scholarly journals Effect of the allopregnanolone and allotetrahydrodeoxycorticosteron on spike-wave discharges in the EEG of absence epilepsy rat models

2018 ◽  
Vol 37 (02) ◽  
pp. 205-211 ◽  
Author(s):  
Sebahattin Karabulut ◽  
Ruslan Bayramov ◽  
Keziban Korkmaz Bayramov ◽  
Ahmet K. Filiz ◽  
Ahmet S. Taskiran ◽  
...  
Keyword(s):  
Absence Epilepsy ◽  
Rat Models ◽  
Spike Wave Discharges ◽  
Spike Wave

scholarly journals Co-existence of Rolandic and 3 Hz Spike-Wave Discharges on EEG in Children with Epilepsy

2018 ◽  
Vol 46 (1) ◽  
pp. 64-70 ◽  
Author(s):  
Anita N. Datta ◽  
Laura Wallbank ◽  
Peter K. H. Wong
Keyword(s):  
Clinical Data ◽  
Seizure Control ◽  
Age Of Onset ◽  
Absence Epilepsy ◽  
Childhood Absence Epilepsy ◽  
Drug Induced ◽  
Favorable Prognosis ◽  
Spike Wave Discharges ◽  
Spike Wave

AbstractObjectiveBenign epilepsy of childhood with central temporal spikes (BECTS) and absence epilepsy are common epilepsy syndromes in children with similar age of onset and favorable prognosis. However, the co-existence of the electrocardiogram (EEG) findings of rolandic spike and 3 Hz generalized spike-wave (GSW) discharges is extremely rare, with few cases reported in the literature. Our objective was to characterize the EEG findings of these syndromes in children in our center and review the electro-clinical features.MethodsAll EEGs at BC Children’s Hospital are entered in a database, which include EEG findings and clinical data. Patients with both centro-temporal spikes and 3 Hz GSW discharges were identified from the database and clinical data were reviewed.ResultsAmong the 43,061 patients in the database from 1992 to 2017, 1426 with isolated rolandic discharges and 528 patients with isolated 3 Hz GSW discharges were identified, and 20 (0.05%) patients had both findings: 3/20 had BECTS, and subsequently developed childhood absence epilepsy and 17/20 had no seizures characteristic for BECTS. At follow-up, 17 (85%) were seizure-free, 1 (5%) had rare, and 2 (10%) had frequent seizures.ConclusionsThis is the largest reported group of patients to our knowledge with the co-existence of rolandic and 3 Hz GSW discharges on EEGs in one institution, not drug-induced. As the presence of both findings is extremely rare, distinct pathophysiological mechanisms are likely. The majority had excellent seizure control at follow-up, similar to what would be expected for each type of epilepsy alone.

Finasteride inhibits the progesterone-induced spike-wave discharges in a genetic model of absence epilepsy

2003 ◽  
Vol 75 (4) ◽  
pp. 889-894 ◽  
Author(s):  
Gilles van Luijtelaar ◽  
Bogusława Budziszewska ◽  
Magdalena Tetich ◽  
Władysław Lasoń
Keyword(s):  
Genetic Model ◽  
Absence Epilepsy ◽  
Spike Wave Discharges ◽  
Spike Wave

The 5-HT1A agonist 8-OH-DPAT increases the number of spike-wave discharges in a genetic rat model of absence epilepsy

1998 ◽  
Vol 807 (1-2) ◽  
pp. 243-245 ◽  
Author(s):  
Katalin Gerber ◽  
Janos Filakovszky ◽  
Peter Halasz ◽  
Gyorgy Bagdy
Keyword(s):  
Rat Model ◽  
Absence Epilepsy ◽  
Spike Wave Discharges ◽  
Spike Wave

scholarly journals Generalized spike-wave discharges involve a default mode network in patients with juvenile absence epilepsy: A MEG study

2010 ◽  
Vol 89 (2-3) ◽  
pp. 176-184 ◽  
Author(s):  
Kotaro Sakurai ◽  
Youji Takeda ◽  
Naoaki Tanaka ◽  
Tsugiko Kurita ◽  
Hideaki Shiraishi ◽  
...  
Keyword(s):  
Default Mode Network ◽  
Absence Epilepsy ◽  
Default Mode ◽  
Spike Wave Discharges ◽  
Juvenile Absence Epilepsy ◽  
Spike Wave

Information processing during cortical spike-wave discharges in rats with absence epilepsy: Effects of stimulus impact

1993 ◽  
Vol 29 (1-2) ◽  
pp. 144-145
Author(s):  
Rian Schuurmans ◽  
Pim Drinkenburg ◽  
Anton Coenen ◽  
Gilles van Luijtelaar
Keyword(s):  
Information Processing ◽  
Absence Epilepsy ◽  
Spike Wave Discharges ◽  
Spike Wave

EEG–fMRI study on the interictal and ictal generalized spike-wave discharges in patients with childhood absence epilepsy

2009 ◽  
Vol 87 (2-3) ◽  
pp. 160-168 ◽  
Author(s):  
Qifu Li ◽  
Cheng Luo ◽  
Tianhua Yang ◽  
Zhiping Yao ◽  
Li He ◽  
...  
Keyword(s):  
Absence Epilepsy ◽  
Childhood Absence Epilepsy ◽  
Fmri Study ◽  
Spike Wave Discharges ◽  
Spike Wave
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