TWICE-RECURRENT PRIMARY HYPERPARATHYROIDISM DUE TO PARATHYROID HYPERPLASIA IN AN ECTOPIC SUPERNUMERARY GLAND

2006 ◽  
Vol 12 (2) ◽  
pp. 165-169 ◽  
Author(s):  
Thomas H. Alexander ◽  
Andrew D. Beros ◽  
Lisa A. Orloff
Keyword(s):  
Primary Hyperparathyroidism ◽  
Parathyroid Hyperplasia ◽  
Supernumerary Gland

scholarly journals Primary Hyperparathyroidism due to Parathyroid Adenoma Originated from Supernumerary Gland

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Fernando Mendoza-Moreno ◽  
Ángel Rodriguez-Pascual ◽  
María Rocío Díez-Gago ◽  
Marina Pérez-González ◽  
Laura Jiménez‐Alvárez ◽  
...  
Keyword(s):  
Primary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Parathyroid Gland ◽  
Imaging Techniques ◽  
High Sensitivity ◽  
Parathyroid Glands ◽  
Parathyroid Surgery ◽  
Thyroid Lobe ◽  
The Impact ◽  
Supernumerary Gland

Introduction. The variability of the location of the parathyroid glands is directly related to the events that occur during embryonic development. The impact that an individual submits more than four parathyroid glands is close to 13%. However the presentation of a parathyroid adenoma in a supernumerary gland is an uncommon event. Case report. A 30-year-old man diagnosed with primary hyperparathyroidism with matching findings on ultrasonography and scintigraphy for parathyroid adenoma localization lower left regarding the thyroid gland. A cervicotomy explorer showed four orthotopic parathyroid glands. The biopsy of the inferior left gland was normal. No signs of adenoma were seen in the biopsy. Following mobilization of the ipsilateral thyroid lobe, fifth parathyroid gland was found increased significantly in size than proceeded to remove, confirming the diagnosis of adenoma. After the excision, the levels of serum calcium and parathyroid hormone were normalized. Conclusions. The presentation of a parathyroid adenoma in a supernumerary gland is a challenge for the surgeon. The high sensitivity having different imaging techniques has been a key to locate preoperatively the pathological parathyroid gland. Analytical or clinical persistence of primary hyperparathyroidism after parathyroid surgery can occur if the location of the adenoma is a supernumerary or ectopic gland location.

Primary Hyperparathyroidism in an Infant with Three Parathyroid Glands and Pulmonary Calcinosis

2001 ◽  
Vol 14 (8) ◽  
Author(s):  
A. Kemal Topaloglu ◽  
Bilgin Yuksel ◽  
Recep Tuncer ◽  
Neslihan O. Mungan ◽  
Guler Ozer
Keyword(s):  
Primary Hyperparathyroidism ◽  
Male Infant ◽  
Parathyroid Glands ◽  
Parathyroid Hyperplasia ◽  
Total Parathyroidectomy ◽  
Imaging Studies ◽  
Severe Hypercalcemia ◽  
Pulmonary Calcinosis

AbstractA 2 month-old male infant presented with severe hypercalcemia due to parathyroid hyperplasia. A total parathyroidectomy and partial heterotopic autotransplantation were carried out. Hypercalcemia recurred two months later. Normocalcemia was re-established after removing one half of the implanted tissue. Despite two separate surgical explorations and several imaging studies, including

Recurrent Acute Pancreatitis in Pregnancy Caused by Parathyroid Hyperplasia: A Case Report and Literature Review

2020 ◽  
Vol 103 (9) ◽  
pp. 952-959
Keyword(s):  
Acute Pancreatitis ◽  
Case Report ◽  
Primary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Epigastric Pain ◽  
Present Report ◽  
Parathyroid Hyperplasia ◽  
Pathological Examination ◽  
Recurrent Acute Pancreatitis ◽  
First Case

