scholarly journals Health-Related Quality of Life Changes in Prostate Cancer Patients after Radical Prostatectomy: A Longitudinal Cohort Study

2019 ◽  
Vol 51 (2) ◽  
pp. 556-567 ◽  
Author(s):  
Dong Wook Shin ◽  
Sang Hyub Lee ◽  
Tae-Hwan Kim ◽  
Seok Joong Yun ◽  
Jong Kil Nam ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Cohort Study ◽  
Radical Prostatectomy ◽  
Cancer Patients ◽  
Life Changes ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Health Related Quality of Life and Patient Satisfaction in Prostate Cancer Patients Treated Through Radical Prostatectomy

2014 ◽  
Vol 17 (7) ◽  
pp. A647
Author(s):  
H. Solano-Moreno ◽  
O.R. Ramirez-Muñoz ◽  
L.M.A. Balderas-Peña ◽  
E.A. Flores-Larios ◽  
R.E. Ramírez-Conchas ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Patient Satisfaction ◽  
Radical Prostatectomy ◽  
Cancer Patients ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

PD18-03 LONG-TERM HEALTH RELATED QUALITY OF LIFE IN PROSTATE CANCER PATIENTS REQUIRING RADIOTHERAPY AFTER RADICAL PROSTATECTOMY

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Louis Aliperti ◽  
Dattatraya Patil ◽  
Akanksha Mehta ◽  
Christopher Filson ◽  
Catrina Crociani ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Cancer Patients ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Health-Related Quality of Life following Cytoreductive Radical Prostatectomy in Patients with de-novo Oligometastatic Prostate Cancer

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5636
Author(s):  
Michael Chaloupka ◽  
Lina Stoermer ◽  
Maria Apfelbeck ◽  
Alexander Buchner ◽  
Vera Wenter ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
De Novo ◽  
Health Related Quality ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related

(1) Background: local treatment of the primary tumor has become a valid therapeutic option in de-novo oligo-metastatic prostate cancer (PC). However, evidence regarding radical prostatectomy (RP) in this setting is still subpar, and the effect of cytoreductive RP on postoperative health-related quality of life (HRQOL) is still unclear. (2) Methods: for the current study, patients with de-novo oligo-metastatic PC (cM1-oligo), defined as ≤5 bone lesions in the preoperative staging, were included, and matched cohorts using the variables age, body-mass index (BMI), and pT-stage were generated. Patient-reported outcome measures (PROMS) were assessed pre- and postoperatively using the validated EORTC-QLQ-C30, IIEF-5, and ICIQ-SF questionnaires. The primary endpoint for univariate and multivariable analysis was good general HRQOL defined by previously validated cut-off values. (3) Results: in total, 1268 patients (n = 84 (7%) cM1-oligo) underwent RP between 2012 and 2020 at one tertiary care center. A matched cohort of 411 patients (n = 79 with oligo-metastatic bone disease (cM1-oligo) and n = 332 patients without clinical indication of metastatic disease (cM0)) was created. The median follow-up was 25mo. There was no significant difference in good general HRQOL rates between cM1-oligo-patients and cM0-patients before RP (45.6% vs. 55.2%, p = 0.186), and at time of follow-up (44% vs. 56%, p = 0.811). Global health status (GHS) worsened significantly in cM0-patients compared to baseline (−5, p = 0.001), whereas GHS did not change significantly in cM1-oligo-patients (+3.2, p = 0.381). In multivariate analysis stratified for good erectile function (IIEF5 > 18; OR 5.722, 95% CI 1.89–17.36, p = 0.002) and continence recovery (OR 1.671, 95% CI 1.03–2.70, p = 0.036), cM1-oligo was not an independent predictive feature for general HRQOL (OR 0.821, 95% CI 0.44–1.53, p = 0.536). (4) Conclusions: in this large contemporary retrospective analysis, we observed no significant difference in HRQOL in patients with the oligometastatic bone disease after cytoreductive radical prostatectomy, when compared to patients with localized disease at time of surgery.

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