Predicting feasibility and characterizing performance of extended-release formulations using physiologically based pharmacokinetic modeling

Jonathan Brown; John Crison; Peter Timmins

doi:10.4155/tde.12.81

Predicting feasibility and characterizing performance of extended-release formulations using physiologically based pharmacokinetic modeling

Therapeutic Delivery ◽

10.4155/tde.12.81 ◽

2012 ◽

Vol 3 (9) ◽

pp. 1047-1059 ◽

Cited By ~ 13

Author(s):

Jonathan Brown ◽

John Crison ◽

Peter Timmins

Keyword(s):

Extended Release ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Extended Release Formulations

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Physiologically Based Pharmacokinetic Modeling for Substitutability Analysis of Venlafaxine Hydrochloride Extended-Release Formulations Using Different Release Mechanisms: Osmotic Pump Versus Openable Matrix

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2016.06.015 ◽

2016 ◽

Vol 105 (10) ◽

pp. 3088-3096 ◽

Cited By ~ 2

Author(s):

Ho-Pi Lin ◽

Dajun Sun ◽

Xinyuan Zhang ◽

Hong Wen

Keyword(s):

Extended Release ◽

Pharmacokinetic Modeling ◽

Osmotic Pump ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Release Mechanisms ◽

Physiologically Based ◽

Venlafaxine Hydrochloride ◽

Extended Release Formulations

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Physiologically Based Pharmacokinetic Modeling to Evaluate Formulation Factors Influencing Bioequivalence of Metoprolol Extended‐Release Products

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1475 ◽

2019 ◽

Keyword(s):

Extended Release ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Factors Influencing ◽

Physiologically Based ◽

Formulation Factors

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Physiologically Based Pharmacokinetic Modeling to Evaluate Formulation Factors Influencing Bioequivalence of Metoprolol Extended‐Release Products

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1017 ◽

2019 ◽

Cited By ~ 1

Author(s):

Sumit Basu ◽

Haitao Yang ◽

Lanyan Fang ◽

Mario Gonzalez‐Sales ◽

Liang Zhao ◽

...

Keyword(s):

Extended Release ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Factors Influencing ◽

Physiologically Based ◽

Formulation Factors

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Physiologically-based pharmacokinetic modeling of different size polyethylene glycol-coated gold nanoparticles in mice

10.1615/ihtc16.nmt.023362 ◽

2018 ◽

Author(s):

Linjing Deng ◽

Jinping Zhao ◽

Yufeng Miao ◽

Xu Hu ◽

Qihong Deng

Keyword(s):

Gold Nanoparticles ◽

Polyethylene Glycol ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically-Based Pharmacokinetic Modeling to Predict Changes in Drug Exposure during Pregnancy Using the Simcyp Simulator

10.26226/morressier.57d6b2b7d462b8028d88e945 ◽

2016 ◽

Author(s):

Suvarchala Kiranmai Avvari

Keyword(s):

Drug Exposure ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Exposure During Pregnancy

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Physiologically‐Based Pharmacokinetic Modeling of Atorvastatin Incorporating Delayed Gastric Emptying and Acid‐to‐Lactone Conversion

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12447 ◽

2019 ◽

Vol 8 (9) ◽

pp. 664-675 ◽

Cited By ~ 5

Author(s):

Bridget L. Morse ◽

Jeffrey J. Alberts ◽

Maria M. Posada ◽

Jessica Rehmel ◽

Anil Kolur ◽

...

Keyword(s):

Gastric Emptying ◽

Delayed Gastric Emptying ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Preliminary physiologically based pharmacokinetic modeling of renally cleared drugs in Chinese pregnant women

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2243 ◽

2020 ◽

Vol 41 (6) ◽

pp. 248-267 ◽

Cited By ~ 1

Author(s):

Ling Song ◽

Zhiheng Yu ◽

Yifan Xu ◽

Xiaobei Li ◽

Xuanlin Liu ◽

...

Keyword(s):

Pregnant Women ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Prediction of fluoxetine and norfluoxetine pharmacokinetic profiles using physiologically based pharmacokinetic modeling

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1927 ◽

2021 ◽

Author(s):

Hyeon‐Cheol Jeong ◽

Yoon‐Jee Chae ◽

Sooyeun Lee ◽

Wonku Kang ◽

Hwi‐yeol Yun ◽

...

Keyword(s):

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Pharmacokinetic Profiles ◽

Physiologically Based

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Physiologically Based Pharmacokinetic Modeling Approach to Predict Drug‐Drug Interactions With Ethionamide Involving Impact of Genetic Polymorphism on FMO3

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1378 ◽

2019 ◽

Vol 59 (6) ◽

pp. 880-889 ◽

Cited By ~ 1

Author(s):

Phuong Thi Thu Nguyen ◽

Md Masud Parvez ◽

Min Jung Kim ◽

Sung Eun Yoo ◽

Sangzin Ahn ◽

...

Keyword(s):

Genetic Polymorphism ◽

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically Based Pharmacokinetic Modeling and Tissue Distribution Characteristics of SHetA2 in Tumor-Bearing Mice

The AAPS Journal ◽

10.1208/s12248-020-0421-z ◽

2020 ◽

Vol 22 (2) ◽

Author(s):

Ankur Sharma ◽

Mengjie Li ◽

Elangovan Thavathiru ◽

Mariam Ibrahim ◽

Lucila Garcia-Contreras ◽

...

Keyword(s):

Tissue Distribution ◽

Pharmacokinetic Modeling ◽

Distribution Characteristics ◽

Physiologically Based Pharmacokinetic Modeling ◽

Tumor Bearing ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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