Background: Hypercalcemia during pregnancy leads to multiple maternal and fetal complications. To date, fewer than 30 cases of primary hyperparathyroidism (PHPT)-induced pancreatitis have been diagnosed during pregnancy. Most cases have been caused by a parathyroid adenoma. In the present report, the author described the first case of PHPT due to parathyroid hyperplasia presented with recurrent, acute pancreatitis during pregnancy. Case Report: A 38-year-old female, with a history of acute pancreatitis during her first pregnancy, presented with severe epigastric pain, nausea, and vomiting for three days at 24 weeks of gestation. Parathyroid-dependent, hypercalcemia-induced recurrence of pancreatitis was diagnosed based on the clinical presentation and laboratory investigations. An ultrasound on her neck revealed a possible parathyroid adenoma located on the inferior pole of the left thyroid gland. She underwent an uneventful left-lower parathyroidectomy. The pathological examination revealed parathyroid hyperplasia. Her serum calcium and parathyroid hormone levels returned to normal after surgery. She delivered a healthy male newborn at gestational age 38 weeks without any complications. Conclusion: PHPT-induced acute pancreatitis during pregnancy is rare. Hypercalcemia, involving both total and ionized calcium, should be investigated in pregnant women who present with acute pancreatitis. Early diagnosis and appropriate management can significantly improve the maternal, fetal, and pregnancy outcomes. Keywords: Hypercalcemia, Recurrent pancreatitis, Pregnancy, Primary hyperparathyroidism, Parathyroid hyperplasia

Verified data on parathyroid hyperplasia incidence not related to primary hyperparathyroidism in persons exposed to ionizing radiation

2019 ◽  
Author(s):  
Oleksii Kaminskyi ◽  
Olga Kopilova ◽  
Dmitrii Afanasyev ◽  
Konstantin Loganovskyi ◽  
Viktoria Talko ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Primary Hyperparathyroidism ◽  
Parathyroid Hyperplasia

scholarly journals Primary hyperparathyroidism caused by enormous unilateral water-clear cell parathyroid hyperplasia

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Georgios Boutzios ◽  
Helen Sarlanis ◽  
Anna Kolindou ◽  
Antigoni Velidaki ◽  
Theodore Karatzas
Keyword(s):  
Primary Hyperparathyroidism ◽  
Clear Cell ◽  
Parathyroid Hyperplasia

scholarly journals Multiple Endocrine Neoplasia or Accidental Association?

2020 ◽  
Author(s):  
Georgiana Cristina Taujan ◽  
Felicia Baleanu ◽  
Linda Spinato ◽  
Ruth Duttmann ◽  
Rafik Karmali ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Primary Hyperparathyroidism ◽  
Thyroid Carcinoma ◽  
Genetic Predisposition ◽  
Multiple Endocrine Neoplasia ◽  
Genetic Mutation ◽  
Parathyroid Hyperplasia ◽  
Papillary Thyroid ◽  
Endocrine Neoplasia

Pheochromocytoma, papillary thyroid carcinoma and hyperparathyroidism have rarely been reported together. Whether this association is coincidental or results from an unknown genetic predisposition is difficult to ascertain. We present the case of a patient who was diagnosed with pheochromocytoma, bilateral papillary thyroid carcinoma and parathyroid hyperplasia with primary hyperparathyroidism. A genetic mutation was hypothesized as the connection between these lesions. Previously described mutations were explored.

scholarly journals Atypical parathyroid adenomas as a rare cause of primary hyperparathyroidism - in an academic institution experience

2021 ◽  
Author(s):  
Grzegorz Kowalski ◽  
Grzegorz Buła ◽  
Adam Bednarczyk ◽  
Agata Gawrychowska ◽  
Jacek Gawrychowski
Keyword(s):  
Retrospective Study ◽  
Primary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Parathyroid Carcinoma ◽  
Clinical Presentation ◽  
Parathyroid Hyperplasia ◽  
Endocrine Surgery ◽  
Parathyroid Adenomas ◽  
Multiple Gland Disease ◽  
Atypical Parathyroid Adenoma

Abstract BACKGROUND Primary hyperparathyroidism (PHPT) is caused by benign and malignant conditions. Most commonly by typical adenoma/single gland disease (PA) - this is 80-85% cases of PHPT. Parathyroid hyperplasia or multiple gland disease accounts for 10-15% of cases of PHPT. Atypical parathyroid adenoma (APA) and carcinoma (PC) - very rare conditions - are both responsible for PHPT in approximately 0,5 - 1,5% of cases. OBJECTIVES To estimate occurrence of atypical parathyroid adenoma, parathyroid carcinoma and parathyroid hyperplasia along with characterize them based on their etiology, clinical presentation, diagnosis and treatment METHODS We performed a retrospective study and enrolled 1,019 patients with primary hyperparathyroidism undergoing parathyroidectomy at academic Department of General and Endocrine Surgery between 1983 and 2018. RESULTS Out of 1,019 cases of primary hyperparathyroidism, 850 (83.4%) cases were due to typical parathyroid adenoma (PA), 135 (13.2%) cases were due to parathyroid hyperplasia, 29 (2.8%) cases were due to parathyroid carcinoma (PC), and 5 (0.5%) cases were due to atypical parathyroid adenoma (APA).

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