scholarly journals Quantitative measurement of influenza virus replication using consecutive bronchoalveolar lavage in the lower respiratory tract of a ferret model

2014 ◽  
Vol 15 (3) ◽  
pp. 439 ◽  
Author(s):  
Dong-Hun Lee ◽  
Jong-In Kim ◽  
Jae-Won Lee ◽  
Wook-Hun Chung ◽  
Jae-Keun Park ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Respiratory Tract ◽  
Bronchoalveolar Lavage ◽  
Virus Replication ◽  
Lower Respiratory Tract ◽  
Quantitative Measurement ◽  
Influenza Virus Replication

scholarly journals Interferon-Induced Expression of MxA in the Respiratory Tract of Rhesus Macaques Is Suppressed by Influenza Virus Replication

2008 ◽  
Vol 180 (4) ◽  
pp. 2385-2395 ◽  
Author(s):  
Timothy D. Carroll ◽  
Shannon R. Matzinger ◽  
Meritxell Genescà ◽  
Linda Fritts ◽  
Roxana Colòn ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Respiratory Tract ◽  
Virus Replication ◽  
Rhesus Macaques ◽  
Induced Expression ◽  
Influenza Virus Replication

scholarly journals A Defective Interfering Influenza RNA Inhibits Infectious Influenza Virus Replication in Human Respiratory Tract Cells: A Potential New Human Antiviral

Viruses ◽  
2016 ◽  
Vol 8 (8) ◽  
pp. 237 ◽  
Author(s):  
Claire Smith ◽  
Paul Scott ◽  
Christopher O’Callaghan ◽  
Andrew Easton ◽  
Nigel Dimmock
Keyword(s):  
Influenza Virus ◽  
Respiratory Tract ◽  
Virus Replication ◽  
Human Respiratory Tract ◽  
Influenza Virus Replication

scholarly journals In SilicoApproach towards Designing Virtual Oligopeptides for HRSV

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Ruchi Jain ◽  
Shanmughavel Piramanayagam
Keyword(s):  
Respiratory Syncytial Virus ◽  
Respiratory Tract ◽  
Virus Replication ◽  
Lower Respiratory Tract ◽  
Specific Interaction ◽  
Infection Process ◽  
Rational Choices ◽  
Respiratory Tract Illness ◽  
Syncytial Virus ◽  
Infants And Young Children

HRSV (human respiratory syncytial virus) is a serious cause of lower respiratory tract illness in infants and young children. Designing inhibitors from the proteins involved in virus replication and infection process provides target for new therapeutic treatments. In the present study,in silicodocking was performed using motavizumab as a template to design motavizumab derived oligopeptides for developing novel anti-HRSV agents. Additional simulations were conducted to study the conformational propensities of the oligopeptides and confirmed the hypothesis that the designed oligopeptide is highly flexible and capable of assuming stable confirmation. Our study demonstrated the best specific interaction of GEKKLVEAPKS oligopeptide for glycoprotein strain A among various screened oligopeptides. Encouraged by the results, we expect that the proposed scheme will provide rational choices for antibody reengineering which is useful for systematically identifying the possible ways to improve efficacy of existing antibody drugs.

scholarly journals Targeting Cell Division Cycle 25 Homolog B To Regulate Influenza Virus Replication

2013 ◽  
Vol 87 (24) ◽  
pp. 13775-13784 ◽  
Author(s):  
O. Perwitasari ◽  
A. C. Torrecilhas ◽  
X. Yan ◽  
S. Johnson ◽  
C. White ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Cell Division ◽  
Virus Replication ◽  
Cell Division Cycle ◽  
Influenza Virus Replication
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