scholarly journals Genetic diversity of 2006–2009 Chikungunya virus outbreaks in Andhra Pradesh, India, reveals complete absence of E1:A226V mutation

2016 ◽  
Vol 60 (01) ◽  
pp. 114-117 ◽  
Author(s):  
C. V. M. NARESH KUMAR ◽  
Y. SIVAPRASAD ◽  
D. V. R. SAI GOPAL
Keyword(s):  
Genetic Diversity ◽  
Andhra Pradesh ◽  
Chikungunya Virus ◽  
A226v Mutation

scholarly journals Complete Coding Sequence of a Chikungunya Virus Strain Imported into Slovenia from Thailand in Late 2018

2019 ◽  
Vol 8 (37) ◽  
Author(s):  
Samo Zakotnik ◽  
Misa Korva ◽  
Nataša Knap ◽  
Barbara Robnik ◽  
Nina Gorišek Miksić ◽  
...  
Keyword(s):  
Cell Culture ◽  
Phylogenetic Analysis ◽  
Envelope Protein ◽  
Viral Genome ◽  
Chikungunya Virus ◽  
Whole Genome ◽  
Reverse Transcription Pcr ◽  
The Indian Ocean ◽  
Complete Viral Genome ◽  
A226v Mutation

A case of chikungunya virus infection was imported from Thailand into Slovenia in late 2018. The infection was diagnosed using real-time reverse transcription-PCR, the virus was isolated in cell culture, and the whole genome was sequenced. Phylogenetic analysis of the nearly complete viral genome indicated that the virus belongs to the Indian Ocean lineage but does not possess the A226V mutation in the envelope protein E1.

scholarly journals Comprehensive Genome Scale Phylogenetic Study Provides New Insights on the Global Expansion of Chikungunya Virus

2016 ◽  
Vol 90 (23) ◽  
pp. 10600-10611 ◽  
Author(s):  
Rubing Chen ◽  
Vinita Puri ◽  
Nadia Fedorova ◽  
David Lin ◽  
Kumar L. Hari ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Indian Ocean ◽  
Chikungunya Virus ◽  
Pacific Islands ◽  
Indian Subcontinent ◽  
Global Distribution ◽  
Phylogenetic Study ◽  
Content Type ◽  
Factors Associated ◽  
Asian Lineage

ABSTRACT Since the India and Indian Ocean outbreaks of 2005 and 2006, the global distribution of chikungunya virus (CHIKV) and the locations of epidemics have dramatically shifted. First, the Indian Ocean lineage (IOL) caused sustained epidemics in India and has radiated to many other countries. Second, the Asian lineage has caused frequent outbreaks in the Pacific islands and in 2013 was introduced into the Caribbean, followed by rapid spread to nearly all of the neotropics. Further, CHIKV epidemics, as well as exported cases, have been reported in central Africa after a long period of perceived silence. To understand these changes and to anticipate the future of the virus, the exact distribution, genetic diversity, transmission routes, and future epidemic potential of CHIKV require further assessment. To do so, we conducted the most comprehensive phylogenetic analysis to date, examined CHIKV evolution and transmission, and explored distinct genetic factors associated with the emergence of the East/Central/South African (ECSA) lineage, the IOL, and the Asian lineage. Our results reveal contrasting evolutionary patterns among the lineages, with growing genetic diversities observed in each, and suggest that CHIKV will continue to be a major public health threat with the potential for further emergence and spread. IMPORTANCE Chikungunya fever is a reemerging infectious disease that is transmitted by Aedes mosquitoes and causes severe health and economic burdens in affected populations. Since the unprecedented Indian Ocean and Indian subcontinent outbreaks of 2005 and 2006, CHIKV has further expanded its geographic range, including to the Americas in 2013. Its evolution and transmission during and following these epidemics, as well as the recent evolution and spread of other lineages, require optimal assessment. Using newly obtained genome sequences, we provide a comprehensive update of the global distribution of CHIKV genetic diversity and analyze factors associated with recent outbreaks. These results provide a solid foundation for future evolutionary studies of CHIKV that can elucidate emergence mechanisms and also may help to predict future epidemics.

