scholarly journals INFLUENCE OF CECECTOMY AND DIETARY ANTIBIOTICS ON THE FATE OF INGESTED INTACT GLUCOSINOLATES IN POULTRY

1987 ◽  
Vol 67 (4) ◽  
pp. 1117-1124 ◽  
Author(s):  
B. A. SLOMINSKI ◽  
L. D. CAMPBELL ◽  
N. E. STANGER
Keyword(s):  
Key Words ◽  
Canola Meal ◽  
Absolute Amount ◽  
Gi Tract ◽  
Balance Study ◽  
Thiocyanate Ion ◽  
Series Of Experiments ◽  
The Absolute

A series of experiments involving the use of cecectomized hens and dietary antibiotics as means of controlling hindgut fermentation was conducted to follow the disappearance of intact glucosinolates (IG) from the GI tract of poultry. In addition, a balance study was conducted with colostomized roosters to determine the role of the kidney in the excretion of IG and thiocyanate ion (SCN). Recovery of IG in cecectomized hens was significantly (P < 0.05) higher than in intact hens (80.5 vs. 33.6 mmol 7 d−1). Similarly, IG recovery was significantly (P < 0.05) higher in antibiotic-fed hens than in hens fed no antibiotics. The effect varied among antibiotics with chlorotetracycline and lincomycin showing the greatest response. Both aliphatic and aromatic (glucosinalbin and indoles) IG disappeared from the GI tract to a significantly (P < 0.01) greater extent in intact hens than in cecectomized hens but the absolute amount of disappearance was greater for aliphatic IG than for aromatic IG. Thiocyanate ion (SCN) excretion was high in the urine of colostomized roosters fed canola meal and exceeded intake in antibiotic-fed, cecectomized hens. The biotransformation of absorbed aliphatic IG was indicated as a possible source of the excess SCN. Key words: Poultry, glucosinolates, absorption, cecectomy, antibiotics, thiocyanate ion

Factors affecting the nutritional value of canola meal: A review

1993 ◽  
Vol 73 (4) ◽  
pp. 689-697 ◽  
Author(s):  
J. M. Bell
Keyword(s):  
Plant Breeding ◽  
Key Words ◽  
Nutritional Value ◽  
Economic Value ◽  
Canola Meal ◽  
Nutritional Factors ◽  
Factors Affecting ◽  
Available Energy ◽  
Potential Impact

In this review canola meal (CM), its nutritionally significant components and the availability of its nutrients to poultry, pigs and cattle were discussed. Avenues for possible improvement in available energy, protein and lysine were identified. Recent findings on glucosinolates were also discussed with the conclusion that a further reduction of glucosinolates through plant breeding is both possible and desirable. The role of the anti-nutrients sinapine, tannins and phytic acid were also considered. The potential impact of improvements to CM on its economic value was examined using linear program least-cost ration formulations applied to typical market situations. Key words: Canola meal, energy, protein, carbohydrates, anti-nutritional factors, economics

scholarly journals HubP, a Polar Landmark Protein, Regulates Flagellar Number by Assisting in the Proper Polar Localization of FlhG in Vibrio alginolyticus

2016 ◽  
Vol 198 (22) ◽  
pp. 3091-3098 ◽  
Author(s):  
Norihiro Takekawa ◽  
Soojin Kwon ◽  
Noriko Nishioka ◽  
Seiji Kojima ◽  
Michio Homma
Keyword(s):  
Marine Bacterium ◽  
Vibrio Alginolyticus ◽  
Absolute Amount ◽  
Negative Regulators ◽  
Content Type ◽  
Polar Localization ◽  
Cell Pole ◽  
The Absolute ◽  
Flagellar Biogenesis

ABSTRACT The marine bacterium Vibrio alginolyticus has a single polar flagellum, the number of which is regulated positively by FlhF and negatively by FlhG. FlhF is intrinsically localized at the cell pole, whereas FlhG is localized there through putative interactions with the polar landmark protein HubP. Here we focused on the role of HubP in the regulation of flagellar number in V. alginolyticus . Deletion of hubP increased the flagellar number and completely disrupted the polar localization of FlhG. It was thought that the flagellar number is determined primarily by the absolute amount of FlhF localized at the cell pole. Here we found that deletion of hubP increased the flagellar number although it did not increase the polar amount of FlhF. We also found that FlhG overproduction did not reduce the polar localization of FlhF. These results show that the absolute amount of FlhF is not always the determinant of flagellar number. We speculate that cytoplasmic FlhG works as a quantitative regulator, controlling the amount of FlhF localized at the pole, and HubP-anchored polar FlhG works as a qualitative regulator, directly inhibiting the activity of polar FlhF. This regulation by FlhF, FlhG, and HubP might contribute to achieving optimal flagellar biogenesis at the cell pole in V. alginolyticus . IMPORTANCE For regulation of the flagellar number in marine Vibrio , two proteins, FlhF and FlhG, work as positive and negative regulators, respectively. In this study, we found that the polar landmark protein HubP is involved in the regulation of flagellar biogenesis. Deletion of hubP increased the number of flagella without increasing the amount of pole-localizing FlhF, indicating that the number of flagella is not determined solely by the absolute amount of pole-localizing FlhF, which is inconsistent with the previous model. We propose that cytoplasmic FlhG and HubP-anchored polar FlhG negatively regulate flagellar formation through two independent schemes.

