Thyroid-Related Factors that Influence Preoperative Localization of Parathyroid Adenomas

2012 ◽  
Vol 18 (1) ◽  
pp. 26-33 ◽  
Author(s):  
Serhat Isik ◽  
Gulhan Akbaba ◽  
Dilek Berker ◽  
Yasemin Tutuncu ◽  
Ufuk Ozuguz ◽  
...  
Keyword(s):  
Preoperative Localization ◽  
Related Factors ◽  
Parathyroid Adenomas

Accurate Preoperative Localization of Parathyroid Adenomas With C-11 Methionine PET/CT

2013 ◽  
Vol 257 (6) ◽  
pp. 1124-1128 ◽  
Author(s):  
Theresia Weber ◽  
Clemens Maier-Funk ◽  
Dagmar Ohlhauser ◽  
Andreas Hillenbrand ◽  
Gregor Cammerer ◽  
...  
Keyword(s):  
Preoperative Localization ◽  
Pet Ct ◽  
Parathyroid Adenomas

Preoperative Localization of Parathyroid Adenomas Using99mTc-MIBI Scintigraphy in Patients with Hyperparathyroidism

1997 ◽  
Vol 4 (2) ◽  
pp. 126-129 ◽  
Author(s):  
Shoichi Ebisuno ◽  
Takeshi Inagaki ◽  
Toshihiko Yoshida ◽  
Motoki Yamamoto ◽  
Yoji Tabuse ◽  
...  
Keyword(s):  
Preoperative Localization ◽  
Parathyroid Adenomas ◽  
Mibi Scintigraphy

SPECT/CT’s Advantage for Preoperative Localization of Small Parathyroid Adenomas in Primary Hyperparathyroidism

2017 ◽  
Vol 42 (2) ◽  
pp. e109-e114 ◽  
Author(s):  
Patricia Sandqvist ◽  
Inga-Lena Nilsson ◽  
Per Grybäck ◽  
Alejandro Sanchez-Crespo ◽  
Anders Sundin
Keyword(s):  
Primary Hyperparathyroidism ◽  
Preoperative Localization ◽  
Parathyroid Adenomas

Value of Ultrasonography, CT and MR Imaging in the Diagnosis of Primary Hyperparathyroidism

1996 ◽  
Vol 37 (3P2) ◽  
pp. 720-726 ◽  
Author(s):  
C. Tziakouri ◽  
E. Eracleous ◽  
S. Skannavis ◽  
A. Pierides ◽  
P. Symeonides ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Primary Hyperparathyroidism ◽  
Detection Rate ◽  
Cost Effective ◽  
Clinical Results ◽  
Parathyroid Glands ◽  
Preoperative Localization ◽  
Confirmatory Test ◽  
Parathyroid Adenomas ◽  
Ectopic Parathyroid

Purpose: To evaluate the significance of preoperative localization of abnormal parathyroid glands to the surgical outcome in patients with primary hyperparathyroidism. Material and Methods: Thirty-nine patients with primary hyperparathyroidism were studied preoperatively with US (39 patients), CT (30 patients) and MR imaging (18 patients). The overall diagnostic accuracy for US was 87%, CT 66% and MR 94%. In patients with a single parathyroid adenoma US was the most cost-effective localization technique with a detection rate of 96%. CT had a lower detection rate (78%) but was of particular value for fairly large ectopic adenomas in the root of the neck. MR imaging was a good confirmatory test (93%). In patients with multiple gland disease (primary hyperplasia and multiple adenomas), no single localization study alone was sufficient. Combination of all 3 studies, however, alerted the physician to the presence of disease in more than one gland in 87% of these patients. Conclusion: US, CT and MR imaging followed by surgery performed by an experienced surgeon provided good clinical results in 39 patients with primary hyperparathyroidism. Preoperative localization was especially useful in patients with primary parathyroid hyperplasia or multiple adenomas and in patients with ectopic parathyroid adenomas in the root of the neck. We recommend identification of all abnormal parathyroid glands prior to surgery.

