scholarly journals Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illness

Autophagy ◽  
2008 ◽  
Vol 4 (1) ◽  
pp. 88-90 ◽  
Author(s):  
Robert S.B. Clark ◽  
Hülya Bayir ◽  
Charleen T. Chu ◽  
Sean M. Alber ◽  
Patrick M. Kochanek ◽  
...  
2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Sami Abu Hamdeh ◽  
Ganna Shevchenko ◽  
Jia Mi ◽  
Sravani Musunuri ◽  
Jonas Bergquist ◽  
...  

EBioMedicine ◽  
2019 ◽  
Vol 44 ◽  
pp. 607-617 ◽  
Author(s):  
Michael Eiden ◽  
Nicolas Christinat ◽  
Anirikh Chakrabarti ◽  
Sarah Sonnay ◽  
John-Paul Miroz ◽  
...  

Injury ◽  
2010 ◽  
Vol 41 ◽  
pp. S52-S53
Author(s):  
T. Frugier ◽  
D. O’Reilly ◽  
M.C. Morganti-Kossmann ◽  
C. McLean

1988 ◽  
Vol 254 (3) ◽  
pp. E287-E291 ◽  
Author(s):  
P. D. Woolf ◽  
R. W. Hamill ◽  
L. A. Lee ◽  
J. V. McDonald

The magnitude of circulating free and total (free plus conjugated) catecholamine responses to a strong and sustained stimulus was investigated in four groups of patients: traumatic brain injury (n = 24), vascular brain injury (n = 10), polysystem trauma (n = 7) and medical/surgical patients in an intensive care unit (n = 29). Despite significant three- to sevenfold elevations in both free and total norepinephrine (NE) and epinephrine (E), the ratio of free to total NE and E remained constant over a very broad range of values. The proportion of free E was twice normal (30.1-33.5 vs. 16.2%) in all but patients with polytrauma, whereas the percentage of free NE was unchanged in all patients (43.0%). All dopamine (DA) parameters remained generally normal. In the patients with traumatic or vascular brain injury, significant inverse correlations were present between the degree of neurological dysfunction, as indicated by the concomitant Glasgow coma score, and free NE, E, and DA and total NE and DA levels. Thus, during conditions of intense and prolonged catecholamine release, the proportion of free catecholamine remains constant and the total as well as free catecholamine concentration is proportional to the Glasgow coma score.


2016 ◽  
Vol 44 (12) ◽  
pp. 454-454
Author(s):  
Laura Wilson ◽  
Jennifer Thompson ◽  
Madeline Morrell ◽  
Rameela Chandrasekhar ◽  
Joanna Stollings ◽  
...  

Neuroreport ◽  
2019 ◽  
Vol 30 (5) ◽  
pp. 344-349 ◽  
Author(s):  
Yuxin He ◽  
Huiying Yan ◽  
Hongbin Ni ◽  
Weibang Liang ◽  
Wei Jin

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