scholarly journals Grape-seed polyphenols inhibit AAA in mice via regulation of macrophage polarization

2020 ◽  
Vol 121 (09) ◽  
pp. 680-685
Author(s):  
D. Ma ◽  
H. T. Shen ◽  
J. J. Zhao ◽  
Q. Chang ◽  
L. B. Tian ◽  
...  
Author(s):  
Faizan Kalekhan ◽  
Nandakishore Bala ◽  
Suresh Rao ◽  
Michael L.J. Pais ◽  
Mohammed Adnan ◽  
...  

2011 ◽  
Vol 129 (2) ◽  
pp. 570-576 ◽  
Author(s):  
Yinping Li ◽  
George K. Skouroumounis ◽  
Gordon M. Elsey ◽  
Dennis K. Taylor

OENO One ◽  
1985 ◽  
Vol 19 (2) ◽  
pp. 73
Author(s):  
Gérard Darné ◽  
Jacques Bouard

<p style="text-align: justify;">Les incisions annulaires provoquent une modification de la teneur en polyphénols des pépins. Les résultats obtenus avec une double incision suggèrent qu'il existe une compétition entre le métabolisme polyphénolique des pépins qui accumulent des tanins proanthocyanidiques et le métabolisme anthocyanique des baies.</p><p style="text-align: justify;">+++</p><p style="text-align: justify;">Girdling leads to a modification in the polyphenol's content of grape seeds. The results obtained with a double girdle suggest the existence of a competition between the metabolism of the grape seed polyphenols, which accumulate proanthocyanidic tannins, and the anthocyanic metabolism of berries.</p>


Author(s):  
Manjeshwar Poonam Baliga Rao ◽  
Raghavendra Haniadka ◽  
Karadka Ramdas Thilakchand ◽  
Princy Louis Palatty ◽  
Manjeshwar Shrinath Baliga

2017 ◽  
Vol 117 (2) ◽  
pp. 200-208 ◽  
Author(s):  
Zara Pons ◽  
Maria Margalef ◽  
Francisca I. Bravo ◽  
Anna Arola-Arnal ◽  
Begoña Muguerza

AbstractThe effects of grape-seed polyphenols against the development of hypertension and other cardiometabolic conditions associated with the metabolic syndrome (MetS) were studied in rats fed a high-fat, high-carbohydrate diet, known as the cafeteria (CAF) diet. Two groups of Wistar rats were fed standard (STD) or CAF diets for 12 weeks. The CAF diet-fed rats were administered different doses of a low-molecular-weight grape-seed polyphenol extract (LM-GSPE) (25, 100 and 200 mg/kg per d) or vehicle daily, and the STD diet-fed rats were administered LM-GSPE (100 mg/kg per d) or vehicle using ten animals per group. Body weight (BW), waist perimeter (WP) and systolic and diastolic blood pressures (BP) by the tail-cuff method were recorded weekly. The animals were housed in metabolic chambers every 2 weeks to estimate daily food and liquid intakes and to collect faeces and urine samples. The plasma lipid profile was analysed at time 0 and on the 4th, 7th, 10th and 12th weeks of the experiment. Moreover, plasma leptin was measured at the end of the experiment. Results demonstrated that LM-GSPE, when administered with the CAF diet, attenuated the increase in BP, BW, WP and improved lipid metabolism in these animals. However, although the 25- and 100-mg/kg per d doses were sufficient to produce beneficial effects on BP and lipid metabolism, a 200-mg/kg per d dose was necessary to have an effect on BW and WP. The present findings suggest that LM-GSPE is a good candidate for a BP-lowering agent that can also ameliorate other conditions associated with the MetS.


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