Analysis of tissues from normal lambs and those with spider syndrome

1994 ◽  
Vol 74 (3) ◽  
pp. 583-585 ◽  
Author(s):  
T. Nakano ◽  
B. Walker ◽  
B. A. Young

This study was undertaken to examine tissue abnormalities in sheep with spider lamb syndrome (SLS). The major skeletal abnormalities found in SLS animals were cartilage erosion and bone abnormalities with large amounts of cartilaginous tissues present in the spongy bone (chondrodysplasia). Eroded cartilage contained lower (P < 0.05) than normal concentrations of both collagen and proteoglycan. Key words: Spider lamb syndrome, cartilage, bone, sheep

Author(s):  
Rania Zeitoun ◽  
Mohammed Saleh Ali Mohieddin

Abstract Background The value of adding coronal STIR images to MR imaging of sciatica aiming to detect extra-spinal abnormalities. Results Additional coronal STIR images detected extra-spinal abnormalities in 20% of the patients, thereby downgraded the normal studies from 21 to 13%. The extra-spinal abnormalities included bone abnormalities (36.4%), soft tissue abnormalities (4.5%), neurological abnormalities (2.3%), gynecological abnormalities (50%), and miscellaneous (6.8%). In 6.9% of patients, the extra-spinal abnormalities explained the patients’ pain and influenced their management. Extra-spinal causes of pain significantly correlated to positive trauma and neoplasm history, normal routine protocol images, and absent nerve root impingement. Extra-spinal abnormalities were more prevalent in age groups (20–39 years). Conclusion Coronal STIR images (field of view: mid abdomen to the lesser trochanters) identify extra-spinal abnormalities that maybe overlooked on routine MRI protocol. It is of additional value in young adults, trauma, neoplasm, and negative routine images.


1997 ◽  
Vol 38 (5) ◽  
pp. 759-769 ◽  
Author(s):  
D. Grant ◽  
W. F. Blazak ◽  
G. L. Brown

Purpose: The reproductive toxicology of mangafodipir trisodium (MnDPDP, Teslascan), a new hepatobiliary MR contrast agent, was evaluated in rats and rabbits. Material and Methods: Male and female fertility and post-natal development were examined in rats after repeated i.v. injections of MnDPDP. The developmental toxicity in rats was investigated after repeated daily i.v. injections during organogenesis with MnDPDP, MnCl2, or DPDP, as well as with MnCl2, administered orally. The developmental toxicity of i.v. injected MnDPDP was also investigated in rabbits. Results: MnDPDP (100 μmol/kg) had no adverse effects on rat fertility. However, both MnDPDP (10–40 μmol/kg) and MnCl2 (30 μmol/kg) caused skeletal abnormalities in the rat, but not in the rabbit given 20 μmol MnDPDP/kg. Maternal treatment of rats with MnDPDP (40 μmol/kg) reduced survival and body weights of neonates, and adversely affected their functional, but not physical development. No skeletal abnormalities were seen in the rat after i.v. administered DPDP (40 μmol/kg) or MnCl2 (6 μmol/kg), or after MnCl2 (400 μmol/kg) given by oral gavage. Maternal toxicity was not seen in rats or rabbits given these doses. Conclusion: MnDPDP caused skeletal abnormalities in foetal rats, but not rabbits, and had no effects on rat fertility. Manganese appears to be the causative agent for inducing bone abnormalities in the rat.


2018 ◽  
pp. 3-14

Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the digestive tract (1%). These tumors express the CD 117 in 95% of cases. The stomach is the preferential localization (70%). Diagnosis is difficult and sometimes late. Progress of imaging has greatly improved the management and the prognosis. Computed tomography (CT) is the gold standard for diagnosis, staging, and treatment follow-up. The increasing recognition of GIST’s histopathology and the prolonged survival revealed some suggestive imaging aspects. Key words: gastro-intestinal stromal tumors; computed tomography; diagnosis


Author(s):  
Prof.RAE Aliev Z.H.

The current information on moisture and the temperature of the ground in managerial system by production to agricultural product necessary, in the first place, for taking the operative decisions at development ecological clean technology irrigation under growing agricultural cultures to achieve the maximum harvest. Key words: aerospace methods, COW, moisture, moisture test, arable, soil, ecology, vafer humidity, drill, graduation, tool, etc.


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