Postmortem Diagnosis of Diabetic Ketoacidosis Presenting as the "Dead-in-Bed Syndrome"

2014 ◽  
Vol 20 (7) ◽  
pp. e123-e125 ◽  
Author(s):  
Jennie Luna ◽  
M Gilliland ◽  
Karlene Hewan-Lowe ◽  
Robert Tanenberg
Keyword(s):  
Diabetic Ketoacidosis ◽  
Postmortem Diagnosis ◽  
Dead In Bed Syndrome ◽  
The Dead

scholarly journals Postmortem Diagnosis of Diabetic Ketoacidosis: An Autopsy Case

2016 ◽  
Vol 40 (1) ◽  
pp. 19 ◽  
Author(s):  
Jong-Pil Park ◽  
Hyun-Moo Kang ◽  
Yu Jin Won ◽  
Ik Jo Chung ◽  
Bong-Woo Lee
Keyword(s):  
Diabetic Ketoacidosis ◽  
Autopsy Case ◽  
Postmortem Diagnosis

The dead in bed syndrome revisited: a review of the evidence

2012 ◽  
Vol 2 (3) ◽  
pp. 233-241 ◽  
Author(s):  
Philip J Weston
Keyword(s):  
Dead In Bed Syndrome ◽  
The Dead

The ‘dead in bed syndrome’ – a cause of sudden death in Type 1 diabetes mellitus

2007 ◽  
Vol 51 (6) ◽  
pp. 843-845 ◽  
Author(s):  
R D Start ◽  
C Barber ◽  
R O C Kaschula ◽  
R T C E Robinson
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Sudden Death ◽  
Type 1 Diabetes Mellitus ◽  
Dead In Bed Syndrome ◽  
The Dead

Sudden death in type 1 diabetes: The mystery of the ‘dead in bed’ syndrome

2010 ◽  
Vol 138 (1) ◽  
pp. 91-93 ◽  
Author(s):  
Emily Tu ◽  
Stephen M. Twigg ◽  
Christopher Semsarian
Keyword(s):  
Type 1 Diabetes ◽  
Sudden Death ◽  
Dead In Bed Syndrome ◽  
The Dead

scholarly journals The Vital Role of Thanatochemistry in the Postmortem Diagnostic of Diabetic Ketoacidosis—Case Report

Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 988
Author(s):  
Nona Girlescu ◽  
Bogdan Stoica ◽  
Iuliana Hunea ◽  
Madalina Diac ◽  
Simona Irina Damian ◽  
...  
Keyword(s):  
Diabetic Ketoacidosis ◽  
Glycated Hemoglobin ◽  
Ketone Bodies ◽  
Vital Role ◽  
Postmortem Diagnosis ◽  
Initial Manifestation ◽  
Beta Hydroxybutyrate ◽  
Postmortem Examinations

Diabetic ketoacidosis (DKA) is a lethal acute hyperglycemic complication of diabetes mellitus (DM) and it represents the initial manifestation of DM in about 15–20% of cases in adults and about 30–40% of cases in children. Postmortem diagnosis of DKA can only be made by applying thanatochemistry. Biochemistry applied postmortem is viewed with skepticism by many practitioners in the forensic field, completely lacking in many forensic services around the world, and especially in the national ones. This article aims to underline the importance of the postmortem application of biochemistry by reviewing the case of a person in the third decade of life who died suddenly at home due to diabetic ketoacidosis (DKA), whose autopsy was performed at an early PMI of approximately 24 h. Routine postmortem examinations (macroscopic, anatomopathological, and toxicological) could not establish a clear cause of death. When attention was turned to biochemical determinations (i.e., determination of glycated hemoglobin, glucose and ketone bodies (acetone, beta-hydroxybutyrate) in the blood, vitreous humor, and cerebrospinal fluid), the identified values clarified the thanatogenic mechanisms by establishing the diagnosis of DKA.

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