Transisi Kepemimpinan Dalam Alkitab

2016 ◽  
Vol 1 (1) ◽  
pp. 16-38
Author(s):  
Jonathan Octavianus
Keyword(s):  
New Testament ◽  
Old Testament ◽  
Jesus Christ ◽  
Transition Time ◽  
People Of God ◽  
The Absolute

As every epoch there are there a transition time, on Old Testament like Moses with Joshua, Joshua selected by God an supported fully by Moses, Conversely Moses have liberally to be changed. Like Elijah to Elisha too.Pattern on New Testament there are an examples of transition time too, like Jesus Christ to His Disciples, an transition from Paul to his successor Timothy. This is a heart and soul a big leader, and shall all leadership owners shepherd in church, Christian institution, etc.Which most be remembered in transition of leadership, that people of God leadership, about who will lead, who continue leadership, like a principle in biblical, hence a role of God, is determinant an anoint man which be selected the absolute God choice and constitute all other, but a succession router leader is which have been selected His own. An can be anointed in front of believers.

THE ROLE OF COMMUNICATIVE AND FUNCTIONAL APPROACH IN THE TRANSLATION OF SCIENTIFIC AND TECHNICAL LITERATURE (Ukrainian — German discourse)

2019 ◽  
Vol 26 (27) ◽  
pp. 68-74
Author(s):  
Svitlana Gruschko
Keyword(s):  
Key Words ◽  
Information Exchange ◽  
Functional Approach ◽  
Communication Structure ◽  
Technical Literature ◽  
Translation Strategy ◽  
Purposeful Activity

The article investigates the role of communicative-functional approach in the translation of scientific and technical literature, when the translation itself is seen as a tool to accomplish purposeful activity of communicators, representatives of different interlingual groups. In practical terms, the difficulties of translating scientific and technical texts are due to the peculiarities of scientific style, insufficient understanding of the terminology of a particular field of knowledge, which complicates the choice of adequate translation solutions. In this context, an important role is played by the translation strategy, where the communicativefunctional approach dominates. The translation is implicitly included in the communication structure between the author and the recipient. The relevance of the article is determined by the necessity of studying the problems of scientific and technical literature translation, taking into account the current realities of interlanguage information exchange. Key words: communicative-functional approach, interlingual communication, translation, structure

INTERPRETATIONAL FIELD OF THE CONCEPT “WOMAN” IN ENGLISH AND KYRGYZ LINGUOCULTURES

2019 ◽  
pp. 54-56
Author(s):  
Баяманова М.С.
Keyword(s):  
Comparative Study ◽  
Key Words ◽  
Analytical Data ◽  
Semantic Field ◽  
Traditional Values ◽  
Lexical Unit ◽  
Semantic Fields ◽  
Field Culture

