Adherence to therapy in schizophrenia

2012 ◽  
Author(s):  
Alex Hofer ◽  
W. Wolfgang Fleischhacker ◽  
Suzanne M. Hardeman ◽  
Melissa H. Kannaday ◽  
Meera Narasimhan ◽  
...  
Keyword(s):  
Adherence To Therapy

Optimizing adherence to therapy in patients with non-specific back pain

2016 ◽  
Vol 18 (9) ◽  
pp. 147-150 ◽  
Author(s):  
M.N. Dadasheva ◽  
◽  
N.Yu. Taranenko ◽  
Keyword(s):  
Back Pain ◽  
Adherence To Therapy

scholarly journals AB0474 THE USE OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS) IN WOMEN WITH ANKYLOSING SPONDYLITIS (AS) DURING PREGNANCY

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1264.2-1265
Author(s):  
O. Krichevskaya ◽  
T. Dubinina ◽  
E. Ilinykh ◽  
S. Glukhova ◽  
A. Demina
Keyword(s):  
New York ◽  
Back Pain ◽  
Nsaid Therapy ◽  
International Studies ◽  
Average Daily Dose ◽  
Time Data ◽  
The Third ◽  
Increased Risk ◽  
Daily Dose ◽  
Adherence To Therapy

Background:NSAIDs remain the first-line drugs in treatment of AS. During pregnancy, COX-2 non-selective NSAIDs are allowed for intake up to 32 weeks, but the question of the dose-dependent effect of NSAIDs on fetal organogenesis in the 1st trimester and on fetal kidney function and the increased risk of bleeding in childbirth when taken in the second half of pregnancy continues to be discussed. At the same time, data on the effectiveness of NSAIDs, including their low and medium doses, during pregnancy are extremely small.Objectives:to describe the frequency of using NSAIDs during pregnancy, to determine relationship between the dose of NSAIDs, adherence to therapy with the activity of AS.Methods:50 pregnancies were followed in 49 pregnant women with confirmed AS (modified New York criteria, 1984). The average age of the pts was 31.6 ± 4.9 years, the duration of the disease was 134.4 ± 85.8 months. The visits were conducted at 10-11, 20-21, and 31-32 weeks of pregnancy. The BASDAI in the month of conception and in the trimesters (trim.) of pregnancy was: 1,4[0,6; 3,3]; 2,3[1,2; 4,4]; 2,8[1,4; 4,2] and 2,2[1,6; 4,0], respectively. The level of nocturnal back pain according to the NRS in the first, second and third trim. was: 3.2±2.0; 5.4±2.5 and 5.2±2.6, respectively. The drug of choice was ibuprofen at a maximum daily dose of 1200 mg, its withdrawal - no later than 32 weeks of pregnancy.Adherence to NSAID therapy was defined as the ratio of the actual dose taken to the prescribed dose; an indicator of less than 80% was regarded as non-adherence to therapy. The total dose of NSAIDs was determined by the NSAID intake index (M. Dougados, 2001). The” actual daily dose” of ibuprofen was the sum of the doses of ibuprofen taken, divided by the number of actual days of taking the drug. The “average daily dose” was defined as the sum of the ibuprofen doses taken, divided by the number of days in the trimester.Results:At the time of conception and in the first, second and third trim. of pregnancy, NSAIDs were taken 23 (46%), 20 (40%), 30 (60%) and 21 (43.8%) women, respectively. The NSAID intake index, the actual and average daily dose of ibuprofen are shown in the Table 1.month of conceptiontrim. 1trim. 2trim. 3the actual daily dose, mg-700[425; 800]800[400; 1000]750[400; 1200]the average daily dose, mg-158[87,9; 307,7]355,1[138,5; 685,7]580[320; 1200]NSAIDs intake index28,6 [16,7; 50]5,8 [2,9; 11,8]15,5 [4,7; 30,9]24,4 [9,5; 50]The index of NSAID intake in the first trim. was lower than before pregnancy and in the second half of gestation (p<0.05 compared to the month of conception, II and III trim.). The average daily dose of ibuprofen was also lower in the first trim. than in the second and third trim. (p<0.05), while the actual daily dose in the second trim. was higher than in the first and third trim. (p<0.05 in all cases).There was no correlation between BASDAI AS activity, the level of nocturnal pain and the ibuprofen intake index, likewise the fact of NSAID withdrawal throughout pregnancy. In addition, there were no differences in BASDAI levels and back pain in women with a subjective need for NSAIDs, who did and did’t take ibuprofen.50% of women were committed to NSAID therapy in the first trim., 43.5% in the second trim., and 67.4% in the third trim. In pts with non-adherence to NSAID therapy, the BASDAI level was higher than in those who followed the recommendations of the rheumatologist throughout pregnancy: in the first trim. – 3.8[3.4; 4.7] and 1.7[0.8; 2.2]; in the second trim. - 3[2.3; 4.6] and 1.4[0.8; 2.7]; in the third trim. - 3.1[2.1; 4.0] and 1.7[1.1; 4.0], p<0.05 in all cases. However, women with adherence > 80% were initially less active and NSAIDs were prescribed “on demand”, which increased their compliance.Conclusion:intake of ibuprofen in low doses does not affect the activity of AS. Due to the ongoing discussion about the effect of NSAIDs on neonatal outcomes, further international studies are required for development an optimal treatment regimen during pregnancy with a possible extension of the indications for the appointment of TNF inhibitors (BASDAI<4).Disclosure of Interests:None declared.

