Comparaison de l'effet de deux analogues de la prostaglandine F2α sur la synchronisation de l'œstrus chez la vache de boucherie

1994 ◽  
Vol 74 (1) ◽  
pp. 29-36 ◽  
Author(s):  
G. Laverdière ◽  
J. J. Dufour ◽  
G. L. Roy ◽  
D. Lavoie ◽  
J. Proulx

The objective of this study was to compare the efficiency of cloprostenol and fenprostalene in synchronizing estrus. Before treatment, estrus was detected during 4.5 d for multiparous cows in exp. 1 (n = 105) and 7.5 d for primiparous and nulliparous females in exp. 2 (n = 86). Females that were not in estrus (exp. 1: n = 74 and exp. 2: n = 58) received at random, either 500 μg of cloprostenol (i.m.) or 1 mg of fenprostalene (s.c). Cattle synchronized with cloprostenol or fenprostalene that presented estrus within 5 d showed similar fertility rates (exp. 1: 86.1% vs. 88.0% and exp. 2: 89.3% vs. 72.2% for cloprostenol and fenprostalene, respectively) and PGF2α-estrus intervals (exp. 1: 68 h vs. 73 h and exp. 2: 57 h vs. 57 h). However, the incidence of synchronization (exp. 1: 97.3% vs. 67.6%, P < 0.001; and exp. 2: 93.3% vs. 64.3%, P < 0.01) and pregnancy rates (exp. 1: 83.8% vs. 59.5%, P < 0.05; and exp. 2: 83.3% vs. 46.4%, P < 0.01) were statistically higher for cloprostenol than for fenprostalene. In exp. 2, primiparous cows and heifers obtained similar reproductive performances. The fertility rate of cattle treated with cloprostenol in exp. 2 was higher than that of untreated cattle (89.3% vs. 50.0%, P < 0.001, n = 56). In exp. 1, the variance of interval to estrus was similar for both analogues, but in exp. 2, it was less variable after the administration of cloprostenol (P < 0.05). Intervals between cloprostenol injection and estrus (0–10 and 0–15 d) were shorter (P < 0.05) and less variable (P < 0.001) than fenprostalene–estrus intervals. These results indicate that cloprostenol has a better potential for estrus synchronization than fenprostalene. Key words: Cloprostenol, fenprostalene, estrus synchronization, prostaglandin F2α, beef cattle

2001 ◽  
Vol 81 (3) ◽  
pp. 335-343 ◽  
Author(s):  
J. A. Small ◽  
J. D. Ambrose ◽  
W. P. McCaughey ◽  
D. R. Ward ◽  
W. D. Sutherland ◽  
...  

Trials were conducted in the spring (May; n = 324) and fall (October; n = 132) with crossbred continental-type beef cows assigned on the basis of parity and postpartum interval to one of three timed-AI treatments and one of two post-AI treatments. The timed-AI treatments were: (DPG) double (14 d apart) PGF2α (Lutalyse®) and AI (day = 0) 72 h after the second PGF2α (day –3); (OVS) Ovsynch® with the second GnRH (Factrel®) at 48 h and AI at 66 h; and (BRC) the same as OVS except that the second GnRH was given at the time of AI. Half of the cows within each treatment were given GnRH on day 14. Plasma progesterone concentrations were determined for the day of the first injection and on days –3, 0, 14, and 21. Timed-AI pregnancy was diagnosed by ultrasonography at day 42 and confirmed at calving. For DPG, OVS and BRC, PGF2α responder rates were 75.9, 51.4 and 71.3%, respectively, in spring (P < 0.05) and 70.4, 70.4 and 59.1% in fall (P > 0.05), and AI pregnancy rates were 28.7, 44.9 and 44.4% in spring (P< 0.05) and 25.0, 40.9 and 43.2% in fall (P > 0.05). Post-AI GnRH had no significant effect on pregnancy or conception rates or day 21 progesterone. The use of GnRH in the PGF2α based timed-AI program improved pregnancy rates and the BRC treatment was as effective as OVS. Neither postpartum interval nor initial progesterone concentration influenced (P >0.05) the effect of GnRH on AI pregnancy rate, and GnRH had no effect (P > 0.05) on twinning rate or gender ratio. Key words: Beef cows, estrous synchronization, pregnancy, timed-AI, progesterone


1988 ◽  
Vol 68 (4) ◽  
pp. 1301-1304 ◽  
Author(s):  
R. D. H. COHEN ◽  
B. D. KING ◽  
E. D. JANZEN

Heifers injected with prostaglandin F2α had significantly higher pregnancy and conception rates within 11 d of start of breeding than noninjected heifers; 56.9 vs. 45.5 pregnancy as a percent of heifers exposed (P < 0.05) and 74.1 vs. 58.2 conception as a percent of pregnant heifers (P < 0.005). Data were pooled for 422 heifers over 5 yr. However, there were no significant effects on calving distribution or weaning weights of their calves. Key words: Prostaglandin F2α, natural breeding, heifer, estrus synchronization