Summary: The article deals with the analysis of the interpretational field of the basic lexical units which represent the meaning of the concept “woman” in English and Kyrgyz languages and cultures. Comparative – contrastive analytical data of the most frequently used in both languages variants of the interpretation of the concept “woman” have been given. The semantic fields of nuclear and nearnuclear meanings of the lexical units, transforming the notion of “woman” in English and Kyrgyz languages and also the place and role of these notions in cultures and philosophy of the nations on the basis of mentality and traditional values have been studied and described. The situations of the use of this or that variant of the meaning of lexical unit. A comparative study of the definitions of the word “woman’ in English and Kyrgyz languages have been given. Key words: concept, woman, interpretational field, notion, definition, semantic field, culture, language, linguoculture, transformation Аннотация: В статье рассматриваются интерпретационные поля основных лексических единиц, репрезентирующих значение концепта «женщина» в английской и кыргызской лингвокультурах. Приводятся сравнительно-сопоставительные аналитические данные наиболее употребительных в речи обоих языков вариантов интерпретации концепта «женщина». Изучены и описаны семантические поля ядерных и околоядерных значений лексических единиц, трансформирующих понятие «женщина» в английском и кыргызском языке, а также роль и место этих понятий в культурах и философии народов на основе менталитета и традиционных ценностей. Приводятся ситуации использования того или ино- го варианта значения лексической единицы, проведено сравнительное изучение определений слова «женщина» в английском и кыргызском языках. Ключевые слова: концепт, женщина, интерпретационное поле, понятие, определение, семантическое поле, культура, язык, лингвокультура, трансформация Аннотация: Макалада англис жана кыргыз тилдеринде жана маданияттарында «аял» концептинин маанисин репрезентациалаган негизги лексикалык бирдиктер каралат. «Аял» концептин эки тилдеги кѳп колдонулуучу интерпретациялоо варианттарынын аналитикалык салыштырма маалыматтары изил- делип берилген. Англис жана кыргыз тилдеринде «аял» түшүнүгүн трансформациялаган лексикалык бирдиктердин түп нуска жана ага жакындашкан маанилери иликтелип каралган. Берилген түшүнүктѳрдүн элдик философиясында жана маданиятында, менталитеттин жана салттын негизинде эл арасына кеӊири тараган, элдик тилде жана маданиятта ойногон ролу менен орду чагылдырылган. Ар түрдү ситацияларда колдонулуучу тиги же бул лексикалык бирдиктердин маанисинин варианттары каралган, «аял» деген сѳздун англис жана кыргыз тилдериндеги түшүндүрмѳлѳрү салыштырылып изилделген. Түйүндүү сѳздѳр: концепт, аял, интерпретациялоо мейкиндиги, түшүнүк, түшүндүрмѳ, семантикалык чѳйрѳ, маданият, тил, лингвомаданият, трансформациялоо

scholarly journals The role of faint population III supernovae in forming CEMP stars in ultra-faint dwarf galaxies

2021 ◽  
Author(s):  
Myoungwon Jeon ◽  
Volker Bromm ◽  
Gurtina Besla ◽  
Jinmi Yoon ◽  
Yumi Choi
Keyword(s):  
Milky Way ◽  
Dwarf Galaxies ◽  
Mass Resolution ◽  
Explosion Energy ◽  
High Carbon ◽  
Cosmological Simulations ◽  
Carbon Abundance ◽  
The Absolute ◽  
Zoom In

Abstract CEMP-no stars, a subset of carbon enhanced metal poor (CEMP) stars ($\rm [C/Fe]\ge 0.7$ and $\rm [Fe/H]\lesssim -1$) have been discovered in ultra-faint dwarf (UFD) galaxies, with Mvir ≈ 108 M⊙ and M* ≈ 103 − 104 M⊙ at z = 0, as well as in the halo of the Milky Way (MW). These CEMP-no stars are local fossils that may reflect the properties of the first (Pop III) and second (Pop II) generation of stars. However, cosmological simulations have struggled to reproduce the observed level of carbon enhancement of the known CEMP-no stars. Here we present new cosmological hydrodynamic zoom-in simulations of isolated UFDs that achieve a gas mass resolution of mgas ≈ 60 M⊙. We include enrichment from Pop III faint supernovae (SNe), with ESN = 0.6 × 1051 erg, to understand the origin of CEMP-no stars. We confirm that Pop III and Pop II stars are mainly responsible for the formation of CEMP and C-normal stars respectively. New to this study, we find that a majority of CEMP-no stars in the observed UFDs and the MW halo can be explained by Pop III SNe with normal explosion energy (ESN = 1.2 × 1051 erg) and Pop II enrichment, but faint SNe might also be needed to produce CEMP-no stars with $\rm [C/Fe]\gtrsim 2$, corresponding to the absolute carbon abundance of $\rm A(C)\gtrsim 6.0$. Furthermore, we find that while we create CEMP-no stars with high carbon ratio $\rm [C/Fe]\approx 3-4$, by adopting faint SNe, it is still challenging to reproduce CEMP-no stars with extreme level of carbon abundance of $\rm A(C)\approx 7.0-7.5$, observed both in the MW halo and UFDs.

scholarly journals The Absolute as the Meeting Point Between Speculation and Fiction

2020 ◽  
Vol 3 (1) ◽  
pp. 349-357 ◽  
Author(s):  
Daina Habdankaitė
Keyword(s):  
Science Fiction ◽  
Significant Role ◽  
Meeting Point ◽  
Weird Fiction ◽  
Weak Points ◽  
The Absolute