scholarly journals Adherence to Therapy, Physical and Mental Quality of Life in Patients with Multiple Sclerosis

2021 ◽  
Vol 11 (7) ◽  
pp. 672
Author(s):  
Alessandra Buja ◽  
Guendalina Graffigna ◽  
Simona F. Mafrici ◽  
Tatjana Baldovin ◽  
Carlo Pinato ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Behavioral Interventions ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Health Index ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Adherence To Therapy

Ensuring multiple sclerosis (MS) patients’ adherence to therapy is often challenging, but it is crucial to their survival and health-related quality of life (HRQoL). The aim of the present study was to outline connections between adherence, physical and mental HRQoL, levels of psychological readiness to engage in a treatment, levels of social support, anthropometric, socio-demographic and clinical factors in patients suffering from MS. This cross-sectional study involved a sample of 237 Italian MS patients. A survey was conducted with a structured self-administered online questionnaire using validated measures of quality of life, adherence to therapy and anthropometric, socio-demographic, psychological and clinical variables. A path analysis was used to test the overall structure of the associations between the variables. The pathway indicates a positive association between mental health index and a stronger degree of engagement and being or having been in a long-term relationship. Physical health index was positively associated with age, having an occupation, and having a specific form of MS. Having had relapses in the previous year raised the odds of better adherence to therapy, while an increase in Body Mass Index (BMI) reduced them. Our findings could help in the management of MS patients, promoting behavioral interventions that take the psychological and socio-demographic peculiarities of each patient into account with a view to improving their adherence to therapy.

A Wearable AR-based BCI for Robot Control in ADHD Treatment: Preliminary Evaluation of Adherence to Therapy

2021 ◽  
Author(s):  
Pasquale Arpaia ◽  
Sabatina Criscuolo ◽  
Egidio De Benedetto ◽  
Nicola Donato ◽  
Luigi Duraccio
Keyword(s):  
Robot Control ◽  
Preliminary Evaluation ◽  
Adhd Treatment ◽  
Adherence To Therapy

scholarly journals Adherence to therapy for Barrett’s esophagus‐associated neoplasia

2016 ◽  
Vol 4 (1) ◽  
pp. 42-48 ◽  
Author(s):  
Lisa Cassani ◽  
James C Slaughter ◽  
Patrick Yachimski
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Adherence To Therapy

scholarly journals Adherence To Therapy Among Diabetes Patients In A Niger Delta Referral Center

2013 ◽  
Vol 16 (3) ◽  
pp. A167-A168
Author(s):  
I.A. Suleiman ◽  
W.O. Siasia ◽  
I.E. Egbesu
Keyword(s):  
Niger Delta ◽  
Referral Center ◽  
Adherence To Therapy ◽  
Diabetes Patients

scholarly journals The Effect Of Counseling On The Adherence Of Therapeutic Hypertension Patients

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
Gita Sekar Prihanti ◽  
Novi Puspita Sari ◽  
Nur Indah Septiani ◽  
Laura Putri Risty L. Tobing ◽  
Annisa Rahayu Adrian ◽  
...  
Keyword(s):  
Family Support ◽  
Statistical Tests ◽  
Adherence Rate ◽  
Test Results ◽  
A Value ◽  
Significant Difference ◽  
Post Test ◽  
Lifestyle Education ◽  
Nonparametric Statistical ◽  
Adherence To Therapy

Failure of therapy is a result of bad adherence  medication. Non-adherence to therapy is a major factor that is suspected to result in uncontrolled blood pressure in hypertensive patients resulting in more serious complications. Therefore it is important to increase the adherence rate of treatment in patients with hypertension in the treatment process. For this reason, the need for interventions to improve  adherence  with several aspects that can be changed. This study uses One Group Pretest-Posttest Design using 100 samples. Data derived from questionnaires containing 25 items of adherence to therapy, 5 items of knowledge, 4 items of trust, 3 items of motivation, 10 items of family support with nonparametric statistical tests used were Mc Nemar test. Mc Nemar test results indicate that there is a significant difference between adherence at the pre-test and at the post-test after counseling with a significance value (p = 0,000). The results also showed that there was a difference in knowledge with a significance value (p = 0.001), motivation with a value (p = 0.031) and family support with a value (p = 0,000). The education with counseling about knowledge, trust, motivation and family support is effective in increasing compliance. There are other changeable factors such as lifestyle education, patient doctor relationships, and the use of smartphone applications for self-reported therapy can improve adherence in patients thereby minimizing therapy failure. Other educational methods that can be used besides counseling are counseling and dissemination of social media information.

scholarly journals Is it possible to identify compliance and adherence to therapy? Experts opinion

2020 ◽  
Vol 23 (3) ◽  
pp. 174-181
Author(s):  
Tatiana V. Sokolova ◽  
M. S. Davidenko ◽  
Alеxandr P. Malyarchuk
Keyword(s):  
Patient Compliance ◽  
Medical Literature ◽  
Disease Patient ◽  
Adherence To Therapy

Today, the terms compliance and adherence are often used in the medical literature. The problem of patient compliance/adherence to therapy is the basis of the physicianpatient relationship complex. The study of this complex is used by specialists with various profiles to assess the effectiveness of therapy. This publication has studied the opinion of specialists when answering the following question: Is it possible to identify compliance and adherence to therapy? The factors determining the compliance/adherence of patients to treatment regardless of nosological forms of the disease are systematized. A total of four groups of factors of nonadherence to therapy associated with the disease, patient, doctor, and treatment were identified in this study.

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