scholarly journals Can Met-PET/CT Predict Sporadic Multiglandular Hyperparathyroidism? Report of a Case and Review of the Literature

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Andreas Hillenbrand ◽  
Johannes Lemke ◽  
Doris Henne-Bruns ◽  
Ambros J. Beer ◽  
Vikas Prasad
Keyword(s):  
Posterior Mediastinum ◽  
Parathyroid Glands ◽  
Preoperative Localization ◽  
Surgical Removal ◽  
Increased Risk ◽  
Pet Ct ◽  
Parathyroid Adenomas ◽  
Patients At Risk ◽  
Ectopic Parathyroid ◽  
Met Pet

Background. Primary hyperparathyroidism (pHPT) is a common endocrine disorder of the parathyroid glands. In most cases pHPT is caused by single gland disease, but about 10% of patients suffer from sporadic multiglandular disease (MGD). Patients with MGD, especially with ectopic parathyroid adenomas, have an increased risk for persistence/recurrence after surgery. Normally, sporadic MGD cannot be diagnosed preoperatively by parathyroid scintigraphy. We analyzed the potential of positron emission tomography/computed tomography (Met-PET/CT) to predict MGD. Methods and Case Presentation. We reviewed the literature, if preoperative Met-PET/CT could predict MGD in patients with pHPT. Further, we present a 71-year-old female with ectopic MGD. Preoperative localization via Met-PET/CT showed MGD with two areas suspected to be enlarged parathyroid glands (left lateral to the thyroid lobe and posterior mediastinum). Both diagnostic findings were extirpated and parathormone dropped into normal levels. Results. We identified four additional manuscripts, referring to MGD and Met-PET/CT with divergent results. Preoperative localization diagnostics using Met-PET/CT may not necessarily identify MGD. In most cases, Met-PET/CT localized only one adenoma and localizes larger adenomas more reliably than smaller adenomas. Conclusion. Identifying patients at risk of MGD preoperatively remains challenging. We found MET-PET/CT seems to predict MGD in patients with large size and high weight PTH adenomas. For ectopic parathyroid adenomas, accurate preoperative localization is the key to successful surgical removal. Met-PET/CT appears to have great potential in soft-tissue analysis of complex anatomical regions and can predict ectopic parathyroid adenomas.

scholarly journals The Clinical Features of Cystic Parathyroid Adenoma in Chinese Population: A Single-Center Experience

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Ya Hu ◽  
Ming Cui ◽  
Yu Xia ◽  
Zhe Su ◽  
Xiang Zhang ◽  
...  
Keyword(s):  
Parathyroid Adenoma ◽  
Needle Aspiration ◽  
Inorganic Phosphorus ◽  
Preoperative Localization ◽  
Tumor Diameter ◽  
Ipth Level ◽  
College Hospital ◽  
Cystic Fluid ◽  
Parathyroid Adenomas

Objective. Cystic parathyroid adenoma is a rare cause of primary hyperparathyroidism, but its preoperative diagnosis and management remain inconclusive. Method. We retrospectively identified patients with cystic parathyroid adenomas who underwent surgery at Peking Union Medical College Hospital. Results. Patients with cystic parathyroid adenomas had higher serum intact parathyroid hormone and calcium levels, larger maximum tumor diameter, and lower serum inorganic phosphorus level than did those with solid adenomas. Patients with cystic adenomas were predominantly male, and hypercalcemic crisis and atypical adenomas were common. The accuracy of preoperative localization methodologies was lower in patients with cystic adenomas than in patients with solid adenomas. US-guided fine-needle aspiration was performed in 11 patients. In all patients, the iPTH level in cystic fluid was much higher than that in serum. No sign of recurrence was observed after a median follow-up of 39 months. Conclusions. Cystic parathyroid adenomas may not be as rare as previously reported. FNA may be a safe and feasible localization methodology for patients with inconclusive preoperative localization methodologies. Close follow-up is necessary for patients with cystic parathyroid adenomas, which account for a substantial proportion of atypical adenoma cases.

Sign in / Sign up

Export Citation Format

Share Document