scholarly journals Reversible Heart Failure as a Result of Newly Diagnosed Primary Adrenal Insufficiency

2016 ◽  
Vol 2 (4) ◽  
pp. e321-e324 ◽  
Author(s):  
Kristen A. Hyland ◽  
Daniel S. Altman ◽  
Jennifer M. Perkins
Keyword(s):  
Heart Failure ◽  
Adrenal Insufficiency ◽  
Newly Diagnosed ◽  
Primary Adrenal Insufficiency

scholarly journals Adrenal failure and antiphospholipid syndrome

2020 ◽  
Vol 48 (7) ◽  
pp. 030006052090365
Author(s):  
Katarina Mlekuš Kozamernik ◽  
Mojca Jensterle ◽  
Aleš Ambrožič ◽  
Marija Pfeifer
Keyword(s):  
Adrenal Insufficiency ◽  
Antiphospholipid Syndrome ◽  
Signs And Symptoms ◽  
Stressful Situation ◽  
Adrenal Failure ◽  
Newly Diagnosed ◽  
Primary Adrenal Insufficiency ◽  
Severe Inflammation ◽  
Symptoms And Signs

We herein report two cases of primary adrenal insufficiency (AI) associated with antiphospholipid syndrome (APS). In both patients, the main finding that led to the diagnosis was hyponatraemia. The major difference between the two cases was the time at which AI evolved during the course of APS. In the first patient, AI developed acutely along with other presenting features of APS. In the second patient, the AI was unmasked during a stressful situation induced by severe inflammation that occurred 7 years after the first APS manifestation and had probably evolved slowly during the previous few years. These cases emphasise the importance of considering AI in patients with either suspected or newly diagnosed APS as well as in patients who have long been known to have APS. The symptoms and signs alerting the clinician to possible AI are general abdominal complaints, fever, hypotension, and hyponatraemia. Conversely, patients with primary AI should be questioned about the signs and symptoms of APS.

scholarly journals Primary adrenal insufficiency replacement therapy

2000 ◽  
Vol 46 (3) ◽  
pp. 31-45
Author(s):  
V. V. Fadeev ◽  
G. A. Melnichenko
Keyword(s):  
Heart Failure ◽  
Adrenal Insufficiency ◽  
Replacement Therapy ◽  
Adrenal Cortex ◽  
Adrenal Glands ◽  
Pathological Process ◽  
Clinical Syndrome ◽  
Primary Adrenal Insufficiency ◽  
Adrenal System ◽  
System 2

Adrenal insufficiency is a clinical syndrome caused by insufficient secretion of hormones by the adrenal cortex, which is the result of a malfunction of one or more parts of the hypothalamic-pituitary-adrenal system [2]. Primary chronic adrenal insufficiency (1-CNI) develops as a result of the destruction of more than 90% of the cortex of both adrenal glands by a pathological process. The main causes of 1-CNN are currently autoimmune (80–85%) and tuberculosis (5–10%) destruction of the adrenal cortex [2, 3]. 1-CNN of the indicated etiology is better known as "Addison's disease." 1-CNN is a relatively rare disease (40-110 new cases per 1 million people per year) [2, 3], but it is of considerable importance in the practice of endocrinology. Without exception, all patients with a diagnosis of 1-chronic heart failure need lifelong replacement therapy with corticosteroids (CS), which will be discussed in this work.

scholarly journals Reversible Biventricular Heart Failure Due to Primary Adrenal Insufficiency

2020 ◽  
Vol 2 (3) ◽  
pp. 411-413
Author(s):  
Ankita Devareddy ◽  
Konrad Teodor Sawicki ◽  
Lubna Choudhury ◽  
Jane E. Wilcox
Keyword(s):  
Heart Failure ◽  
Adrenal Insufficiency ◽  
Primary Adrenal Insufficiency

scholarly journals Prevalence of adrenal insufficiency among patients with euvolemic hyponatremia

2021 ◽  
Author(s):  
Amit Kumar ◽  
Maria Ghosh ◽  
Jubbin Jagan Jacob
Keyword(s):  
Adrenal Insufficiency ◽  
Stimulation Test ◽  
Newly Diagnosed ◽  
Acth Stimulation Test ◽  
Single Centre ◽  
Acth Stimulation ◽  
Primary Adrenal Insufficiency ◽  
General Medical Ward ◽  
Inhaled Steroids ◽  
Medical Inpatients

Background: The diagnosis of SIAD requires the exclusion of secondary adrenal insufficiency (AI) among patients with euvolemic hyponatremia (EuVHNa). Studies have suggested about 2.7% to 3.8% of unselected patients presenting to the emergency room with EuVHNa have undiagnosed AI and it is as high as 15% among patients admitted to specialized units for evaluation of hyponatremia. Objective: To study the prevalence of AI among inpatients with EuVHNa in a general medical ward setting Methods: This was a prospective, single centre observational study conducted among general medical inpatients with EuVHNa, defined as patients with a serum Na <135 mmol/L, clinical euvolemia and urine spot sodium >30mmol/L. Additionally patients with recent vomiting, current renal failure, diuretic use and those with uncontrolled hyperglycemia were excluded. Adrenal functions were assessed by a modified ACTH stimulation test called Acton Prolongatum™ stimulation test (APST). A cut off cortisol value of <18mg/dl after 60 minutes of ACTH injection was used to diagnose AI. Results: One hundred and forty-one (141) patients were included and underwent an APST. APST suggested 20/141 (14.2%) had undiagnosed AI. The most common cause of AI (9/20) was secondary AI because of the use of steroids including inhaled steroids and indigenous medicines contaminated with steroids. In 5 (3.5%) patients hypopituitarism was newly diagnosed. Despite primary adrenal insufficiency not commonly presenting as EuVHNa, 2/20 patients had primary adrenal insufficiency. Conclusions: AI is much commoner in our country among inpatients with EuVHNa primarily driven by exogenous steroid use and undiagnosed hypopituitarism.

Abstract #140: A Case of Primary Adrenal Insufficiency from Tuberculous Adrenalitis

2017 ◽  
Vol 23 ◽  
pp. 23-24
Author(s):  
Moses Ko ◽  
Timothy Quek ◽  
Yin Kon ◽  
Daniel Ek Kwang Chew
Keyword(s):  
Adrenal Insufficiency ◽  
Primary Adrenal Insufficiency
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