticulum ◽

Cell Death ◽

Endoplasmic Reticulum Stress ◽

Ribosomal Protein ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Unfolded Protein ◽

The Unfolded Protein Response ◽

Protein Response

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[Retracted] Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin‑1 in breast cancer cells

International Journal of Molecular Medicine ◽

10.3892/ijmm.2021.4997 ◽

2021 ◽

Vol 48 (2) ◽

Author(s):

Xiu Cheng ◽

Hao Liu ◽

Chen-Chen Jiang ◽

Lin Fang ◽

Chao Chen ◽

...

Keyword(s):

Breast Cancer ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Beclin 1

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CBIO-29. ACOT7 REGULATES COLONIZATION OF BREAST CANCER CELLS IN THE BRAIN BY REGULATING ENDOPLASMIC RETICULUM STRESS RESPONSE

Neuro-Oncology ◽

10.1093/neuonc/nox168.147 ◽

2017 ◽

Vol 19 (suppl_6) ◽

pp. vi38-vi38

Author(s):

Deepak Kanojia ◽

Wojciech K Panek ◽

Alex Cordero ◽

Annie Xiao ◽

Jason Miska ◽

...

Keyword(s):

Breast Cancer ◽

Endoplasmic Reticulum ◽

Stress Response ◽

Endoplasmic Reticulum Stress ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Endoplasmic Reticulum Stress Response ◽

The Brain

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RSK2 protects human breast cancer cells under endoplasmic reticulum stress through activating AMPKα2-mediated autophagy

Oncogene ◽

10.1038/s41388-020-01447-0 ◽

2020 ◽

Vol 39 (43) ◽

pp. 6704-6718

Author(s):

Lan-Ya Li ◽

Xi-Sha Chen ◽

Kuan-Song Wang ◽

Yi-Di Guan ◽

Xing-Cong Ren ◽

...

Keyword(s):

Breast Cancer ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast Cancer Cells ◽

Human Breast

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Ampelopsin Induces Cell Growth Inhibition and Apoptosis in Breast Cancer Cells through ROS Generation and Endoplasmic Reticulum Stress Pathway

PLoS ONE ◽

10.1371/journal.pone.0089021 ◽

2014 ◽

Vol 9 (2) ◽

pp. e89021 ◽

Cited By ~ 48

Author(s):

Yong Zhou ◽

Furong Shu ◽

Xinyu Liang ◽

Hui Chang ◽

Linying Shi ◽

...

Keyword(s):

Breast Cancer ◽

Endoplasmic Reticulum ◽

Cell Growth ◽

Endoplasmic Reticulum Stress ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Ros Generation ◽

Cell Growth Inhibition ◽

Endoplasmic Reticulum Stress Pathway ◽

Stress Pathway

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Modulation of nuclear factor-kappa B activation by the endoplasmic reticulum stress sensor PERK to mediate estrogen-induced apoptosis in breast cancer cells

Cell Death Discovery ◽

10.1038/s41420-017-0012-7 ◽

2018 ◽

Vol 4 (1) ◽

Cited By ~ 24

Author(s):

Ping Fan ◽

Amit K. Tyagi ◽

Fadeke A. Agboke ◽

Rohit Mathur ◽

Niranjana Pokharel ◽

...

Keyword(s):

Breast Cancer ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Nuclear Factor Kappa B ◽

Nuclear Factor ◽

Stress Sensor ◽

Nuclear Factor Kappa ◽

Induced Apoptosis

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Abstract 4442: Novel mechanism of gamma-tocotrienol-induced apoptosis in breast cancer cells: endoplasmic reticulum stress-dependent increase in death receptor signaling pathways

10.1158/1538-7445.am10-4442 ◽

2010 ◽

Author(s):

Sook-Kyung Park ◽

Bob G. Sanders ◽

Kimberly Kline

Keyword(s):

Breast Cancer ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Death Receptor ◽

Death Receptor Signaling ◽

Induced Apoptosis ◽

Stress Dependent ◽

Gamma Tocotrienol

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Abstract 2087: Estrogen receptor beta sensitizes breast cancer cells to endoplasmic reticulum stress-regulated apoptosis

10.1158/1538-7445.am2011-2087 ◽

2011 ◽

Author(s):

Gayani K. Rajapaksa ◽

Fotis Nikolos ◽

Christoforos G. Thomas ◽

Jan-Ake Gustafsson

Keyword(s):

Breast Cancer ◽

Endoplasmic Reticulum ◽

Estrogen Receptor ◽

Endoplasmic Reticulum Stress ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Estrogen Receptor Beta ◽

Receptor Beta

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Abstract 2332: Integral modulation of nuclear factor-kappa B activation by C/EBPβ and the endoplasmic reticulum stress sensor PERK to mediate estrogen-induced apoptosis in estrogen-deprived breast cancer cells

10.1158/1538-7445.am2017-2332 ◽

2017 ◽

Author(s):

Ping Fan ◽

Amit K. Tyagi ◽

Fadeke A. Agboke ◽

Niranjana Pokharel ◽

V. Craig Jordan

Keyword(s):

Breast Cancer ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Nuclear Factor Kappa B ◽

Nuclear Factor ◽

Stress Sensor ◽

Nuclear Factor Kappa ◽

Induced Apoptosis

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