1999 ◽  
Vol 79 (1) ◽  
pp. 39-43 ◽  
Author(s):  
J. Thundathil ◽  
J. P. Kastelic ◽  
W. O. Olson ◽  
R. B. Cook ◽  
R. J. Mapletoft

Three experiments were conducted with suckled crossbred beef cows to determine the efficacy of various short-term regimens for synchronizing estrus or ovulation and to determine whether feeding melengestrol acetate (MGA) after timed AI will increase pregnancy rate. In exp. 1, all cows (n = 141) were given 0.5 mg MGA head−1 d−1 for 7 d (days 1 to 7), 1 or 5 mg E17β (and 100 mg progesterone) or 100 µg GnRH on day 1, and 500 µg cloprostenol on day 7. There were no significant differences among groups for estrous or synchronized conception rates (average, 84.4 and 52.1%, respectively). With an identical protocol in exp. 2 (78 cows), by day 11, cows given 5 mg E17β had the highest estrous and synchronized pregnancy rates (65.4 and 42.3%), compared to 1 mg E17β (46.2 and 15.4%) and GnRH (34.6 and 11.5%). Cows not detected in estrus were timed-inseminated and given 100 µg GnRH, 100 h after cloprostenol. There were no significant differences among groups for synchronized conception rate to timed AI (65.0%) or synchronized pregnancy rate to all inseminations (56.4%). Overall, 5 mg E17β gave the most consistent results. In exp. 3, 84 cows were given 100 µg GnRH on days 1 and 9, 500 µg cloprostenol on day 7, and were timed-inseminated on day 10. Half were fed MGA (0.5 mg head−1 d−1) on days 16 to 22, but the pregnancy rate was not different from that in the remaining cows (55.0 versus 47.8%, P > 0.5). Key words: Ovary, follicles, estrus synchronization, beef cows


1998 ◽  
Vol 78 (3) ◽  
pp. 437-439
Author(s):  
L. A. Stephens ◽  
R. Rajamahendran

This study compared the use of two injections of prostaglandin F2α(PGF2α) given 11 d apart with the use of gonadotropin releasing hormone (GnRH) followed by PGF2α after 7 d for synchronizing estrus in beef heifers. Heifers synchronized with GnRH and PGF2α showed weak signs of estrus and were more difficult to inseminate. There were no significant differences in synchronization rate and pregnancy rate. Key words: Estrus synchronization, beef heifers, gonadotropin releasing hormone, prostaglandin F2α


1997 ◽  
Vol 77 (4) ◽  
pp. 683-688 ◽  
Author(s):  
J. P. Kastelic ◽  
D. H. McCartney ◽  
W. O. Olson ◽  
A. D. Barth ◽  
R. J. Mapletoft

Four experiments were conducted to investigate the use of melengesterol acetate (MGA) and estradiol-17β (E-17β) for synchronizing estrus and improving reproductive performance in beef cattle. Synchronized pregnancy rates were higher (P < 0.05) in heifers fed MGA after AI than controls (4 of 9 versus 0 of 7, respectively), but were not different for cows (20 of 37, 54% versus 23 of 40, 58%). Estrus rate (percentage of cows detected in estrus) was higher (P < 0.05) for cows treated with E-17β + MGA compared with those treated with cloprostenol alone (85.0 versus 65.9%). Synchronized pregnancy rates were not significantly affected by feeding MGA or grain only after detected estrus and AI (20 of 31, 64% versus 17 of 30, 57%). For 20 cows not detected in estrus and bred 100 h after cloprostenol treatment, pregnancy rate was higher (P < 0.05) for those fed MGA after AI than controls (6 of 11, 54% versus 1 of 9, 11%). Feeding MGA after breeding may help to improve pregnancy rates. Key words: Melengesterol acetate, estradiol-17β, estrus, reproductive performance, beef cattle


Author(s):  
Juan Patricio Anchordoquy ◽  
Santiago Nicolás Lorenti ◽  
Gustavo Sebastián Polero ◽  
Nicolás Agustín Farnetano ◽  
Diana Esther Rosa ◽  
...  

