scholarly journals A Salmonella Typhi ghost induced by the E gene of phage φX174 stimulates dendritic cells and efficiently activates the adaptive immune response

2018 ◽  
Vol 19 (4) ◽  
pp. 536 ◽  
Author(s):  
Gayeon Won ◽  
Seong Kug Eo ◽  
Sang-Youel Park ◽  
Jin Hur ◽  
John Hwa Lee
2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Luciana D’Apice ◽  
Valerio Costa ◽  
Rossella Sartorius ◽  
Maria Trovato ◽  
Marianna Aprile ◽  
...  

The filamentous bacteriophage fd, codisplaying antigenic determinants and a single chain antibody fragment directed against the dendritic cell receptor DEC-205, is a promising vaccine candidate for its safety and its ability to elicit innate and adaptive immune response in absence of adjuvants. By using a system vaccinology approach based on RNA-Sequencing (RNA-Seq) analysis, we describe a relevant gene modulation in dendritic cells pulsed with anti-DEC-205 bacteriophages fd. RNA-Seq data analysis indicates that the bacteriophage fd virions are sensed as a pathogen by dendritic cells; they activate the danger receptors that trigger an innate immune response and thus confer a strong adjuvanticity that is needed to obtain a long-lasting adaptive immune response.


2018 ◽  
Vol 14 (11) ◽  
pp. e1007437 ◽  
Author(s):  
Mayuri Gogoi ◽  
Kasturi Chandra ◽  
Mohsen Sarikhani ◽  
Ramya Ramani ◽  
Nagalingam Ravi Sundaresan ◽  
...  

2009 ◽  
Vol 182 (5) ◽  
pp. 2888-2897 ◽  
Author(s):  
Emanuele Fanales-Belasio ◽  
Sonia Moretti ◽  
Valeria Fiorelli ◽  
Antonella Tripiciano ◽  
Maria R. Pavone Cossut ◽  
...  

2007 ◽  
Vol 46 ◽  
pp. S174
Author(s):  
I. Pachiadakis ◽  
S. Choksi ◽  
H. Cooksley ◽  
C. Sarrazzin ◽  
S. Zeuzem ◽  
...  

2008 ◽  
Vol 38 (4) ◽  
pp. 1024-1032 ◽  
Author(s):  
Undine Lippert ◽  
Karolin Zachmann ◽  
David M. Ferrari ◽  
Herbert Schwarz ◽  
Edgar Brunner ◽  
...  

Vaccine ◽  
2009 ◽  
Vol 27 (41) ◽  
pp. 5581-5588 ◽  
Author(s):  
Lilian Lacerda Bueno ◽  
Cristiane Guimarães Morais ◽  
Irene da Silva Soares ◽  
Leoneide Erica Maduro Bouillet ◽  
Oscar Bruna-Romero ◽  
...  

2020 ◽  
Vol 16 (2) ◽  
pp. e1008345
Author(s):  
Mayuri Gogoi ◽  
Kasturi Chandra ◽  
Mohsen Sarikhani ◽  
Ramya Ramani ◽  
Nagalingam Ravi Sundaresan ◽  
...  

2008 ◽  
Vol 38 (6) ◽  
pp. 1767-1767
Author(s):  
Undine Lippert ◽  
Karolin Zachmann ◽  
David M. Ferrari ◽  
Herbert Schwarz ◽  
Edgar Brunner ◽  
...  

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