scholarly journals Surveillance of chikungunya virus in Andhra Pradesh, Southern India

2010 ◽  
Vol 3 (11) ◽  
pp. 860-865 ◽  
Author(s):  
CVM Naresh Kumar ◽  
P Sangamithra ◽  
M Rajasekhar ◽  
DVR Saigopal
Keyword(s):  
Andhra Pradesh ◽  
Chikungunya Virus ◽  
Southern India

scholarly journals Chikungunya virus with E1-A226V mutation causing two outbreaks in 2010, Guangdong, China

2013 ◽  
Vol 10 (1) ◽  
pp. 174 ◽  
Author(s):  
De Wu ◽  
Yonghui Zhang ◽  
Qiong ZhouHui ◽  
Jing Kou ◽  
Wenjia Liang ◽  
...  
Keyword(s):  
Chikungunya Virus ◽  
A226v Mutation

scholarly journals The extent of genetic diversity among popular rice cultivars of Andhra pradesh and Telangana using microsatellite markers

2016 ◽  
Vol 7 (4) ◽  
pp. 1089
Author(s):  
CH.V. Durga Rani ◽  
S Vanisri ◽  
Jamaloddin Mohammed ◽  
Swathi Gattu ◽  
Ramprasad Eruvuri ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Microsatellite Markers ◽  
Andhra Pradesh ◽  
Rice Cultivars

scholarly journals Genetic Diversity in Roselle (Hibiscus sabdariffa L.) for Fiber Yield Traits in North Coastal Zone of Andhra Pradesh, India

2017 ◽  
Vol 6 (8) ◽  
pp. 2335-2341
Author(s):  
N. Hari Satyanarayana ◽  
V. Visalakshmi ◽  
J. Jagannadham ◽  
K. Madhu Kumar ◽  
P. Amarajyothi ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Coastal Zone ◽  
Andhra Pradesh ◽  
Yield Traits ◽  
Hibiscus Sabdariffa ◽  
Fiber Yield

Genetic diversity and variability for protein and micro nutrients in advance breeding lines and chickpea varieties grown in Andhra Pradesh

2018 ◽  
Author(s):  
V. Jayalakshmi ◽  
A. Trivikrama Reddy ◽  
K. V. Nagamadhuri
Keyword(s):  
Genetic Diversity ◽  
Andhra Pradesh ◽  
Nutritional Value ◽  
Nutrient Content ◽  
Genetic Advance ◽  
Breeding Lines ◽  
Breeding Programmes ◽  
High Heritability ◽  
Diversity Studies ◽  
Chickpea Cultivars

An investigation was taken up to study the nutritional value, extent of genetic variability and genetic diversity in advance breeding lines and chickpea varieties grown in Andhra Pradesh, India. Protein and micronutrient content (iron, zinc, copper and manganese) varied significantly among 54 genotypes. Protein content ranged from 9.5% to 24.9% while micro nutrients varied from 2.6 mg/100 g to 14.6 mg/100 g for iron, 3.5 mg/100 g to 7.7 mg/100 g for zinc, 0.5 mg/100 g to 3.2 mg/100 g for copper and 1.6 mg/100 g to 3.4 mg/100 g for manganese. Moderate to high genotypic variability for protein and micro nutrient content with high heritability and genetic advance indicated the scope for enhancement of traits through selection. Genetic diversity studies revealed five different clusters and that high protein lines are grouped in cluster I and lines with higher concentration of micro nutrients are grouped in clusters IV and V. Systematic hybridization between promising lines for protein and micronutrients chosen from these clusters is suggested to study their combining ability and subsequent use in breeding programmes intended to breed for superior chickpea cultivars.

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