scholarly journals Molecular epidemiology of Aleutian mink disease virus causing outbreaks in mink farms from Southwestern Europe: a retrospective study from 2012 to 2019

2020 ◽  
Vol 21 (4) ◽  
Author(s):  
Alberto Prieto ◽  
Ricardo Fernández-Antonio ◽  
Gonzalo López-Lorenzo ◽  
José Manuel Díaz-Cao ◽  
Cynthia López-Novo ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Molecular Epidemiology ◽  
Disease Virus ◽  
Aleutian Mink Disease Virus

scholarly journals Molecular epidemiology of Aleutian mink disease virus from fecal swab of mink in northeast China

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Mingwei Tong ◽  
Na Sun ◽  
Zhigang Cao ◽  
Yuening Cheng ◽  
Miao Zhang ◽  
...  
Keyword(s):  
Molecular Epidemiology ◽  
Disease Virus ◽  
Northeast China ◽  
Aleutian Mink Disease Virus

Molecular epidemiology of Aleutian mink disease virus in Finland

2009 ◽  
Vol 133 (3) ◽  
pp. 229-238 ◽  
Author(s):  
Anna Knuuttila ◽  
Nathalie Uzcátegui ◽  
Johanna Kankkonen ◽  
Olli Vapalahti ◽  
Paula Kinnunen
Keyword(s):  
Molecular Epidemiology ◽  
Disease Virus ◽  
Aleutian Mink Disease Virus

Molecular epidemiology of Aleutian mink disease virus (AMDV) in Estonia, and a global phylogeny of AMDV

2015 ◽  
Vol 199 ◽  
pp. 56-61 ◽  
Author(s):  
Aivi Leimann ◽  
Anna Knuuttila ◽  
Tiit Maran ◽  
Olli Vapalahti ◽  
Urmas Saarma
Keyword(s):  
Molecular Epidemiology ◽  
Disease Virus ◽  
Aleutian Mink Disease Virus

Molecular epidemiology of Aleutian mink disease virus in China

2014 ◽  
Vol 184 ◽  
pp. 14-19 ◽  
Author(s):  
Zhenjun Wang ◽  
Wei Wu ◽  
Bo Hu ◽  
Hailing Zhang ◽  
Xue Bai ◽  
...  
Keyword(s):  
Molecular Epidemiology ◽  
Disease Virus ◽  
Aleutian Mink Disease Virus

scholarly journals Aptamer-targeting of Aleutian mink disease virus (AMDV) can be an effective strategy to inhibit virus replication

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Taofeng Lu ◽  
Hui Zhang ◽  
Jie Zhou ◽  
Qin Ma ◽  
Wenzhuo Yan ◽  
...  
Keyword(s):  
Disease Virus ◽  
Magnetic Beads ◽  
Inhibitory Effect ◽  
Three Dimensions ◽  
Economic Losses ◽  
Effective Vaccine ◽  
Stem Loop ◽  
Aleutian Mink Disease Virus ◽  
Random Library

AbstractAleutian mink disease (AMD), which is caused by Aleutian mink disease virus (AMDV), is an important contagious disease for which no effective vaccine is yet available. AMD causes major economic losses for mink farmers globally and threatens some carnivores such as skunks, genets, foxes and raccoons. Aptamers have exciting potential for the diagnosis and/or treatment of infectious viral diseases, including AMD. Using a magnetic beads-based systemic evolution of ligands by exponential enrichment (SELEX) approach, we have developed aptamers with activity against AMDV after 10 rounds of selection. After incubation with the ADVa012 aptamer (4 μM) for 48 h, the concentration of AMDV in the supernatant of infected cells was 47% lower than in the supernatant of untreated cells, whereas a random library of aptamers has no effect. The half-life of ADVa012 was ~ 32 h, which is significantly longer than that of other aptamers. Sequences and three dimensions structural modeling of selected aptamers indicated that they fold into similar stem-loop structures, which may be a preferred structure for binding to the target protein. The ADVa012 aptamer was shown to have an effective and long-lasting inhibitory effect on viral production in vitro.

scholarly journals Evolution and molecular epidemiology of foot-and-mouth disease virus in China

2011 ◽  
Vol 56 (21) ◽  
pp. 2191-2201 ◽  
Author(s):  
XingWen Bai ◽  
PingHua Li ◽  
HuiFang Bao ◽  
ZaiXin Liu ◽  
Dong Li ◽  
...  
Keyword(s):  
Molecular Epidemiology ◽  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Mouth Disease Virus ◽  
Foot And Mouth
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