scholarly journals Phase II Study of Induction Chemotherapy with Docetaxel, Capecitabine, and Cisplatin Plus Bevacizumab for Initially Unresectable Gastric Cancer with Invasion of Adjacent Organs or Paraaortic Lymph Node Metastasis

2018 ◽  
Vol 50 (2) ◽  
pp. 518-529 ◽  
Author(s):  
Jwa Hoon Kim ◽  
Sook Ryun Park ◽  
Min-Hee Ryu ◽  
Baek-Yeol Ryoo ◽  
Kyu-pyo Kim ◽  
...  
1993 ◽  
Vol 26 (12) ◽  
pp. 2822-2826
Author(s):  
Kazuomi Iwasaki ◽  
Takuo Shinozaki ◽  
Satoshi Yamaguchi ◽  
Takafumi Urakawa ◽  
Kazuya Okada ◽  
...  

2006 ◽  
Vol 41 (4) ◽  
pp. 391-392 ◽  
Author(s):  
Takahiro Uenishi ◽  
Osamu Yamazaki ◽  
Katsuhiko Horii ◽  
Takatsugu Yamamoto ◽  
Shoji Kubo

Author(s):  
Hui-Hua Chen ◽  
Wan-Hua Ting ◽  
Hsu-Dong Sun ◽  
Ming-Chow Wei ◽  
Ho-Hsiung Lin ◽  
...  

Background: to elucidate the predictors of progression-free survival (PFS) and overall survival (OS) in high-risk endometrial cancer patients. Methods: the medical records of all consecutivewomen with high-risk endometrial cancer were reviewed. Results: among 92 high-risk endometrial cancer patients, 30 women experienced recurrence, and 21 women died. The 5-year PFS and OS probabilities were 65.3% and 75.9%, respectively. Multivariable Cox regression revealed that body mass index (hazard ratio (HR) = 1.11), paraaortic lymph node metastasis (HR = 11.11), lymphovascular space invasion (HR = 5.61), and sandwich chemoradiotherapy (HR = 0.15) were independently predictors of PFS. Body mass index (HR = 1.31), paraaortic lymph node metastasis (HR = 32.74), non-endometrioid cell type (HR = 11.31), and sandwich chemoradiotherapy (HR = 0.07) were independently predictors of OS. Among 51 women who underwent sandwich (n = 35) or concurrent (n = 16) chemoradiotherapy, the use of sandwich chemoradiotherapy were associated with better PFS (adjusted HR = 0.26, 95% CI = 0.08–0.87, p = 0.03) and OS (adjusted HR = 0.11, 95% CI = 0.02–0.71, p = 0.02) compared with concurrent chemoradiotherapy. Conclusion: compared with concurrent chemoradiotherapy, sandwich chemoradiotherapy was associated with better PFS and OS in high-risk endometrial cancer patients. In addition, high body mass index, paraaortic lymph node metastasis, and non-endometrioid cell type were also predictors of poor OS in high-risk endometrial cancer patients.


Sign in / Sign up

Export Citation Format

Share Document