scholarly journals High prevalence of norovirus GII.P16/GII.2 and chicken anemia virus in two acute gastroenteritis outbreaks in Huzhou, China

2019 ◽  
Vol 63 (03) ◽  
pp. 328-332
Author(s):  
Y. LI ◽  
P. ZHANG ◽  
X. WU ◽  
D. WEN ◽  
L. JI ◽  
...  
Keyword(s):  
Acute Gastroenteritis ◽  
Chicken Anemia Virus ◽  
High Prevalence ◽  
Anemia Virus

scholarly journals Molecular Properties, Biology, and Clinical Implications of TT Virus, a Recently Identified Widespread Infectious Agent of Humans

2001 ◽  
Vol 14 (1) ◽  
pp. 98-113 ◽  
Author(s):  
Mauro Bendinelli ◽  
Mauro Pistello ◽  
Fabrizio Maggi ◽  
Claudia Fornai ◽  
Giulia Freer ◽  
...  
Keyword(s):  
Virus Detection ◽  
Infectious Agent ◽  
Representational Difference Analysis ◽  
Chicken Anemia Virus ◽  
Remarkable Feature ◽  
Tt Virus ◽  
High Prevalence ◽  
Cryptogenic Hepatitis ◽  
Anemia Virus ◽  
Apparently Healthy

SUMMARY TT virus (TTV) was first described in 1997 by representational difference analysis of sera from non-A to non-G posttransfusion hepatitis patients and hence intensively investigated as a possible addition to the list of hepatitis-inducing viruses. The TTV genome is a covalently closed single-stranded DNA of approximately 3.8 kb with a number of characteristics typical of animal circoviruses, especially the chicken anemia virus. TTV is genetically highly heterogeneous, which has led investigators to group isolates into numerous genotypes and subtypes and has limited the sensitivity of many PCR assays used for virus detection. The most remarkable feature of TTV is the extraordinarily high prevalence of chronic viremia in apparently healthy people, up to nearly 100% in some countries. The original hypothesis that it might be an important cause of cryptogenic hepatitis has not been borne out, although the possibility that it may produce liver damage under specific circumstances has not been excluded. The virus has not yet been etiologically linked to any other human disease. Thus, TTV should be considered an orphan virus.

scholarly journals A third gyrovirus species in human faeces

2012 ◽  
Vol 93 (6) ◽  
pp. 1356-1361 ◽  
Author(s):  
Tung G. Phan ◽  
Linlin Li ◽  
Miguel G. O’Ryan ◽  
Hector Cortes ◽  
Nora Mamani ◽  
...  
Keyword(s):  
Metagenomic Analysis ◽  
Chicken Anemia Virus ◽  
Human Pathogens ◽  
Human Faeces ◽  
Healthy Humans ◽  
The Family ◽  
High Prevalence ◽  
Anemia Virus

Until 2011 the genus Gyrovirus in the family Circoviridae consisted of a single virus (Chicken anemia virus or CAV) causing a common immunosuppressive disease in chickens when a second gyrovirus (HGyV) was reported on the skin of 4 % of healthy humans. HGyV is very closely related to a recently described chicken gyrovirus, AGV2, suggesting that they belong to the same viral species. During a viral metagenomic analysis of 100 human faeces from children with diarrhoea in Chile we identified multiple known human pathogens (adenoviruses, enteroviruses, astroviruses, sapoviruses, noroviruses, parechoviruses and rotaviruses) and a novel gyrovirus species we named GyV3 sharing <63 % similarity with other gyrovirus proteins with evidence of recombination with CAV in its UTR. Gyroviridae consensus PCR revealed a high prevalence of CAV DNA in diarrhoea and normal faeces from Chilean children and faeces of USA cats and dogs, which may reflect consumption of CAV-infected/vaccinated chickens. Whether GyV3 can infect humans and/or chickens requires further studies.

