Bioactive glasses: traditional and prospective applications in healthcare

2014 ◽  
pp. 56-68 ◽  
Author(s):  
Wei Li ◽  
Aldo R Boccaccini
Keyword(s):  
Bioactive Glasses

Analysis of permeability and biological properties of dentin treated with experimental bioactive glasses

2021 ◽  
pp. 103719
Author(s):  
Bruna de Oliveira Reis ◽  
Anuradha Prakki ◽  
Alexander Terry Stavroullakis ◽  
Marina Trevelin Souza ◽  
Renato Luiz Siqueira ◽  
...  
Keyword(s):  
Biological Properties ◽  
Bioactive Glasses

Preparation and in vitro evaluation of Lithium-doped bioactive glasses for wound healing with nerve repair potential

2021 ◽  
Vol 292 ◽  
pp. 129629
Author(s):  
Rong Wei ◽  
Zhaowenbin Zhang ◽  
Min Xing ◽  
Yanling Zhou ◽  
Jiang Chang
Keyword(s):  
Wound Healing ◽  
Nerve Repair ◽  
Bioactive Glasses ◽  
In Vitro Evaluation

scholarly journals DC and AC Conductivity, Biosolubility and Thermal Properties of Mg-Doped Na2O–CaO–P2O5 Glasses

Materials ◽  
2021 ◽  
Vol 14 (10) ◽  
pp. 2626
Author(s):  
Natalia Anna Wójcik ◽  
Sharafat Ali ◽  
Jakub Lech Karczewski ◽  
Bo Jonson ◽  
Michał Bartmański ◽  
...  
Keyword(s):  
Thermal Properties ◽  
Saline Solution ◽  
Glass Structure ◽  
Glass Network ◽  
Bioactive Glasses ◽  
Dc And Ac Conductivity ◽  
Impedance Spectroscopy Technique ◽  
Mg Content ◽  
Phosphate Buffered Saline ◽  
Mg Doped

Bioactive glasses have recently been extensively used to replace, regenerate, and repair hard tissues in the human body because of their ability to bond with living tissue. In this work, the effects of replacing Na2O with MgO on the electrical, biosolubility, and thermal properties of the target glass 10Na2O–60P2O5–30CaO (in mol%) were investigated. The electrical properties of the glasses were studied with the impedance spectroscopy technique. At 473 K, DC conductivity values decreased from 4.21 × 10−11 to 4.21 × 10−12 S cm−1 after complete substitution of MgO for Na2O. All samples had a similar activation energy of the DC conduction process ~1.27 eV. Conduction mechanisms were found to be due to hop of ions: Na+, Mg2+, and probable H+. FTIR analysis showed that, as the Mg content increased, the Q2 unit (PO2−) shifted towards higher wavenumbers. The proportion of Q3 unit (P2O5) decreased in the glass structure. This confirmed that the replacement of Na+ by Mg2+ was accompanied by concurrent polymerization of the calcium–phosphate glass network. The biosolubility test in the phosphate-buffered saline solution showed that the magnesium addition enhanced the biosolubility properties of Na2O–CaO–P2O5 glasses by increasing their dissolution rate and supporting forming CaP-rich layers on the surface. The glass transition temperature increased, and thermal stability decreased substantially upon substitution of Na2O by MgO.

scholarly journals Mesoporous Silica Nanoparticles and Mesoporous Bioactive Glasses for Wound Management: From Skin Regeneration to Cancer Therapy

Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3337
Author(s):  
Sara Hooshmand ◽  
Sahar Mollazadeh ◽  
Negar Akrami ◽  
Mehrnoosh Ghanad ◽  
Ahmed El-Fiqi ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Skin Regeneration ◽  
Bioactive Molecules ◽  
Wound Management ◽  
Bioactive Glasses ◽  
Wide Range

Exploring new therapies for managing skin wounds is under progress and, in this regard, mesoporous silica nanoparticles (MSNs) and mesoporous bioactive glasses (MBGs) offer great opportunities in treating acute, chronic, and malignant wounds. In general, therapeutic effectiveness of both MSNs and MBGs in different formulations (fine powder, fibers, composites etc.) has been proved over all the four stages of normal wound healing including hemostasis, inflammation, proliferation, and remodeling. The main merits of these porous substances can be summarized as their excellent biocompatibility and the ability of loading and delivering a wide range of both hydrophobic and hydrophilic bioactive molecules and chemicals. In addition, doping with inorganic elements (e.g., Cu, Ga, and Ta) into MSNs and MBGs structure is a feasible and practical approach to prepare customized materials for improved skin regeneration. Nowadays, MSNs and MBGs could be utilized in the concept of targeted therapy of skin malignancies (e.g., melanoma) by grafting of specific ligands. Since potential effects of various parameters including the chemical composition, particle size/morphology, textural properties, and surface chemistry should be comprehensively determined via cellular in vitro and in vivo assays, it seems still too early to draw a conclusion on ultimate efficacy of MSNs and MBGs in skin regeneration. In this regard, there are some concerns over the final fate of MSNs and MBGs in the wound site plus optimal dosages for achieving the best outcomes that deserve careful investigation in the future.

