scholarly journals The degree of major histocompatibility complex matching between purebred Maltese and mongrel dogs using microsatellite markers

2019 ◽  
Vol 20 (2) ◽  
Author(s):  
Ho-Hyun Kwak ◽  
Heung-Myong Woo ◽  
Kyung-Mee Park
2014 ◽  
Vol 19 (1) ◽  
Author(s):  
Cesar Daniel Petroli ◽  
Samuel Rezende Paiva ◽  
Tiago Do Prado Paim ◽  
Concepta Margaret McManus

O objetivo deste estudo foi de associar alelos de 13 loci de microssatélites no cromossomo 20 de ovinos (Major Histocompatibility Complex - MHC) com características de desempenho e carcaça bem como resistência à parasitas  gastrointestinais em 138 ovinos Santa Inês e seus cruzamentos com Bergamasca, Texel e Ile de France. Os seguintes loci foram selecionados: BM1818, OarCP73, OarHH56, DYA, OLADRB, CP101, OMHC1, DQA2, DQA1, TFAP2A, DQBA27, Bf94_1, e INRA132.  Dados foram analisados em Cervus e SAS ® para determinar níveis de heterozygosidade e associações de marcadores com peso, carcaça e ovos por grama de fezes (OPG).  Os marcadores mostraram alta variabilidade genética entre indivíduos.  Para características de carcaça oito associações significativas (p<0.05) foram observadas, bem como associação positiva entre OPG e dois marcadores da MHC ovina.


2017 ◽  
Vol 8 (s1) ◽  
pp. s19-s21
Author(s):  
L. Haikukutu ◽  
T. O. Itenge ◽  
L. Bosman ◽  
C. Visser ◽  
E. van Marle-Köster

The major histocompatibility complex region has been implicated in explaining some of the variation observed in adaptability and tick susceptibility of cattle. The bovine leukocyte antigen region of 192 cattle representing indigenous, composite and exotic breeds used in commercial beef production in Namibia and South Africa was investigated using four microsatellite markers. Ticks counted under the tail were taken as an indicator of tick susceptibility. Tick scores of all but one population was low (11 to 20 ticks), with only the South African Bonsmara population having an average score of 31 to 40 ticks per animal. The observed variation based on four microsatellite markers ranged from 5.5 alleles in Namibian Afrikaner to 7.7 alleles in South African Nguni and Bonsmara cattle. Unbiased heterozygosity values ranged from 0.66 (Namibian Afrikaner) to 0.76 (South African Bonsmara). Structure analyses grouped the five populations into three indistinct clusters with limited genetic variation between the populations.


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