SHORT COMMUNICATION: Persistence of imazethapyr in two Atlantic Canada soils

1995 ◽  
Vol 75 (4) ◽  
pp. 525-527 ◽  
Author(s):  
K. I. N. Jensen ◽  
J. A. Ivany ◽  
R. R. King
Keyword(s):  
Key Words ◽  
Half Life ◽  
Short Communication ◽  
Limit Of Detection ◽  
Atlantic Canada ◽  
Soil Persistence ◽  
Rotation Crops ◽  
One Year

The half-life of imazethapyr in two Atlantic Canada soils ranged from 19 to 63 d. Soil incorporation increased persistence but residual levels reached or approached the limit of detection (< 5 ng g−1 soil) within 120 d after application of 75 g ha−1 imazethapyr. Sensitive rotation crops were not affected by 75 g ha−1 imazethapyr one year after application. Key words: Imazethapyr, soil persistence, carryover, half-life

DETERMINATION OF AFTER-RIPENING PERIOD AND HORMONAL RESPONSE OF OROBANCHE SOLMSII C.D. CLARKE SEEDS

1970 ◽  
Vol 11 (1) ◽  
Author(s):  
A. Bista ◽  
G. B. Khattri ◽  
B. D. Acharya ◽  
S. C. Srivastava
Keyword(s):  
Growth Hormone ◽  
Seed Germination ◽  
Key Words ◽  
Incubation Period ◽  
Seed Set ◽  
Summer Season ◽  
Conditioning Period ◽  
Root Parasite ◽  
One Year

To find out the ability of Orobanche seeds to germinate immediately after seed set, seeds were germinated periodically at an interval of three months for one year in GR24. Some Orobanche seeds were capable of germination immediately after seed set but most required about nine months as after ripening or incubation period to be able to germinate. The phenomenon of after ripening in Orobanche seeds could be taken as an ecological measure to dormant over following unfavorable wet summer season. The growth hormone studies on Orobanche seed germination have shown that GA3 at a concentration of 100 ppm substantially enhanced seed germination when applied during pre-conditioning period. NAA showed some stimulatory effect at 0.5 - 1.0 ppm when applied during post-conditioning period but the hormone if applied during pre-conditioning period inhibited the germination. Kinetin failed to stimulate the germination at all the concentrations tested. Key words: Germination, root-parasite, hormone. Ecoprint Vol.11(1) 2004.

scholarly journals Quantification of plasma remdesivir and its metabolite GS-441524 using liquid chromatography coupled to tandem mass spectrometry. Application to a Covid-19 treated patient

2020 ◽  
Vol 58 (9) ◽  
pp. 1461-1468 ◽  
Author(s):  
Jean-Claude Alvarez ◽  
Pierre Moine ◽  
Isabelle Etting ◽  
Djillali Annane ◽  
Islam Amine Larabi
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Half Life ◽  
Limit Of Detection ◽  
Treated Patient ◽  
Internal Standard ◽  
Therapeutic Drug ◽  
Active Metabolites ◽  
Limit Of Quantification ◽  
Positive Mode

AbstractObjectivesA method based on liquid chromatography coupled to triple quadrupole mass spectrometry detection using 50 µL of plasma was developed and fully validated for quantification of remdesivir and its active metabolites GS-441524.MethodsA simple protein precipitation was carried out using 75 µL of methanol containing the internal standard (IS) remdesivir-13C6 and 5 µL ZnSO4 1 M. After separation on Kinetex® 2.6 µm Polar C18 100A LC column (100 × 2.1 mm i.d.), both compounds were detected by a mass spectrometer with electrospray ionization in positive mode. The ion transitions used were m/z 603.3 → m/z 200.0 and m/z 229.0 for remdesivir, m/z 292.2 → m/z 173.1 and m/z 147.1 for GS-441524 and m/z 609.3 → m/z 206.0 for remdesivir-13C6.ResultsCalibration curves were linear in the 1–5000 μg/L range for remdesivir and 5–2500 for GS-441524, with limit of detection set at 0.5 and 2 μg/L and limit of quantification at 1 and 5 μg/L, respectively. Precisions evaluated at 2.5, 400 and 4000 μg/L for remdesivir and 12.5, 125, 2000 μg/L for GS-441524 were lower than 14.7% and accuracy was in the [89.6–110.2%] range. A slight matrix effect was observed, compensated by IS. Higher stability of remdesivir and metabolite was observed on NaF-plasma. After 200 mg IV single administration, remdesivir concentration decrease rapidly with a half-life less than 1 h while GS-441524 appeared rapidly and decreased slowly until H24 with a half-life around 12 h.ConclusionsThis method would be useful for therapeutic drug monitoring of these compounds in Covid-19 pandemic.

