PREDICTIONS OF THE EFFECTIVENESS OF INTRAPOPULATION SELECTION VERSUS SELECTION FOR SPECIFIC COMBINING ABILITY IN SWINE

1984 ◽  
Vol 64 (4) ◽  
pp. 799-806
Author(s):  
R. M. McKAY ◽  
G. W. RAHNEFELD
Keyword(s):  
Combining Ability ◽  
Genetic Variance ◽  
Additive Genetic Variance ◽  
Effective Means ◽  
Average Daily Gain ◽  
Mass Selection ◽  
Genetic Covariance ◽  
Selection For ◽  
Sib Selection ◽  
Daily Gain

Additive genetic variance estimates for purebred (Lacombe) and crossbred (Lacombe × Yorkshire) populations and the additive genetic covariance between purebred and crossbred progeny were calculated for postweaning average daily gain, total probe fat, total carcass fat, and litter size in swine. These estimates were used to predict the effectiveness of four methods of intrapopulation selection (IP) relative to selection for specific combining ability (SCA) to determine the most effective means of improving crossbred performance. The intrapopulation methods were mass selection based on information from both sexes (BS), mass selection based on information from one sex (OS), full-sib selection (FS), and half-sib selection (HS). The Lacombe population was selected over 12 generations for increased postweaning average daily gain and the Lacombe × Yorkshire population was generated by breeding Lacombe boars with randomly selected gilts from a Yorkshire control population. Selection for combining ability was the most effective means of improving average daily gain except when information was available on both sexes and the relative selection intensity (SCA/IP) was less than 0.60. Mass selection was superior to SCA for improving total probe fat except when information was restricted to one sex and the relative selection intensity was less than 0.47. For total probe fat and total carcass fat, SCA was superior to FS and HS for relative selection intensities less than 0.65 and 0.74, respectively. Selection for combining ability was superior to OS for litter size regardless of the generation interval length. Key words: Intrapopulation selection, selection for combining ability, additive genetic variance, additive genetic covariance, swine

scholarly journals MASS SELECTION FOR POST-WEANING GROWTH IN SWINE: II. RESPONSE TO SELECTION

1971 ◽  
Vol 51 (2) ◽  
pp. 497-502 ◽  
Author(s):  
G. W. RAHNEFELD
Keyword(s):  
Genetic Variance ◽  
Additive Genetic Variance ◽  
Average Daily Gain ◽  
Mass Selection ◽  
Realized Heritability ◽  
Response To Selection ◽  
Components Of Variance ◽  
Selection For ◽  
Seven Generations ◽  
Daily Gain

Recurrent mass selection for post-weaning average daily gain was practiced for seven generations in a population of Lacombe swine. Response to selection was positive, but the observed response was estimated to be only 0.33 of the predicted. The pooled estimate of additive genetic variance was 0.0013 ± 0.0002. Realized heritability was 0.126 ± 0.029. The pooled estimate of heritability obtained from components of variance and parent-offspring regression was 0.377 ± 0.058. Litter size was positively correlated with average daily gain (0.14 piglet per generation). No significant effects of selection in reducing additive genetic variance were observed.

MASS SELECTION FOR POST-WEANING GROWTH IN SWINE. IV. SELECTION RESPONSE AND CONTROL POPULATION STABILITY

1976 ◽  
Vol 56 (4) ◽  
pp. 783-790
Author(s):  
G. W. RAHNEFELD ◽  
I. GARNETT
Keyword(s):  
Additive Genetic Variance ◽  
Average Daily Gain ◽  
Selection Response ◽  
Relative Magnitude ◽  
Control Population ◽  
Mass Selection ◽  
Gene Effects ◽  
Selection For ◽  
And Control ◽  
Daily Gain

Recurrent mass selection for post-weaning average daily gain was practiced for 11 generations in a population of Lacombe swine. Response to selection was assessed from predicted response, 0.241 ± 0.023 kg; observed response, 0.146 ± 0.018 kg; estimated heritability, 0.327 ± 0.031; and realized heritability, 0.198 ± 0.016. Observed response was estimated to be 0.61 of the predicted. Examination of additive genetic variance, selection differentials, drift variance, inbreeding and regression of post-weaning average daily gain on generation time indicated that the pedigreed Yorkshire control population served as an adequate control. Gene effects were not found to be dependent on the sex of the organism as assessed by the genetic correlation between sexes, covariance between half-sib family means and the relative magnitude of parent–offspring-based estimates of heritability.