Molecular epidemiology of norovirus from patients with acute gastroenteritis in northwestern Spain

2014 ◽  
Vol 143 (2) ◽  
pp. 316-324 ◽  
Author(s):  
C. F. MANSO ◽  
J. L. ROMALDE
Keyword(s):  
Phylogenetic Analysis ◽  
Molecular Epidemiology ◽  
Genetic Drift ◽  
Acute Gastroenteritis ◽  
Age Groups ◽  
Capsid Gene ◽  
High Prevalence ◽  
High Incidence ◽  
Northwestern Spain

SUMMARYThe high incidence of norovirus (NoV) infections seems to be related to the emergence of new variants that evolved by genetic drift of the capsid gene. In this work, that represents a first effort to describe the molecular epidemiology of NoV in the northwest of Spain, a total of eight different NoV genotypes (GII.1, GII.3, GII.4, GII.6, GII.7, GII.12, GII.13, GII.14) were detected. The major genotypes observed were GII.4 (45·42%) and GII.14 (34·9%), being detected in all age groups. In addition, and although most of GII.4 sequences belonged to 2006b (7·2%) and 2010 (50·35%) variants, the presence of new NoV variants was observed. Phylogenetic analysis revealed that a high number of GII.4 sequences (35·24%) could be assigned to the newly emerging Sydney 2012 variant, even during late 2010. The high prevalence of NoV GII.14 observed in this study may indicate the emergence of this genotype in Spain.

scholarly journals Performance comparison between broilers positive and negative for antibodies against the chicken anemia virus

2003 ◽  
Vol 34 ◽  
pp. 88-89
Author(s):  
Lauricio Librelotto Rubin ◽  
Luiz Antônio Faccenda de Ávila ◽  
Andréa Machado Leal Ribeiro ◽  
Vera Wald ◽  
Cláudio Wageck Canal
Keyword(s):  
Performance Comparison ◽  
Chicken Anemia Virus ◽  
Anemia Virus

scholarly journals Positive and Negative Regulation of Chicken Anemia Virus Transcription

2005 ◽  
Vol 79 (5) ◽  
pp. 2859-2868 ◽  
Author(s):  
Myrna M. Miller ◽  
Keith W. Jarosinski ◽  
Karel A. Schat
Keyword(s):  
Estrogen Receptor ◽  
Nuclear Receptor ◽  
Protein Translation ◽  
Chicken Anemia Virus ◽  
Egfp Expression ◽  
Start Site ◽  
Response Element ◽  
Nuclear Receptor Superfamily ◽  
Promoter Construct ◽  
Anemia Virus

ABSTRACT Chicken anemia virus (CAV) is a small circular single-stranded DNA virus with a single promoter-enhancer region containing four consensus cyclic AMP response element sequences (AGCTCA), which are similar to the estrogen response element (ERE) consensus half-sites (A)GGTCA. These sequences are arranged as direct repeats, an arrangement that can be recognized by members of the nuclear receptor superfamily. Transient-transfection assays which use a short CAV promoter construct that ended at the transcription start site and drive expression of enhanced green fluorescent protein (EGFP) showed high basal activity in DF-1, LMH, LMH/2A, and primary theca and granulosa cells. The estrogen receptor-enhanced cell line, LMH/2A, had significantly greater expression than LMH cells, and this expression was significantly increased with estrogen treatment. A long promoter construct which included GGTCA-like sequences downstream of the first CAV protein translation start site was found to have significantly less EGFP expression in DF-1 cells than the short promoter, which was largely due to decreased RNA transcription. DNA-protein binding assays indicated that proteins recognizing a consensus ERE palindrome also bind GGTCA-like sequences in the CAV promoter. Estrogen receptor and other members of the nuclear receptor superfamily may provide a mechanism to regulate CAV activity in situations of low virus copy number.

Genome sequencing analysis of Brazilian chicken anemia virus isolates that lack MSB-1 cell culture tropism

2007 ◽  
Vol 30 (2) ◽  
pp. 81-96 ◽  
Author(s):  
Eliana Ottati Nogueira ◽  
Antonio J Piantino Ferreira ◽  
Rodrigo Martins Soares ◽  
Edison Luiz Durigon ◽  
Simaia Lazzarin ◽  
...  
Keyword(s):  
Cell Culture ◽  
Genome Sequencing ◽  
Chicken Anemia Virus ◽  
Sequencing Analysis ◽  
Anemia Virus ◽  
Virus Isolates

scholarly journals Pathogenicity and immunosuppressive potential of an Egyptian field isolate (2015) of the chicken anemia virus (CAV) in chickens

2017 ◽  
Vol 24 (1) ◽  
pp. 103-113
Author(s):  
Nassif S.A. ◽  
Anhar A. Abdel Latif ◽  
Nermeen M. Elsayed ◽  
Hayam Farouk ◽  
Ekram Salama ◽  
...  
Keyword(s):  
Field Isolate ◽  
Chicken Anemia Virus ◽  
Anemia Virus
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