AbstractThe article investigates Meillassoux’s notion of the absolute in relationship with the Kantian and Hegelian philosophical systems. The absolute, as independent of subjective consciousness, is showcased as the meeting point of speculation and fiction. By looking into Meillassoux’s notions of speculation and some works of weird fiction, it is argued that the significant role of imagination as well as a deferred temporality is what facilitates the discussion of both speculation and fiction as faculties able to transcend the limitations that are projected by the correlationist mind. Through a reading of Lovecraftian fiction, both the strong and weak points of Meillassoux’s argumentation in After Finitude and Science Fiction and Extro-Science Fiction are identified, proving the latter to be a less successful way of grasping the chaotic real.

scholarly journals Exploring Mucin as Adjunct to Phage Therapy

2021 ◽  
Vol 9 (3) ◽  
pp. 509
Author(s):  
Amanda Carroll-Portillo ◽  
Henry C. Lin
Keyword(s):  
Pathogenic Bacteria ◽  
Structural Changes ◽  
Phage Therapy ◽  
Bacterial Species ◽  
Gi Tract ◽  
Beneficial Bacteria ◽  
Phage Cocktail ◽  
Small Intestinal ◽  
Gastrointestinal Dysbiosis

Conventional phage therapy using bacteriophages (phages) for specific targeting of pathogenic bacteria is not always useful as a therapeutic for gastrointestinal (GI) dysfunction. Complex dysbiotic GI disorders such as small intestinal bowel overgrowth (SIBO), ulcerative colitis (UC), or Crohn’s disease (CD) are even more difficult to treat as these conditions have shifts in multiple populations of bacteria within the microbiome. Such community-level structural changes in the gut microbiota may require an alternative to conventional phage therapy such as fecal virome transfer or a phage cocktail capable of targeting multiple bacterial species. Additionally, manipulation of the GI microenvironment may enhance beneficial bacteria–phage interactions during treatment. Mucin, produced along the entire length of the GI tract to protect the underlying mucosa, is a prominent contributor to the GI microenvironment and may facilitate bacteria–phage interactions in multiple ways, potentially serving as an adjunct during phage therapy. In this review, we will describe what is known about the role of mucin within the GI tract and how its facilitation of bacteria–phage interactions should be considered in any effort directed at optimizing effectiveness of a phage therapy for gastrointestinal dysbiosis.

Stochastic pumping of non-equilibrium steady-states: how molecules adapt to a fluctuating environment

2018 ◽  
Vol 54 (5) ◽  
pp. 427-444 ◽  
Author(s):  
R. D. Astumian
Keyword(s):  
Steady States ◽  
Absolute Amount ◽  
Fluctuating Environment ◽  
The Absolute ◽  
Non Equilibrium

Fluctuations favour state B = (B,B′) based on kinetic asymmetry combined with moderate dissipation rather than state A = (A,A′) in which the absolute amount of dissipation is greater but where there is no kinetic asymmetry.

scholarly journals The Emerging Role of Polyphenols in the Management of Type 2 Diabetes

Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 703
Author(s):  
Yao Wang ◽  
Hana Alkhalidy ◽  
Dongmin Liu
Keyword(s):  
Type 2 Diabetes ◽  
Glucose Homeostasis ◽  
Gut Hormones ◽  
Nutritional Regulation ◽  
Gi Tract ◽  
Cell Dysfunction ◽  
Glucagon Like Peptide 1 ◽  
Metabolic Action

Type 2 diabetes (T2D) is a fast-increasing health problem globally, and it results from insulin resistance and pancreatic β-cell dysfunction. The gastrointestinal (GI) tract is recognized as one of the major regulatory organs of glucose homeostasis that involves multiple gut hormones and microbiota. Notably, the incretin hormone glucagon-like peptide-1 (GLP-1) secreted from enteroendocrine L-cells plays a pivotal role in maintaining glucose homeostasis via eliciting pleiotropic effects, which are largely mediated via its receptor. Thus, targeting the GLP-1 signaling system is a highly attractive therapeutic strategy to treatment T2D. Polyphenols, the secondary metabolites from plants, have drawn considerable attention because of their numerous health benefits, including potential anti-diabetic effects. Although the major targets and locations for the polyphenolic compounds to exert the anti-diabetic action are still unclear, the first organ that is exposed to these compounds is the GI tract in which polyphenols could modulate enzymes and hormones. Indeed, emerging evidence has shown that polyphenols can stimulate GLP-1 secretion, indicating that these natural compounds might exert metabolic action at least partially mediated by GLP-1. This review provides an overview of nutritional regulation of GLP-1 secretion and summarizes recent studies on the roles of polyphenols in GLP-1 secretion and degradation as it relates to metabolic homeostasis. In addition, the effects of polyphenols on microbiota and microbial metabolites that could indirectly modulate GLP-1 secretion are also discussed.

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