Neuropathic pain and diabetes: focus on mechanisms and potential therapeutic strategies

Author(s):  
Giuseppe Lauria
Pain ◽  
2020 ◽  
Vol 161 (Supplement 1) ◽  
pp. S14-S26 ◽  
Author(s):  
Srinivasa N. Raja ◽  
Matthias Ringkamp ◽  
Yun Guan ◽  
James N. Campbell

2018 ◽  
Vol 10 ◽  
pp. 117957351877170 ◽  
Author(s):  
Todd D Levine

Small fiber neuropathy (SFN) has a poorly understood pathology, but patients would benefit from determination of clinical phenotypes that allows for better diagnosis and treatment planning. I propose that patients should be classified dependent on whether there is sodium channel dysfunction, classic neurologic symptoms only, widespread neuropathic pain, or autonomic symptoms. Patients with SFN can then be considered in light of their clinical phenotype, allowing for focus on subsets of patients who might have diagnosable conditions or be more prone to responding to a particular type of therapy that may not be efficacious in the broader patient population with SFN. There are several therapies currently available that can address the symptoms of SFN; however, to develop novel therapeutic strategies, it will be imperative to classify patients to understand and target the underlying pathology.


2005 ◽  
Vol 38 (10) ◽  
pp. 15
Author(s):  
Sherry Boschert
Keyword(s):  

2009 ◽  
Vol 42 (18) ◽  
pp. 50
Author(s):  
KATE JOHNSON
Keyword(s):  

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