SHORT COMMUNICATION: Difficulties in using 137Cs to measure erosion in stubble-mulched soil

1995 ◽  
Vol 75 (3) ◽  
pp. 357-359 ◽  
Author(s):  
E. Bremer ◽  
H. H. Janzen ◽  
E. de Jong
Keyword(s):  
Soil Erosion ◽  
Key Words ◽  
Short Communication ◽  
Crop Rotations ◽  
Present Evidence ◽  
Southern Alberta ◽  
Communication Difficulties ◽  
Cesium 137

Soil erosion may be difficult to quantify from redistribution of 137Cs at sites where stubble-mulch techniques were adopted prior to 137Cs deposition, because appreciable 137Cs may have been transported before it was mixed into the soil Ap layer. We present evidence that this occurred in two long-term cropping experiments in southern Alberta. Key words: Cesium-137, tillage, long-term crop rotations, fallow

EFFECT OF CANOPY AND INCORPORATION ON METRIBUZIN PERSISTENCE IN SOILS

1989 ◽  
Vol 69 (3) ◽  
pp. 711-714 ◽  
Author(s):  
K. I. N. JENSEN ◽  
E. R. KIMBALL ◽  
J. A. IVANY
Keyword(s):  
Key Words ◽  
Half Life ◽  
Field Tests ◽  
Soil Surface ◽  
Bare Soil ◽  
Field Conditions ◽  
Row Width ◽  
Sampling Zone

The half-life of metribuzin applied to a bare soil surface was calculated to be 3–7 d over four field tests. An artificial cover erected after application or a shallow incorporation increased the half-life of metribuzin approximately 2.5- to 3-fold. Leaching out of the 0- to 5-cm-deep sampling zone could not account for loss of metribuzin. It was concluded that metribuzin persistence may be affected by volatility and/or photodecomposition losses under field conditions, especially shortly after application. Key words: Metribuzin half-life, volatility, photodecomposition, row width

scholarly journals Asexual Propagation of Eggplant (Solanum melongena L.) through Encapsulated Axillary Buds

1970 ◽  
Vol 19 (2) ◽  
pp. 263-288 ◽  
Author(s):  
A.K.M. N. Huda ◽  
, M.A. Bari ◽  
M. Rahman
Keyword(s):  
Key Words ◽  
Plant Tissue ◽  
Short Communication ◽  
Solanum Melongena ◽  
Axillary Buds ◽  
Synthetic Seed ◽  
Asexual Propagation

 Key words: Auxillary buds, Eggplant, Encapsulation, Synthetic seed D.O.I. 10.3329/ptcb.v19i2.5445 Plant Tissue Cult. & Biotech. 19(2): 263-288, 2009 (December)       - Short communication

Effect of transplanting date on the fatty acid composition, oil content and yield of evening primrose (Oenothera biennis L.) seed

1994 ◽  
Vol 74 (1) ◽  
pp. 129-131 ◽  
Author(s):  
Robert C. Roy ◽  
Peter H. White ◽  
Alex F. More ◽  
John G. Hendel ◽  
Robert Pocs ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Key Words ◽  
Linolenic Acid ◽  
Acid Content ◽  
Oil Content ◽  
Linolenic Acid Content ◽  
Oenothera Biennis ◽  
Evening Primrose ◽  
One Year

The influence of transplanting time on the growth of evening primrose (Oenothera biennis L.) was investigated for 3 yr. Delaying transplanting reduced the yield of seed in two of these years. The amount of oil in the seed was not influenced by time of transplanting, and only in one year did the γ-linolenic acid content of the oil decrease with delays in transplanting. Key words: Evening primrose, transplanting date, oil content, γ-linolenic acid

scholarly journals Delayed replantation: Can it be a success?

