LEVOTHYROXINE REPLACEMENT THERAPY IN PATIENTS WITH SUBCLINICAL HYPOTHYROIDISM AND CORONARY ARTERY DISEASE

2006 ◽  
Vol 12 (1) ◽  
pp. 5-17 ◽  
Author(s):  
Valentin V. Fadeyev ◽  
Julia Sytch ◽  
Viktor Kalashnikov ◽  
Alexander Rojtman ◽  
Abram Syrkin ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Replacement Therapy ◽  
Subclinical Hypothyroidism ◽  
Levothyroxine Replacement ◽  
Artery Disease

No effect of oral hormone replacement therapy on platelet function in postmenopausal women with coronary artery disease

2006 ◽  
Vol 96 (12) ◽  
pp. 862-863
Author(s):  
Nailin Li ◽  
Margita Eriksson-Berg ◽  
Britt-Marie Landgren ◽  
Karin Schenck-Gustafsson ◽  
Paul Hjemdahl ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Hormone Replacement Therapy ◽  
Coronary Artery ◽  
Replacement Therapy ◽  
Postmenopausal Women ◽  
Platelet Function ◽  
Hormone Replacement ◽  
Artery Disease

scholarly journals Prevalence and association of thyroid disorders with selected risk factors and severity of disease in patients confirmed of Coronary Artery Disease

2020 ◽  
Vol 19 (4) ◽  
pp. 678-684
Author(s):  
EM Samantha Bardara ◽  
Sagarika Ekanayake ◽  
Chandanie Wanigatunge ◽  
Aruna Kapuruge ◽  
GA Sarath Kumara
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Subclinical Hypothyroidism ◽  
Bypass Graft ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Gensini Score ◽  
Anthropometric Data ◽  
Artery Disease ◽  
Lipid Parameters

Objective: Subclinical hypothyroidism (SCH) has been identified as a risk for atherosclerosis and Coronary Artery Disease (CAD). The aim of this study was to determine the prevalence and association between hypothyroidism or subclinical hypothyroidism (SCH) and lipid parameters, anthropometric data and the severity of coronary artery disease (CAD) in patients awaiting Coronary Artery Bypass Graft Surgery (CABG) from a selected center. Method: A cross sectional analytical study was carried out amony patients awaiting CABG in a selected center. Thyroid profile (enzyme immunoassay method), lipoprotein (a) [Lp(a)], C- reactive protein (CRP) (immunoturbidimetric method) were determined and the Gensini score calculated. Lipid parameters and details of current medication were obtained from the medical records and anthropometric data were measured. Results: From a total of 102 patients 3% were on treatment for hypothyroidism and 15% had subclinical hypothyroidism. A significantly high (p= 0.04) percentage of SCH patients (75%) were dyslipidemic. There were no significant differences observed in lipid profiles and Lp(a) among SCH and euthyroid patients when the total sample or dyslipidemic sample was considered. However, a significantly high percentage (58%, p<0.05) of SCH patients on statins had a higher level of low density lipoprotein cholesterol (LDLc) compared to euthyroid dyslipidemic patients. A significant negative (p< 0.05) correlation was observed between thyroid stimulating hormone concentration and high density lipoprotein cholesterol (r= -0.67) in SCH group. No significant differences were observed in anthropometric data, CRP or Gensini score of SCH and euthyroid patients with CAD. Conclusion: The prevalence of dyslipidemia among SCH patients with CAD was significantly high. The patients suffering from SCH exhibited higher levels of LDLc compared to euthyroid patients from both the total and dyslipidemic groups. SCH patients under statin treatment displayed a higher LDLc suggesting a strong association between coronary artery disease and thyroid disease. Bangladesh Journal of Medical Science Vol.19(4) 2020 p.678-684

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