Self-assembled nanosystems as delivery vehicles for regenerative medicine

2012 ◽  
Vol 3 (5) ◽  
pp. 583-587
Author(s):  
Piyush Koria
2021 ◽  
Vol 266 ◽  
pp. 118128
Author(s):  
Mengjie Xu ◽  
Miao Qin ◽  
Yizhu Cheng ◽  
Xiaolian Niu ◽  
Jinlong Kong ◽  
...  

2013 ◽  
Vol 5 (3) ◽  
Author(s):  
Magesh Sadasivam ◽  
Pinar Avci ◽  
Gaurav K. Gupta ◽  
Shanmugamurthy Lakshmanan ◽  
Rakkiyappan Chandran ◽  
...  

AbstractPhotodynamic therapy (PDT) employs the combination of non-toxic photosensitizers (PS) together with harmless visible light of the appropriate wavelength to produce reactive oxygen species that kill unwanted cells. Because many PS are hydrophobic molecules prone to aggregation, numerous drug delivery vehicles have been tested to solubilize these molecules, render them biocompatible and enhance the ease of administration after intravenous injection. The recent rise in nanotechnology has markedly expanded the range of these nanoparticulate delivery vehicles beyond the well-established liposomes and micelles. Self-assembled nanoparticles are formed by judicious choice of monomer building blocks that spontaneously form a well-oriented 3-dimensional structure that incorporates the PS when subjected to the appropriate conditions. This self-assembly process is governed by a subtle interplay of forces on the molecular level. This review will cover the state of the art in the preparation and use of self-assembled liposomal nanoparticles within the context of PDT.


2022 ◽  
pp. 293-325
Author(s):  
Charu Misra ◽  
Rakesh Kumar Paul ◽  
Nagarani Thotakura ◽  
Kaisar Raza

Author(s):  
Samira Asgharzad ◽  
Akram Alizadeh ◽  
Samaneh Arab

Abstract: Regenerative medicine (RM) is an interdisciplinary field that uses different approaches to accelerate the repair and regeneration or replace damaged or diseased human cells or tissues to achieve normal tissue function. These approaches include the stimulation of the body's own repair processes, transplantation of progenitor cells, stem cells, or tissues, as well as the use of cells and exosomes as delivery-vehicles for cytokines, genes, or other therapeutic agents. COVID-19 pneumonia is a specific disease consistent with diffuse alveolar damage resulting in severe hypoxemia. Therefore, the most serious cause of death from COVID-19 is lung dysfunction. Here, we consider RM approaches to cure COVID-19 pneumonia based on what RM has so far used to treat lung diseases, injuries, or pneumonia induced by other pathogens. These approaches include stem and progenitor cell transplantation, stem cell-derived exosomes, and microRNAs therapy.


2015 ◽  
Vol 113 (6) ◽  
pp. 1155-1163 ◽  
Author(s):  
Dilip Thomas ◽  
Diana Gaspar ◽  
Anna Sorushanova ◽  
Gesmi Milcovich ◽  
Kyriakos Spanoudes ◽  
...  

Biomaterials ◽  
2007 ◽  
Vol 28 (31) ◽  
pp. 4652-4666 ◽  
Author(s):  
Barbara P. Chan ◽  
T.Y. Hui ◽  
C.W. Yeung ◽  
J. Li ◽  
I. Mo ◽  
...  

2013 ◽  
Vol 113 (7) ◽  
pp. 4837-4861 ◽  
Author(s):  
Hossein Hosseinkhani ◽  
Po-Da Hong ◽  
Dah-Shyong Yu

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