USE OF IODINE-123 AS A DIAGNOSTIC TRACER FOR NECK AND WHOLE-BODY SCANNING IN PATIENTS WITH WELL-DIFFERENTIATED THYROID CANCER

1998 ◽  
Vol 4 (1) ◽  
pp. 11-16 ◽  
Author(s):  
Recaredo Berbano, MD ◽  
Sleiman Naddaf, MD ◽  
Elsa Echemendia, MD, FACE ◽  
Jean Barsa, MD ◽  
Halil Turoglu, MD ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Whole Body ◽  
Body Scanning ◽  
Iodine 123 ◽  
Well Differentiated

Value of Diagnostic Radioiodine Whole-body Scanning after Initial Therapy in Patients with Differentiated Thyroid Cancer at Intermediate and High Risk for Recurrence

Thyroid ◽  
2012 ◽  
pp. 120724120054001
Author(s):  
Pedro Weslley Rosario ◽  
Mariana de Souza Furtado ◽  
Augusto Flavio Campos Mineiro Filho ◽  
Rafaela Xavier Lacerda ◽  
Maria Regina Calsolari
Keyword(s):  
Thyroid Cancer ◽  
High Risk ◽  
Differentiated Thyroid Cancer ◽  
Initial Therapy ◽  
Whole Body ◽  
Body Scanning

scholarly journals Pre-ablative Diagnostic Whole-body Scan Following Total Thyroidectomy for Well-differentiated Thyroid Cancer: Is It Necessary?

2005 ◽  
Vol 28 (2) ◽  
pp. 90-96 ◽  
Author(s):  
Choon Meng Teoh ◽  
Muhammad Rohaizak ◽  
Kin Yoong Chan ◽  
Ali Yaakub Jasmi ◽  
Ismail Fuad
Keyword(s):  
Thyroid Cancer ◽  
Total Thyroidectomy ◽  
Differentiated Thyroid Cancer ◽  
Whole Body ◽  
Whole Body Scan ◽  
Body Scan ◽  
Well Differentiated

scholarly journals 123I Isotope as a Diagnostic Agent in the Follow-Up of Patients with Differentiated Thyroid Cancer: Comparison with Post131I Therapy Whole Body Scanning

2001 ◽  
Vol 86 (11) ◽  
pp. 5294-5300 ◽  
Author(s):  
Ali S. Alzahrani ◽  
Siema Bakheet ◽  
Majid Al Mandil ◽  
Alya Al-Hajjaj ◽  
Abdulraouf Almahfouz ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Whole Body ◽  
Body Scanning ◽  
Diagnostic Agent

scholarly journals Radioiodine treatment of metastatic differentiated thyroid cancer in patients on L-thyroxine, using recombinant human TSH

2001 ◽  
pp. 5-11 ◽  
Author(s):  
F Lippi ◽  
M Capezzone ◽  
F Angelini ◽  
D Taddei ◽  
E Molinaro ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Advanced Disease ◽  
Thyroid Stimulating Hormone ◽  
Whole Body ◽  
Suppressive Therapy ◽  
Serum Thyroglobulin ◽  
Body Scanning ◽  
Iodine 131 ◽  
Post Therapy

OBJECTIVE: This study tested the hypothesis that administration of human recombinant thyroid-stimulating hormone (rhTSH: Thyrogen, thyrotropin alpha) could promote iodine-131 ((131)I) uptake in the therapy for metastatic or locally invasive differentiated thyroid cancer (DTC), obviating L-thyroxine suppressive therapy (L-T4) withdrawal and hypothyroidism in patients with advanced disease. METHODS: Twelve totally (or almost completely) thyroidectomized adults, nine of whom had received earlier therapy after L-T4 withdrawal, underwent (131)I treatment while euthyroid on L-T4, after rhTSH administration. Nine underwent diagnostic whole-body scanning (WBS) after two consecutive daily i.m. injections (0.9 mg) of rhTSH. They then received an identical second course of rhTSH to promote therapeutic (131)I uptake. Post-therapy WBS was performed one week later. Three patients received only rhTSH (131)I therapy. RESULTS: Administration of rhTSH promoted (131)I uptake in all patients, as demonstrated by post-therapy WBS. Administration of rhTSH also promoted a significant increase in serum thyroglobulin (Tg) concentrations. According to the most recent measurements, 3-12 months after therapy, serum Tg levels fell in four, and stabilized in two out of eleven patients. Upon additional rhTSH-WBS 8 months post-study, a reduction in one metastatic site was noted in one patient. The rhTSH was well tolerated, with mild, transient fever and/or nausea occurring in only a minority of patients. Individuals with bone metastases experienced degrees of peritumoral pain and swelling that were similar (though more short-lived) to those seen in the same or other patients after L-T4 withdrawal. CONCLUSIONS: Administration of rhTSH is a safe, successful tool for inducing (131)I uptake in local and metastatic DTC lesions, and avoids L-T4 withdrawal, preserving metabolic homeostasis and preventing the debilitating effects of hypothyroidism.

Diagnostic Whole-Body Scanning Before Radioiodine Therapy for Pulmonary Metastases of Differentiated Thyroid Cancer

2008 ◽  
Vol 33 (12) ◽  
pp. 845-851 ◽  
Author(s):  
Yasushi Tachi ◽  
Shingo Iwano ◽  
Katsuhiko Kato ◽  
Masanori Tadokoro ◽  
Shinji Naganawa
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Radioiodine Therapy ◽  
Pulmonary Metastases ◽  
Whole Body ◽  
Body Scanning
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