Denture polymers with antimicrobial properties: a review of the development and current status of anionic poly(methyl methacrylate) polymers

2013 ◽  
Vol 5 (14) ◽  
pp. 1635-1645 ◽  
Author(s):  
Periathamby Antony Raj ◽  
Andrew R Dentino
Keyword(s):  
Methyl Methacrylate ◽  
Antimicrobial Properties ◽  
Current Status ◽  
Poly Methyl Methacrylate ◽  
Methacrylate Polymers

scholarly journals Hybrid Nanoparticles of Poly (Methyl Methacrylate) and Antimicrobial Quaternary Ammonium Surfactants

Pharmaceutics ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 340 ◽  
Author(s):  
Beatriz Ideriha Mathiazzi ◽  
Ana Maria Carmona-Ribeiro
Keyword(s):  
Methyl Methacrylate ◽  
Quaternary Ammonium ◽  
Antimicrobial Properties ◽  
Bioactive Molecules ◽  
Hybrid Nanoparticles ◽  
Ammonium Bromide ◽  
Poly Methyl Methacrylate ◽  
Dimethyl Ammonium ◽  
Cetyl Trimethyl Ammonium ◽  
Quaternary Ammonium Surfactants

Quaternary ammonium surfactants (QACs) are microbicides, whereas poly (acrylates) are biocompatible polymers. Here, the physical and antimicrobial properties of two QACs, cetyl trimethyl ammonium bromide (CTAB) or dioctadecyl dimethyl ammonium bromide (DODAB) in poly (methyl methacrylate) (PMMA) nanoparticles (NPs) are compared to those of QACs alone. Methyl methacrylate (MMA) polymerization using DODAB or CTAB as emulsifiers and initiator azobisisobutyronitrile (AIBN) yielded cationic, nanometric, homodisperse, and stable NPs. NPs’ physical and antimicrobial properties were assessed from dynamic light scattering (DLS), scanning electron microscopy, and viability curves of Escherichia coli, Staphylococcus aureus, or Candida albicans determined as log(colony-forming unities counting) over a range of [QACs]. NPs were spherical and homodisperse but activity for free QACs was higher than those for QACs in NPs. Inhibition halos against bacteria and yeast were observed only for free or incorporated CTAB in NPs because PMMA/CTAB NPs controlled the CTAB release. DODAB displayed fungicidal activity against C. albicans since DODAB bilayer disks could penetrate the outer glycoproteins fungus layer. The physical properties and stability of the cationic NPs highlighted their potential to combine with other bioactive molecules for further applications in drug and vaccine delivery.

scholarly journals Effect of Storage in Distilled Water for Three Months on the Antimicrobial Properties of Poly(methyl methacrylate) Denture Base Material Doped with Inorganic Filler

Materials ◽  
2016 ◽  
Vol 9 (5) ◽  
pp. 328 ◽  
Author(s):  
Grzegorz Chladek ◽  
Katarzyna Basa ◽  
Anna Mertas ◽  
Wojciech Pakieła ◽  
Jarosław Żmudzki ◽  
...  
Keyword(s):  
Methyl Methacrylate ◽  
Antimicrobial Properties ◽  
Base Material ◽  
Inorganic Filler ◽  
Distilled Water ◽  
Denture Base ◽  
Poly Methyl Methacrylate

Pilot-scale synthesis and rheological assessment of poly(methyl methacrylate) polymers: Perspectives for medical application

2015 ◽  
Vol 51 ◽  
pp. 107-116 ◽  
Author(s):  
Lamia Zuniga Linan ◽  
Nádson M. Nascimento Lima ◽  
Rubens Maciel Filho ◽  
Marcos A. Sabino ◽  
Mark T. Kozlowski ◽  
...  
Keyword(s):  
Methyl Methacrylate ◽  
Medical Application ◽  
Pilot Scale ◽  
Poly Methyl Methacrylate ◽  
Methacrylate Polymers
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