Prospective Study of Serum Androgen Levels Stratified by Increased or Normal Serum Follicle-Stimulating Hormone in Infertile Women with Regular Menses

1996 ◽  
Vol 2 (6) ◽  
pp. 375-378
Author(s):  
Jerome H. Check ◽  
Mark Peymer
Keyword(s):  
Prospective Study ◽  
Follicle Stimulating Hormone ◽  
Normal Serum ◽  
Infertile Women ◽  
Regular Menses ◽  
Androgen Levels ◽  
Stimulating Hormone

scholarly journals Pilot study of the optimal protocol of low dose step-up follicle stimulating hormone therapy for infertile women

2018 ◽  
Vol 17 (3) ◽  
pp. 315-324 ◽  
Author(s):  
Toshiya Matsuzaki ◽  
Takeshi Iwasa ◽  
Rie Yanagihara ◽  
Mizuki Komasaka ◽  
Kiyohito Yano ◽  
...  
Keyword(s):  
Pilot Study ◽  
Hormone Therapy ◽  
Low Dose ◽  
Follicle Stimulating Hormone ◽  
Infertile Women ◽  
Optimal Protocol ◽  
Dose Step ◽  
Stimulating Hormone

scholarly journals Ovarian Stimulation in Obese and Non-Obese Polycystic Ovary Syndrome Using a Low-Dose Step-Up Regimen with Two Different Starting Doses of Recombinant Follicle-Stimulating Hormone

2008 ◽  
Vol 36 (6) ◽  
pp. 1197-1204 ◽  
Author(s):  
R Yildizhan ◽  
E Adali ◽  
A Kolusari ◽  
M Kurdoglu ◽  
B Yildizhan ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Low Dose ◽  
Polycystic Ovary ◽  
Follicle Stimulating Hormone ◽  
Obese Group ◽  
Ovary Syndrome ◽  
Infertile Women ◽  
Starting Dose ◽  
Dose Step ◽  
Stimulating Hormone

Sixty-seven infertile women with polycystic ovary syndrome (PCOS) were divided into two groups, obese and non-obese, according to their body mass index. Waist-to-hip ratio, insulin resistance, total testosterone and dehydroepiandrosterone sulphate levels were significantly elevated in obese, compared with non-obese, patients. Both groups were treated with a low-dose step-up protocol of recombinant follicle-stimulating hormone (rFSH) with a starting dose of 50 IU/day and, every third day, a 25-IU increase in the dose until the appropriate dose was achieved for each individual, up to a maximum of 175 IU/day. In the obese group only, repeat therapy commenced in the second ovulatory cycle in women who had not become pregnant, however a starting dose of 75 IU/day was then used, with incremental and maximum dose as before. The results of the starting dose of 75 IU/day rFSH were compared with the results of a 50 IU/day rFSH starting dose in the obese group. A starting dose of 50 IU/day rFSH in a low-dose step-up regimen was found to be effective, safe and well-tolerated for inducing follicular development in non-obese infertile women with PCOS. However, for obese PCOS patients, a starting dose of 75 IU/day rFSH is recommended.

scholarly journals Interactions of Cortisol and Prolactin with Other Selected Menstrual Cycle Hormones Affecting the Chances of Conception in Infertile Women

2020 ◽  
Vol 17 (20) ◽  
pp. 7537
Author(s):  
Artur Wdowiak ◽  
Dorota Raczkiewicz ◽  
Paula Janczyk ◽  
Iwona Bojar ◽  
Marta Makara-Studzińska ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Follicle Stimulating Hormone ◽  
Thyroid Stimulating Hormone ◽  
Control Group ◽  
Infertile Women ◽  
The Third ◽  
Potential Factors ◽  
Infertile Group ◽  
Present Understanding ◽  
Stimulating Hormone

One of the major problems of success in infertility treatment could depend on the understanding how the potential factors may affect the conception. The aim of this study was to evaluate present understanding of such factors or hormonal causes that may induce infertility. We studied the interactions between the two menstrual cycle hormones i.e., cortisol (COR) and prolactin (PRL), along with the ultrasonographic ovulation parameters in a group of N = 205 women with diagnosed infertility. The control group consisted of N = 100 women with confirmed fertility. In both groups, follicle-stimulating hormone (FSH), luteinizing hormone (LH), anti-Müllerian hormone (AMH), thyroid stimulating hormone (TSH), PRL, COR were examined on the third day of the cycle, and estradiol (E2), progesterone (P), and COR were examined during ovulation and 7-days afterwards. In the infertile group, higher levels of PRL and COR were observed than that of in the control group. Cortisol levels at all phases of the menstrual cycle and PRL negatively correlated with E2 secretion during and after ovulation, thus contributed to the attenuation of the ovulatory LH surge. Infertile women who conceived presented with higher levels of E2 during and after ovulation, higher P after ovulation, and thicker endometrium than that of the women who failed to conceive. In conclusion, elevated secretion of COR and PRL in infertile women impairs the menstrual cycle by decreasing the pre-ovulatory LH peak and E2 and postovulatory E2 levels that affect the endometrial growth, and consequently reduce the chances to conceive.

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