scholarly journals Expression of orphan GPR56 correlates with tumor progression in human epithelial ovarian cancer

Neoplasma ◽  
2017 ◽  
Vol 64 (01) ◽  
pp. 32-39 ◽  
Author(s):  
Z. LIU ◽  
Z. HUANG ◽  
W. YANG ◽  
Z. LI ◽  
S. XING ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Tumor Progression

scholarly journals Overexpression of Runt-Related Transcription Factor-2 Is Associated with Advanced Tumor Progression and Poor Prognosis in Epithelial Ovarian Cancer

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Weiping Li ◽  
Shujuan Xu ◽  
Shuang Lin ◽  
Wei Zhao
Keyword(s):  
Ovarian Cancer ◽  
Transcription Factor ◽  
Clinical Outcome ◽  
Epithelial Ovarian Cancer ◽  
Tumor Progression ◽  
Clinical Stage ◽  
Runx2 Expression ◽  
Advanced Tumor ◽  
Clinical Stages ◽  
Related Transcription Factor

Aim. To investigate clinical significance of runt-related transcription factor (RUNX)-2 in epithelial ovarian cancer (EOC).Methods. RUNX2 protein expression and its subcellular localization were detected by immunohistochemistry in 116 patients with EOC.Results. RUNX2 protein was predominantly expressed in cell nucleus of EOC tissues. The expression level of RUNX2 in EOC tissues was significantly higher than that in normal ovarian tissues(P<0.001). In addition, the nuclear labeling index (LI) of RUNX2 in tumor cells was significantly associated with the advanced clinical stage of EOC tissues(P=0.001). Moreover, EOC patients with high RUNX2 LI had significantly shorter overall(P<0.001)and progression-free(P=0.002)survival than those with low RUNX2 LI. Especially, subgroup analysis revealed that EOC patients with high clinical stages (III~IV) in high RUNX2 expression group demonstrated a significantly worse clinical outcome than those in low RUNX2 expression group, but patients with low clinical stages (I~II) had no significantly different prognosis between high and low RUNX2 expression groups.Conclusions. Our data suggest for the first time that RUNX2 overexpression is associated with advanced tumor progression and poor clinical outcome of EOC patients. RUNX2 might be a novel prognostic marker of EOC.

scholarly journals Expression of stress-induced phosphoprotein1 (STIP1) is associated with tumor progression and poor prognosis in epithelial ovarian cancer

2014 ◽  
Vol 53 (4) ◽  
pp. 277-288 ◽  
Author(s):  
Hanbyoul Cho ◽  
Sunghoon Kim ◽  
Ha-Yeon Shin ◽  
Eun Joo Chung ◽  
Haruhisa Kitano ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Tumor Progression ◽  
Poor Prognosis

Upregulation of microRNA-203 is associated with advanced tumor progression and poor prognosis in epithelial ovarian cancer

2013 ◽  
Vol 30 (3) ◽  
Author(s):  
Shaosheng Wang ◽  
Xiaohong Zhao ◽  
Jie Wang ◽  
Yingmei Wen ◽  
LinJing Zhang ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Tumor Progression ◽  
Poor Prognosis ◽  
Advanced Tumor

scholarly journals Galectin-1 promotes tumor progression via NF-κB signaling pathway in epithelial ovarian cancer

2017 ◽  
Vol 8 (18) ◽  
pp. 3733-3741 ◽  
Author(s):  
Le Chen ◽  
Ying Yao ◽  
Lijuan Sun ◽  
Jie Tang
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Tumor Progression ◽  
Signaling Pathway

Expression of 67-kDa laminin receptor was associated with tumor progression and poor prognosis in epithelial ovarian cancer

2012 ◽  
Vol 125 (2) ◽  
pp. 427-432 ◽  
Author(s):  
Taejong Song ◽  
Chel Hun Choi ◽  
Young Jae Cho ◽  
Chang Ohk Sung ◽  
Sang Yong Song ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Tumor Progression ◽  
Poor Prognosis ◽  
Laminin Receptor

PRSS3 expression is associated with tumor progression and poor prognosis in epithelial ovarian cancer

2015 ◽  
Vol 137 (3) ◽  
pp. 546-552 ◽  
Author(s):  
Ruiqiong Ma ◽  
Xue Ye ◽  
Hongyan Cheng ◽  
Yu Ma ◽  
Heng Cui ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Tumor Progression ◽  
Poor Prognosis
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