Clinical trials to prevent/treat childhood asthma: methodologic issues

2014 ◽  
Vol 4 (11) ◽  
pp. 1001-1004 ◽  
Author(s):  
Scott T Weiss ◽  
Augusto A Litonjua
Keyword(s):  
Clinical Trials ◽  
Childhood Asthma

The need for precision medicine clinical trials in childhood asthma: rationale and design of the PUFFIN trial

2017 ◽  
Vol 18 (4) ◽  
pp. 393-401 ◽  
Author(s):  
Susanne JH Vijverberg ◽  
Mariëlle W Pijnenburg ◽  
Anke M Hövels ◽  
Gerard H Koppelman ◽  
Anke-Hilse Maitland-van der Zee
Keyword(s):  
Clinical Trials ◽  
Precision Medicine ◽  
Childhood Asthma

scholarly journals Childhood asthma clusters and response to therapy in clinical trials

2014 ◽  
Vol 133 (2) ◽  
pp. 363-369.e3 ◽  
Author(s):  
Timothy S. Chang ◽  
Robert F. Lemanske ◽  
David T. Mauger ◽  
Anne M. Fitzpatrick ◽  
Christine A. Sorkness ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Childhood Asthma ◽  
Response To Therapy

Localization of Gallium-67 in Peritoneal Cells by Electron Microscopic Autoradiography

1973 ◽  
Vol 31 ◽  
pp. 404-405
Author(s):  
D. C. Swartzendruber ◽  
Norma L. Idoyaga-Vargas
Keyword(s):  
Clinical Trials ◽  
Soft Tissue ◽  
Tumor Tissue ◽  
Soft Tissue Tumors ◽  
Clinical Usefulness ◽  
Electron Microscopic ◽  
Normal Cells ◽  
Electron Microscopic Autoradiography ◽  
Peritoneal Cells ◽  
Gallium 67

The radionuclide gallium-67 (67Ga) localizes preferentially but not specifically in many human and experimental soft-tissue tumors. Because of this localization, 67Ga is used in clinical trials to detect humar. cancers by external scintiscanning methods. However, the fact that 67Ga does not localize specifically in tumors requires for its eventual clinical usefulness a fuller understanding of the mechanisms that control its deposition in both malignant and normal cells. We have previously reported that 67Ga localizes in lysosomal-like bodies, notably, although not exclusively, in macrophages of the spocytaneous AKR thymoma. Further studies on the uptake of 67Ga by macrophages are needed to determine whether there are factors related to malignancy that might alter the localization of 67Ga in these cells and thus provide clues to discovering the mechanism of 67Ga localization in tumor tissue.

Rome I versus Rome II; Overlap in patients enrolled in tegaserod phase III clinical trials for irritable bowel syndrome (IBS)

2001 ◽  
Vol 120 (5) ◽  
pp. A284-A284
Author(s):  
B NAULT ◽  
S SUE ◽  
J HEGGLAND ◽  
S GOHARI ◽  
G LIGOZIO ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Irritable Bowel Syndrome ◽  
Phase Iii ◽  
Phase Iii Clinical Trials ◽  
Irritable Bowel ◽  
Rome I
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