Recent advances in research of natural and synthetic bioactive quinolines

2015 ◽  
Vol 7 (7) ◽  
pp. 947-967 ◽  
Author(s):  
Po-Yee Chung ◽  
Zhao-Xiang Bian ◽  
Ho-Yuen Pun ◽  
Dessy Chan ◽  
Albert Sun-Chi Chan ◽  
...  
2021 ◽  
Author(s):  
Vipin Kumar Maikhuri ◽  
Ashok K Prasad ◽  
Amitabh Jha ◽  
Smriti Srivastava

Quinoxalines belong to a class of N-heterocycles which are present in a variety of natural and synthetic compounds. They act as a versatile building block in synthesizing novel heterocyclic scaffolds...


Author(s):  
Shirley Nakagaki ◽  
Guilherme Sippel Machado ◽  
João Felipe Stival ◽  
Everton Henrique dos Santos ◽  
Gabriel Machado Silva ◽  
...  

2019 ◽  
Author(s):  
Chem Int

Chalchone is an aromatic ketone and precursors of open chain flavonoids and isoflavonoids present in edible plants and their derivatives have attracted attention due to many potential pharmacological activities. Chalchone are also known as benzalacetophenone and phenyl styryl ketone. Modifications in their structure have offered diverse pharmacological activities that have proven useful for the development of new medicinal agents having improved potency and lesser toxicity. They are also the intermediates in the Auwer's synthesis of flavanoids and in the biosynthesis of flavanoids. Chalchone can be synthesized by various method but the two main methods are Aldol condensation method and Claisen Schmidt method. This review provides an overview of the pharmacological activities of natural and synthetic chalchone derivatives.


2021 ◽  
Vol 37 (6) ◽  
pp. 1280-1286
Author(s):  
Madhuri Suthar ◽  
Jasmin Kumbhani ◽  
Keyur D. Bhatt

2H-pyrans and 4H-pyrans, which are six-membered heterocyclic compounds containing oxygen, are a class of biologically dynamic natural and synthetic products that played a key character in bioorganic chemistry and continue to pique attention. Pyrans and their analogues have a prominent position in bioorganic chemistry because of their numerous applications. This analysis explored the most recent advances, as well as the discovery of new methodologies and the diverse biological activities of pyran analogues.


ChemInform ◽  
2016 ◽  
Vol 47 (18) ◽  
Author(s):  
Po-Yee Chung ◽  
Zhao-Xiang Bian ◽  
Ho-Yuen Pun ◽  
Dessy Chan ◽  
Albert Sun-Chi Chan ◽  
...  

1988 ◽  
Vol 132 ◽  
pp. 525-530
Author(s):  
Raffaele G. Gratton

The use CCD detectors has allowed a major progress in abundance derivations for globular cluster stars in the last years. Abundances deduced from high dispersion spectra now correlates well with other abundance indicators. I discuss some problems concerning the derivation of accurate metal abundances for globular clusters using high dispersion spectra from both the old photographic and the most recent CCD data. The discrepant low abundances found by Cohen (1980), from photographic material for M71 giants, are found to be due to the use of too high microturbulences.


2020 ◽  
Vol 7 (8) ◽  
pp. 1022-1060 ◽  
Author(s):  
Wenbo Ma ◽  
Nikolaos Kaplaneris ◽  
Xinyue Fang ◽  
Linghui Gu ◽  
Ruhuai Mei ◽  
...  

This review summarizes recent advances in C–S and C–Se formations via transition metal-catalyzed C–H functionalization utilizing directing groups to control the site-selectivity.


2021 ◽  
Author(s):  
Manuela Oliverio ◽  
Monica Nardi ◽  
Maria Luisa Di Gioia ◽  
Paola Costanzo ◽  
Sonia Bonacci ◽  
...  

Semi-synthesis is an effective strategy to obtain both natural and synthetic analogues of the olive secoiridoids, starting from easy accessible natural compounds.


2006 ◽  
Vol 73 ◽  
pp. 109-119 ◽  
Author(s):  
Chris Stockdale ◽  
Michael Bruno ◽  
Helder Ferreira ◽  
Elisa Garcia-Wilson ◽  
Nicola Wiechens ◽  
...  

In the 30 years since the discovery of the nucleosome, our picture of it has come into sharp focus. The recent high-resolution structures have provided a wealth of insight into the function of the nucleosome, but they are inherently static. Our current knowledge of how nucleosomes can be reconfigured dynamically is at a much earlier stage. Here, recent advances in the understanding of chromatin structure and dynamics are highlighted. The ways in which different modes of nucleosome reconfiguration are likely to influence each other are discussed, and some of the factors likely to regulate the dynamic properties of nucleosomes are considered.


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