scholarly journals Small Molecule Enhancers of Rapamycin-Induced TOR Inhibition Promote Autophagy, Reduce Toxicity in Huntington’s Disease Models and Enhance Killing of Mycobacteria by Macrophages

Autophagy ◽  
2007 ◽  
Vol 3 (6) ◽  
pp. 620-622 ◽  
Author(s):  
R. Andres Floto ◽  
Sovan Sarkar ◽  
Ethan O. Perlstein ◽  
Beate Kampmann ◽  
Stuart L. Schreiber ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Small Molecule ◽  
Disease Models ◽  
Small Molecule Enhancers

scholarly journals Identification and Evaluation of Small Molecule Pan-Caspase Inhibitors in Huntington’s Disease Models

2013 ◽  
Vol 20 (5) ◽  
pp. 742
Author(s):  
Melissa J. Leyva ◽  
Francesco DeGiacomo ◽  
Linda S. Kaltenbach ◽  
Jennifer Holcomb ◽  
Ningzhe Zhang ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Small Molecule ◽  
Disease Models ◽  
Caspase Inhibitors

scholarly journals Identification and Evaluation of Small Molecule Pan-Caspase Inhibitors in Huntington's Disease Models

2010 ◽  
Vol 17 (11) ◽  
pp. 1189-1200 ◽  
Author(s):  
Melissa J. Leyva ◽  
Francesco DeGiacomo ◽  
Linda S. Kaltenbach ◽  
Jennifer Holcomb ◽  
Ningzhe Zhang ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Small Molecule ◽  
Disease Models ◽  
Caspase Inhibitors

scholarly journals ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington’s disease models

2016 ◽  
Vol 11 (1) ◽  
Author(s):  
Mitchell S. Wold ◽  
Junghyun Lim ◽  
Véronik Lachance ◽  
Zhiqiang Deng ◽  
Zhenyu Yue
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Disease Models

scholarly journals A small molecule p75NTRligand normalizes signalling and reduces Huntington’s disease phenotypes in R6/2 and BACHD mice

2016 ◽  
pp. ddw316 ◽  
Author(s):  
Danielle A. Simmons ◽  
Nadia P. Belichenko ◽  
Ellen C. Ford ◽  
Sarah Semaan ◽  
Marie Monbureau ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Small Molecule ◽  
Disease Phenotypes
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