MASS SELECTION FOR POST-WEANING GROWTH IN SWINE. V. CORRELATED RESPONSE OF REPRODUCTIVE TRAITS AND PRE-WEANING GROWTH

1976 ◽  
Vol 56 (4) ◽  
pp. 791-801
Author(s):  
I. GARNETT ◽  
G. W. RAHNEFELD
Keyword(s):  
Birth Weight ◽  
Average Daily Gain ◽  
Reproductive Traits ◽  
Correlated Response ◽  
Mass Selection ◽  
Gestation Length ◽  
Control Line ◽  
Weaning Weight ◽  
Selection For ◽  
Daily Gain

Female reproductive performance and pre-weaning survival and growth were examined in a population of swine over 11 generations of selection for post-weaning average daily gain (ADG). Three separate breeding groups were used: (1) a Lacombe (L) line selected each generation for ADG, (2) a Yorkshire control (Y) line, and (3) a crossbred Lacombe × Yorkshire group (LY) generated each generation from the L and Y lines. Breeding group differences were evident for litter size, perinatal mortality, pre-weaning mortality, gestation length, birth weight, pre-weaning average daily gain (PreADG) and weaning weight. Selection did not affect number born, number born alive, number weaned or birth weight. When the values for the L line were expressed as a deviation from the control, pre-weaning mortality showed an increase. The increase appeared to be due to a decrease in the control rather than an increase in the L line. Gestation length showed a negative response to selection. As in the case of pre-weaning mortality, the response appeared to be a reflection of the instability of the control line. Genetic gains in PreADG of 0.004 kg/day/generation were realized in both the L line and LY group. Correspondingly, responses of 0.18 and 0.19 kg/generation were realized for weaning weight in the L line and LY group.

MASS SELECTION FOR POSTWEANING GROWTH IN SWINE. III. CORRELATED RESPONSE IN WEANING WEIGHT AND FEED EFFICIENCY TO RECURRENT SELECTION FOR POSTWEANING AVERAGE DAILY GAIN IN SWINE

1973 ◽  
Vol 53 (2) ◽  
pp. 173-178
Author(s):  
G. W. RAHNEFELD
Keyword(s):  
Genetic Correlation ◽  
Feed Efficiency ◽  
Average Daily Gain ◽  
Direct Selection ◽  
Correlated Response ◽  
Mass Selection ◽  
Total Response ◽  
Weaning Weight ◽  
Selection For ◽  
Daily Gain

Correlated response in weaning weight and feed efficiency were estimated for a genetically variable population of swine selected during nine generations for postweaning average daily gain. Total response in weaning weight to direct selection for gain was 0.03 kg per generation. This was 3.1% of the predicted response. The estimate of genetic correlation between postweaning average daily gain and weaning weight was found high and positive (> 1). Total response in feed efficiency to direct selection for gain was −0.58 kg per generation. This was 10% of the predicted response. The estimate of genetic correlation between postweaning gain and feed efficiency was −0.35.

Adaptability in tropical beef cattle: genetic parameters of growth, adaptive and temperament traits in a crossbred population

2005 ◽  
Vol 45 (8) ◽  
pp. 971 ◽  
Author(s):  
K. C. Prayaga ◽  
J. M. Henshall
Keyword(s):  
Beef Cattle ◽  
Genetic Parameters ◽  
Genetic Variance ◽  
Growth Traits ◽  
Additive Genetic Variance ◽  
Average Daily Gain ◽  
Genetic Correlations ◽  
Temperament Traits ◽  
Indicator Traits ◽  
Daily Gain