2002 ◽  
Vol 74 (3) ◽  
pp. 547-552 ◽  
Author(s):  
D. Cavestany ◽  
N. Negrin ◽  
R. Negrin ◽  
J. F. Groth

AbstractThe objective was to evaluate different oestrous synchronization schemes in beef cattle under range conditions. In experiment 1, 202 heifers averaging 26 months of age were assigned randomly to three treatments: (a) GnRH-PG. (no. = 44) day 0 (D0): injection of GnRH; D7: injection of PGF2α; D0 to D25 oestrous detection (OD) and artificial insemination (AI); (b) OD-PG. (no. = 45) D0 to D4; OD + AI; D5: injection of PGF2α; D5 to D25 OD + AI; and (c)Ovsynch. (no. = 113) D0: injection of GnRH; D7: injection of PGF2α; D9: injection of GnRH and 16 h later AI at fixed time. In experiment 2, 318 non-suckling cows were assigned randomly to three treatments: (a) GnRH-PG. (no. = 106) D0: injection of GnRH; D7: injection of PGF2α; D0 to D25 OD + AI; (b) GnRH-MAP-PG. (no. = 106) D0: injection of a GnRH analogue and insertion of an intravaginal sponge impregnated with 250 mg of medroxyprogesterone acetate; D7: injection of PGF2α and sponge withdrawal; D0 to D25 OD + AI; (c) controls. (no. = 106) OD and AI. The experimental period lasted 25 days and, with exception of the Ovsynch treatment, oestrous detection was carried out twice a day (a.m./p.m.) and inseminations performed 12 h later. The pregnancy rates assessed by ultrasonography 30 days after AI were: experiment 1: (a) 30·0%; (b) 28·6% and (c) 62·3% (P < 0·05); experiment 2: (a) 60·2%; (b) 57·8% and (c) 45·5% (P < 0·05). It is concluded that in heifers and non-suckling cows, oestrous synchronization treatments result in higher pregnancy rates. In non-suckling cows, the addition of a progestagen did not improve the response.


2016 ◽  
Vol 28 (7) ◽  
pp. 1004 ◽  
Author(s):  
Juliana C. Borges-Silva ◽  
Márcio R. Silva ◽  
Daniel B. Marinho ◽  
Eriklis Nogueira ◽  
Deiler C. Sampaio ◽  
...  

This study evaluated the use of cooled semen in a fixed-time artificial insemination (FTAI) program compared with frozen–thawed semen to improve pregnancy rates in beef cattle. Ejaculates of three bulls were collected and divided into two treatments: (1) frozen–thawed semen and (2) cooled semen. Egg-yolk extender without glycerol was used for the cooled semen treatment. Straws (25 × 106 spermatozoa) were submitted to cooling for preservation at 5°C for 24 h, after which FTAI was performed. Nelore cows (n = 838) submitted to FTAI were randomly inseminated using frozen–thawed semen or cooled semen. There was a 20% increase in the pregnancy per AI (P AI–1) using cooled semen compared with frozen–thawed semen (59.9 ± 4.7 vs 49.4 ± 5.0%; P < 0.005). There was no difference in P AI–1 among the bulls (P = 0.40). The frozen–thawed semen had fewer functional spermatozoa than did the cooled semen when evaluated by sperm motility (61.7 vs 81.0%), slow thermoresistance test (41.7 vs 66.7%) and hypoosmotic swelling test (38.3 vs 53.7%; P < 0.05). The percentage of sperm abnormalities did not differ between the freeze–thawing and cooling processes (18.6 vs 22.1%; P > 0.05). Because there was less damage to spermatozoa and improvement in P AI–1, the use of cooled semen instead of frozen–thawed semen is an interesting approach to increase reproductive efficiency in cattle submitted to a FTAI protocol.


2020 ◽  
Vol 89 (4) ◽  
pp. 307-315
Author(s):  
Hasan Alkan ◽  
Huseyin Erdem

The aim of this study was to investigate the effects of hormonal support on the pregnancy rate in repeat breeder cows. Prostaglandin F2α + Ovsynch oestrus synchronization protocol was applied to the cows. Following the fixed time insemination (day 0), the cows were divided into 4 groups. In Group 1 (n = 42), progesterone releasing intravaginal device (PRID) was placed vaginally at 84 h and removed on the 9th day after the artificial insemination. In Group 2 (n = 40), the cows were administered human chorionic gonadotropin (hCG) on the 7th day. Group 3 (n = 45) was applied a combination of progesterone and hCG. Group 4 (n = 42) was not given any treatment. Blood samples were collected from all cows 4 times on days 3.5, 7, 12, and 18 to evaluate progesterone concentrations. The pregnancy rates were 40.47%, 37.50%, 44.44%, and 30.95% in Group 1, 2, 3, and 4, respectively (P > 0.05). In addition, in cows with progesterone concentrations <2 ng/ml on day 3.5, the pregnancy rates were found to be lower than in the cows with progesterone concentrations >2 ng/ml in Group 4 (P < 0.05). Progesterone supplementation in cows with progesterone concentrations < 2 ng/ml appeared to increase pregnancy rates (P < 0.05) in Groups 1 and 3. As a result, post-insemination hormonal applications in the repeat breeder cows did not increase the pregnancy rate. However, it was concluded that determination of progesterone concentrations on day 3.5 following artificial insemination and then hormonal support in the cows with low concentrations would increased the pregnancy rate.


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