scholarly journals Tantalum doped SiO2-CaO-P2O5 based bioactive glasses: Investigation of in vitro bioactivity and antibacterial activities

2020 ◽  
Vol 6 (1) ◽  
pp. 10-22
Author(s):  
Zakaria Tabia ◽  
Sihame Akhtach ◽  
Khalil El Mabrouk ◽  
Meriame Bricha ◽  
Khalid Nouneh ◽  
...  
Keyword(s):  
Antibacterial Activities ◽  
Silica Matrix ◽  
Morphological Properties ◽  
Metallic Ions ◽  
X Ray Diffraction ◽  
Bioactive Glasses ◽  
E Coli ◽  
Fourier Transformed Infrared Spectroscopy ◽  
Electron Scanning Microscopy

AbstractMultifunctionality can be achieved for bioactive glasses by endowing them with multiple other properties along with bioactivity. One way to address this topic is by doping these glasses with therapeutic metallic ions. In this work, we put under investigation a series of bioactive glasses doped with tantalum. We aim to study the effect of tantalum, on the structure, bioactivity and antibacterial property of a ternary bioactive glass composition based on SiO2-CaO-P2O5. Fourier Transformed Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD) and Electron Scanning Microscopy (SEM) were used to assess the structural and morphological properties of these glasses and monitor their changes after in vitro acellular bioactivity test. Antibacterial activity was tested against gram positive and negative bacteria. Characterization results confirmed the presence of calcium carbonate crystallites along with the amorphous silica matrix. The assessment of bioactivity in SBF indicated that all compositions showed a fast bioactive response after only six hours of immersion period. However, analytical characterization revealed that tantalum introduced a slight latency in hydroxyapatite deposition at higher concentrations (0.8-1 %mol). Antibacterial test showed that tantalum ions had an inhibition effect on the growth of E. coli and S. aureus. This effect was more pronounced in compositions where mol% of tantalum is superior to 0.4%. These results proved that tantalum could be used, in intermediate proportions, as a promising multifunctional dopant element in bioactive glasses for bone regeneration applications.

Bioactive glasses—structure and applications

2019 ◽  
pp. 453-476
Author(s):  
Imran Farooq ◽  
Saqib Ali ◽  
Shehriar Husain ◽  
Erum Khan ◽  
Robert G. Hill
Keyword(s):  
Bioactive Glasses

Preparation and In Vitro Behavior of Bioactive Glasses from Bovine Waste Resource

2006 ◽  
Vol 309-311 ◽  
pp. 329-332
Author(s):  
S.H. Ahn ◽  
Yong Nam Kim ◽  
Hyun Gyu Shin ◽  
Hee Soo Lee ◽  
Jong Hee Hwang ◽  
...  
Keyword(s):  
High Purity ◽  
Alternative Strategy ◽  
Biological Resource ◽  
Bioactive Glasses ◽  
Sio2 System ◽  
Functional Applications

Preparation of bioactive glasses was attempted utilizing waste bovine as raw resource. Bioactive and biodegradable batch compositions in the Na2O-CaO-SiO2 system were included with calcined bovine, whose phase was high-purity oxy-hydroxyapatite. Bovine inclusion as large as 40 mass% was shown to present highly bioactive glasses; bovine in the bioactive and biodegradable compositions presented glasses with controlled bioactivity and biodegradability, respectively. These indicate not only a plenty biological resource of bio-interactive materials, but also an alternative strategy for bioactive glasses with multi-functional applications.

Bioactivity and biocompatibility of two fluoride containing bioactive glasses for dental applications

2016 ◽  
Vol 32 (11) ◽  
pp. 1414-1428 ◽  
Author(s):  
T. De Caluwé ◽  
C.W.J. Vercruysse ◽  
H.A. Declercq ◽  
D. Schaubroeck ◽  
R.M.H. Verbeeck ◽  
...  
Keyword(s):  
Bioactive Glasses ◽  
Dental Applications
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