Adaptability in tropical beef cattle can be assessed by measurable traits such as growth under the influence of environmental stressors, by parasite resistance as measured by indicator traits such as tick counts (TICK) and faecal egg counts of worms (EPG), by heat resistance as measured by indicator traits such as rectal temperatures (TEMP) and coat scores (COAT) and, to a certain extent, temperament of the animal as measured by flight time (FT). Data from a crossbreeding experiment involving various genotypes derived from tropically adapted British, Sanga-derived, Zebu cross, Zebu and Continental beef cattle breeds were analysed to estimate variance components and genetic parameters of growth, adaptive and temperament traits. Breed group differences were accounted for by including fractional coefficients of direct and maternal additive and dominance genetic effects as covariates. In the univariate analyses, 6 models were compared ranging from the simplest model with animal as the only random effect to the full model comprising direct and maternal additive genetic variance and their covariance and the permanent environment effect due to dam (growth traits) and animal (adaptive and temperament traits). The heritability estimates were 0.41, 0.21, 0.19, 0.28, 0.41 and 0.15 for birth weight (BWT), weaning weight (WWT), preweaning average daily gain (PREADG), yearling weight (YWT), final weight at about 18 months of age (FWT) and post-weaning average daily gain (POADG), respectively. The maternal component of additive genetic variance as a proportion of phenotypic variance in BWT, WWT and PREADG was 0.15, 0.10 and 0.10, respectively. The heritability estimates for TICK, EPG, TEMP, COAT and FT were 0.13, 0.24, 0.12, 0.26 and 0.20, respectively. High positive genetic and phenotypic correlations were observed among growth traits. Low (insignificant) genetic correlations were observed between TICK, EPG and growth traits. However, genetic correlations between growth traits and heat tolerance traits (TEMP and COAT) were moderately negative implying that as the ability of an animal to handle heat stress increases, growth also increases at the genetic level. Genetic correlations among TICK, EPG and TEMP were moderately positive, suggesting that closely-linked genes affect these adaptive traits. The significant negative genetic relationship between TEMP and FT suggests that cattle with high heat resistance have desirable temperament. With the increasing crossbred populations in the northern Australian beef cattle industry, the best breeding strategy should aim to exploit both crossbreeding and within population selection to make improvements in growth, adaptive and temperament traits to increase overall productivity of the enterprise.

MASS SELECTION FOR POSTWEANING GROWTH IN SWINE. VI. MEANS, HERITABILITIES, GENETIC AND PHENOTYPIC CORRELATIONS, AND CORRELATED RESPONSE OF CARCASS TRAITS

1983 ◽  
Vol 63 (1) ◽  
pp. 49-58 ◽  
Author(s):  
G. W. RAHNEFELD ◽  
R. L. CLIPLEF ◽  
I. GARNETT ◽  
R. M. McKAY
Keyword(s):  
Average Daily Gain ◽  
Carcass Traits ◽  
Correlated Response ◽  
Mass Selection ◽  
Correlated Responses ◽  
Phenotypic Correlations ◽  
Genetic And Phenotypic Correlations ◽  
Selection For ◽  
Color Score ◽  
Daily Gain

Means, heritabilities, genetic and phenotypic correlations, and correlated responses in carcass traits (total carcass backfat, carcass length, area 1. dorsi, ham weight, percentage ham of side, percentage lean in ham face, color score, texture score, and marbling score) during 11 generations of selection for postweaning average daily gain were studied on a selected Lacombe line, a Yorkshire control line, and a crossbred Lacombe × Yorkshire group generated each year from the two lines. With the exception of color score, the heritability estimates were moderate to high. Genetic and phenotypic correlations between average daily gain and the carcass traits ranged from − 0.16 to 0.46 and from − 0.07 to 0.15, respectively. Correlated responses in the carcass traits were very small. Key words: Swine, carcass traits, selection, heritabilities, correlations

scholarly journals SELECTION FOR BLOOD PRESSURE LEVELS IN MICE

Genetics ◽  
1974 ◽  
Vol 76 (3) ◽  
pp. 537-549
Author(s):  
Gunther Schlager
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Genetic Variance ◽  
Additive Genetic Variance ◽  
Population Bottleneck ◽  
Control Line ◽  
Selected Lines ◽  
High Line ◽  
Selection For ◽  
Random Control

ABSTRACT Response to two-way selection for systolic blood pressure was immediate and continuous for about eight generations. In the twelfth generation, the High males differed from the Low males by 38 mmHG; the females differed by 39 mmHg. There was little overlap between the two lines and they were statistically significant from each other and from the Random control line. There appeared to be no more additive genetic variance in the eleventh and twelfth generations. Causes for the cessation of response are explored. This is probably due to a combination of natural selection acting to reduce litter sizes in the Low line, a higher incidence of sudden deaths in the High line, and loss of favorable alleles as both selection lines went through a population bottleneck in the ninth generation.—In the eleventh generation, the selected lines were used to produce F1, F2, and backcross generations. A genetic analysis yielded significant additive and dominance components in the inheritance of systolic blood pressure.

scholarly journals The Impact of Selection using Residual Average Daily Gain and Marbling EPDs on Growth Performance and Carcass Traits in Angus Steers

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
T. R. Krause ◽  
E. R. Moore ◽  
J. Duggin ◽  
J. R. Segers ◽  
T. D. Pringle
Keyword(s):  
Growth Performance ◽  
Feed Efficiency ◽  
Average Daily Gain ◽  
Backfat Thickness ◽  
Feeding Trial ◽  
Body Weights ◽  
Selection For ◽  
Carcass Merit ◽  
The Impact ◽  
Daily Gain