1970 ◽  
Vol 6 (4) ◽  
pp. 497-501
Author(s):  
A Parolia ◽  
M Kundabala ◽  
N Shetty ◽  
ST Manuel
Keyword(s):  
Medical Journal ◽  
Case Report ◽  
Key Words ◽  
Male Patient ◽  
Root Canal ◽  
Root Canal Treatment ◽  
Central Incisor ◽  
Maxillary Central Incisor ◽  
One Year

This case report describes delayed replantation of an avulsed maxillary central incisor in a 17-year-old male patient following an injury on fall one day earlier. Avulsed maxillary right permanent central incisor was replanted back into the socket after extra-oral root canal treatment. One year follow up showed validity of treatment, with no evidence of resorption in the replanted tooth. Key words: Replantation, Maxillary central incisor, Resorption doi: 10.3126/kumj.v6i4.1742     Kathmandu University Medical Journal (2008), Vol. 6, No. 4, Issue 24, 497-501     

SHORT COMMUNICATION: Herbicides in surface runoff and groundwater under surface irrigation in southern Alberta

1995 ◽  
Vol 75 (1) ◽  
pp. 145-148 ◽  
Author(s):  
J. J. Miller ◽  
N. Foroud ◽  
B. D. Hill ◽  
C. W. Lindwall
Keyword(s):  
Key Words ◽  
Surface Runoff ◽  
Short Communication ◽  
Surface Irrigation ◽  
Groundwater Samples ◽  
Southern Alberta

In 1991, up to 38 g L−1 hexazinone was found in 50% of surface runoff and 27% of groundwater samples at Lethbridge. No herbicides were detected in surface runoff from irrigation at Taber, but 2,4-D, bromoxynil, dicamba, mecoprop, MCPA and diclofop were found in 48, 34, 21, 16, 13 and 9%, respectively, of groundwater samples, and bromoxynil exceeded the Canadian drinking guideline (5.0 μg L−1) in 11% of samples. Key words: Herbicides, surface irrigation, surface runoff, groundwater

An Assay for the Discrimination of Increased VWF Clearance in VWD.

Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 3478-3478
Author(s):  
Michelle A Stapleton ◽  
Kristi Ladvienka ◽  
Elizabeth Wuitschick
Keyword(s):  
Half Life ◽  
Limit Of Detection ◽  
Performance Testing ◽  
Grey Zone ◽  
Antigen Level ◽  
Factor Activity ◽  
Operating Characteristics ◽  
Patient Sample ◽  
Bleeding History

