scholarly journals Imaging of striatal injury in a songbird brain

2017 ◽  
Vol 36 (01) ◽  
pp. 23-27 ◽  
Author(s):  
Kristina Lukacova ◽  
Ladislav Baciak ◽  
Eva Pavukova ◽  
Katarina Pichova ◽  
Svatava Kasparova ◽  
...  
Keyword(s):  
Striatal Injury

Sprouting of Dopaminergic Axons after Striatal Injury: Confirmation by Markers Not Dependent on Dopamine Metabolism

1999 ◽  
Vol 159 (2) ◽  
pp. 565-573 ◽  
Author(s):  
G.T. Liberatore ◽  
D.I. Finkelstein ◽  
J.Y.F. Wong ◽  
M.K. Horne ◽  
M.J. Porritt ◽  
...  
Keyword(s):  
Dopamine Metabolism ◽  
Striatal Injury

Role of nitric oxide in rotenone-induced nigro-striatal injury

2003 ◽  
Vol 86 (6) ◽  
pp. 1338-1345 ◽  
Author(s):  
Yi He ◽  
Syed Z. Imam ◽  
Zaojun Dong ◽  
Joseph Jankovic ◽  
Syed F. Ali ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Striatal Injury

Patterns, evolution, and severity of striatal injury in insidious‐ vs acute‐onset glutaric aciduria type 1

2019 ◽  
Vol 42 (1) ◽  
pp. 117-127 ◽  
Author(s):  
Nikolas Boy ◽  
Sven F. Garbade ◽  
Jana Heringer ◽  
Angelika Seitz ◽  
Stefan Kölker ◽  
...  
Keyword(s):  
Acute Onset ◽  
Glutaric Aciduria Type ◽  
Glutaric Aciduria Type 1 ◽  
Glutaric Aciduria ◽  
Striatal Injury

scholarly journals Minocycline treatment reduces white matter damage after excitotoxic striatal injury

2010 ◽  
Vol 1329 ◽  
pp. 182-193 ◽  
Author(s):  
Joanilson S. Guimarães ◽  
Marco Aurelio M. Freire ◽  
Rafael R. Lima ◽  
Cristovam W. Picanço-Diniz ◽  
Antonio Pereira ◽  
...  
Keyword(s):  
White Matter ◽  
White Matter Damage ◽  
Minocycline Treatment ◽  
Striatal Injury

Role of dopamine in ischemic striatal injury: Metabolic evidence

Neurology ◽  
1987 ◽  
Vol 37 (11) ◽  
pp. 1712-1712 ◽  
Author(s):  
M. Y.-T. Globus ◽  
M. D. Ginsberg ◽  
S. I. Harik ◽  
R. Busto ◽  
W. D. Dietrich
Keyword(s):  
Striatal Injury

Preliminary attempts to establish a rat model of striatal injury in glutaric acidaemia type I

2004 ◽  
Vol 27 (6) ◽  
pp. 819-824 ◽  
Author(s):  
C. B. R. Funk ◽  
A. N. Prasad ◽  
M. R. Del Bigio
Keyword(s):  
Rat Model ◽  
Type I ◽  
Striatal Injury

scholarly journals Male-Specific Alleviation of Iron-Induced Striatal Injury by Inhibition of Autophagy

PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0131224 ◽  
Author(s):  
Li-Fang Wang ◽  
Kazunari K. Yokoyama ◽  
Tzu-Yin Chen ◽  
Hsiu-Wen Hsiao ◽  
Pei-Chi Chiang ◽  
...  
Keyword(s):  
Male Specific ◽  
Striatal Injury

scholarly journals Neuroprotective effect of ACTH on collagenase-induced peri-intraventricular hemorrhage in newborn male rats

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Camila A. Martins ◽  
Laura Tartari Neves ◽  
Marina M. B. P. de Oliveira ◽  
Pamela Brambilla Bagatini ◽  
Rafaela Barboza ◽  
...  
Keyword(s):  
Intraventricular Hemorrhage ◽  
Neuroprotective Effect ◽  
Brain Lesion ◽  
Male Rats ◽  
Related Complication ◽  
Germinal Matrix ◽  
Striatal Lesion ◽  
Neuroprotective Actions ◽  
Periventricular Area ◽  
Striatal Injury

Abstract Peri-intraventricular hemorrhage (PIVH) is a common and serious prematurity-related complication in neonates. Adrenocorticotropic hormone (ACTH) has neuroprotective actions and is a candidate to ameliorate brain damage following PIVH. Here, we tested the efficacy of ACTH1-24 on a collagenase-induced lesion of the germinal matrix (GM) in newborn male rats. Animals received microinjection of the vehicle (PBS, 2 µl) or collagenase type VII (0.3 IU) into the GM/periventricular tissue on postnatal day (PN) 2. Twelve hours later pups received microinjection of either the agonist ACTH1-24 (0.048 mg/kg), or the antagonist SHU9119 (antagonist of MCR3/MCR4 receptors, 0.01 mg/kg), or their combination. Morphological outcomes included striatal injury extension, neuronal and glial cells counting, and immunohistochemical expression of brain lesion biomarkers ipsilateral and contralateral to the hemorrhagic site. Data were evaluated on PN 8. Collagenase induced PIVH and severe ipsilateral striatal lesion. ACTH1-24 dampened the deleterious effects of collagenase-induced hemorrhage in significantly reducing the extension of the damaged area, the striatal neuronal and glial losses, and the immunoreactive expression of the GFAP, S100β, and NG2-glia biomarkers in the affected periventricular area. SHU9119 blocked the glial density rescuing effect of ACTH1-24. ACTH1-24 could be further evaluated to determine its suitability for preclinical models of PVH in premature infants.

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