Abstract Abstract 3478 Poster Board III-415 The quantitative deficiency in von Willebrand Factor (VWF) levels observed in Type 1 VWD can be caused by ineffective synthesis and storage or by a decrease in the half-life of the VWF in the circulation. To date, a number of different point mutations in VWF have been shown to cause a reduced VWF half-life. Clinically it is important to recognize this enhanced clearance phenotype because the increased clearance of VWF can reduce the efficacy of desmopressin treatment in these patients. The VWF propeptide is synthesized as part of a pro-VWF protein and is subsequently cleaved, stored and secreted in an equi-molar ratio with mature VWF. The level of VWF propeptide in the circulation can be used as a marker of VWF synthesis. In individuals with low VWF synthesis, the propeptide level is similarly decreased yielding a propeptide: VWF ratio near 1.0. In individuals with normal levels of VWF synthesis and decreased survival of VWF in circulation, an increased propeptide:VWF ratio is observed. GTI Diagnostics, Inc. (Waukesha, Wisconsin) has developed a fluorescent ELISA for the quantitative measurement of VWF levels and VWF propeptide levels in plasma and for the calculation of a propeptide:VWF ratio. All reagents necessary to run the assay are included in the kit as well as an analysis workbook for easy calculation of results. Assay incubation steps are only 15 minutes, therefore the assay can be completed in 90 minutes. In performance testing the VWF & Propeptide Assay showed excellent within-run, between-run and total imprecision. The limit of detection is 0.02 IU/dL for VWF and 0.02 U/dL for propeptide. The assay range varies depending on the calibrator stock included in the kit however the assay range is at least 1 – 273 IU/dL VWF or U/dL propeptide. No patient sample conditions tested were shown to interfere with the assay. Clinical studies were conducted to evaluate if the VWF & Propeptide Assay can be used to distinguish Type 1 VWD patients with mutations known to cause an increased VWF clearance phenotype (Type 1C) from those without these mutations. One hundred-fifteen Type 1 VWD patients diagnosed on the basis of VWF antigen level, ristocetin co-factor activity, and past bleeding history were tested and 24 Type 1 VWD patients with increased clearance of VWF (Type 1C) diagnosed on the basis of VWF antigen level, ristocetin co-factor activity, past bleeding history, and the presence of a point mutation previously shown to cause increased clearance of VWF. Patients with the following increased clearance mutations were included in the study: R1205H, S2179F, and W1144G (although the majority of the samples contained the R1205H mutation). Using the VWF & Propeptide Assay VWF levels, propeptide levels, and propeptide:VWF ratios were determined for each patient sample. The propeptide:VWF ratios were used to determine an appropriate diagnostic cutoff by receiver operating characteristics (ROC) curve analysis. From the ROC analysis, a propeptide:VWF ratio cutoff value of ≥3.3 provided optimal clinical sensitivity and specificity when distinguishing between Type 1 VWD and Type 1 VWD with increased VWF clearance (Type 1C). Using the ratio cutoff of ≥3.3 yielded 100.0% sensitivity, characterizing all known Type 1C patients correctly and yielded 97.4% specificity, where 3 Type 1 patients were characterized as Type 1C. Two of the 3 mischaracterized patients had Type O blood and the blood group of the third sample was unknown. Since it has been demonstrated that patients with a Type O blood generally have a lower VWF level and correspondingly a slightly elevated propeptide:VWF ratio, we suggest the use of the following grey zone. Propeptide:VWF ratios of 3.3 – 4.1 may be due to increased VWF clearance or the result of a Type 1 VWD patient with Type O blood. Ratios of ≥ 4.2 are indicative of Type 1C VWD. Disclosures: Stapleton: GTI Diagnostics: Employment. Ladvienka:GTI Diagnostics: Employment. Wuitschick:GTI Diagnostics: Employment.

scholarly journals Endocrine Responses to Overreaching Before and After 1 Year of Weightlifting

1994 ◽  
Vol 19 (4) ◽  
pp. 400-410 ◽  
Author(s):  
Andrew C. Fry ◽  
William J. Kraemer ◽  
Scott E. Gordon ◽  
Michael H. Stone ◽  
Beverly J. Warren ◽  
...  
Keyword(s):  
Training Program ◽  
Key Words ◽  
Endocrine System ◽  
Prior Exposure ◽  
Training Volume ◽  
Key Words Testosterone ◽  
Before And After ◽  
Exercise Induced ◽  
One Year

Nine elite male junior weightlifters (mean age 17.6 ± 0.3 yrs) performed weightlifting tests before (Test 1) and after (Test 2) 1 week of increased training volume (overreaching) and repeated the protocol after 1 year of their training program. Strength increased by Year 2 (p < 0.05) but did not change during either week of increased training volume. The 1-week overreaching stimulus resulted in attenuated exercise-induced testosterone concentrations during Year 1, but augmented exercise-induced testosterone concentrations during Year 2. Testosterone concentrations at 7 a.m. decreased for only Year 1. For both years, the 1-week overreaching stimulus increased Cortisol at 7 a.m., indicative of the increased training volumes. Testosterone/Cortisol was not affected by increased training volume for either year. One year of chronic weightlifting and prior exposure to the overreaching stimulus appears to decrease the detrimental effects of stressful training on the endocrine system. Key words: testosterone, Cortisol, weightlifting, overtraining

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