ObjectivesProfitability in the beef industry has narrow margins regulated by revenue from output traits like growth and carcass merit, but profitability is also largely impacted by input expenses like feed costs. Selecting for improvements in feed efficiency during the finishing phase, one of the most feed intensive segments of the industry, can help to mitigate those input costs. This study compared growth performance, feed efficiency, body composition, and carcass characteristics in Angus steers (n = 321) from bulls divergently selected for feed efficiency and marbling.Materials and MethodsAngus sires were selected based on high (10th percentile or better) and low (85th percentile or worse) residual average daily gain (RADG) EPD as well as high (fifth percentile or better) and average (near 50th percentile) marbling (MARB) EPD. These criteria resulted in a 2 × 2 factorial design with four breeding lines: high RADG/high MARB, high RADG/average MARB, low RADG/high MARB, low RADG/average MARB. Data were analyzed using MIXED procedures of SAS with RADG and MARB as main effects. Significance was set at α = 0.05. Generation was also analyzed, where generation one (GEN1) steers were from a selected sire while generation two (GEN2) steers were from a selected sire and a selected dam.ResultsUltrasound and carcass data revealed no differences (P ≥ 0.12) in 12th rib backfat thickness from weaning through slaughter for the RADG EPD groups. Yield grade and dressing percent did not differ (P ≥ 0.56) across RADG or MARB groups. At the beginning and end of the feeding trial, the high RADG (P ≤ 0.02) group had larger ultrasound ribeye area (REA) than the low RADG group. Carcass REA tended (P = 0.08) to be larger in the high versus low RADG steers. During the feedlot trial and through slaughter, body weight was heavier (P ≤ 0.006) for the high versus low RADG steers but did not differ (P ≥ 0.44) across MARB EPD. Feed efficiency measures did not differ (P ≥ 0.32) across RADG or MARB groups apart from the tendency (P = 0.08) for residual feed intake to be lower in the high versus low RADG steers. Marbling scores differed (P ≤ 0.04) across RADG and MARB groups with the low RADG steers and the high MARB steers having improved marbling. The quality grade distribution across MARB EPD revealed that the average MARB steers graded 73% Choice and 25% Prime while the high MARB steers graded 56% and 42%, respectively. Slice shear force did not differ (P ≥ 0.32) across RADG or MARB EPD. Body weights tended (P = 0.06) to be heavier at the start of the feeding trial for GEN1 versus GEN2 steers. Total gain, average daily gain, and feed to gain (F:G) differed by generation (P ≤ 0.007) with increased rates of gain and reduced F:G in the GEN2 versus GEN1 steers. Body weights did not differ (P = 0.72) across GEN at the end of the feeding trial. Backfat thickness at the start and end of the feedlot phase was less (P ≤ 0.03) and marbling score was improved (P = 0.02) in the GEN2 versus GEN1 steers, respectively.ConclusionThese results suggest that selection using RADG EPD has negligible impacts on meat quality; and that progress in selection for efficiency can be achieved while advancing carcass quality and value. Furthermore, continued divergent selection for feed efficiency and marbling has the potential to improve feed efficiency through advancements in the rate of gain, while enhancing carcass merit through marbling.

scholarly journals Genetic variance in fitness and its cross-sex covariance predict adaptation during experimental evolution

2020 ◽  
Author(s):  
Eva L. Koch ◽  
Sonja H. Sbilordo ◽  
Frédéric Guillaume
Keyword(s):  
Experimental Evolution ◽  
Genetic Variance ◽  
Environmental Changes ◽  
Additive Genetic Variance ◽  
Relative Fitness ◽  
Male Fitness ◽  
Adaptive Potential ◽  
Genetic Covariance ◽  
Flour Beetles ◽  
Single Stress

AbstractIn presence of rapid environmental changes, it is of particular importance to assess the adaptive potential of populations, which is mostly determined by the additive genetic variation (VA) in fitness. In this study we used Tribolium castaneum (red flour beetles) to investigate its adaptive potential in three new environmental conditions (Dry, Hot, Hot-Dry). We tested for potential constraints that might limit adaptation, including negative genetic covariance between female and male fitness. Based on VA estimates for fitness, we expected the highest relative fitness increase in the most stressful condition Hot-Dry and similar increases in single stress conditions Dry and Hot. High adaptive potential in females in Hot was reduced by a negative covariance with male fitness. We tested adaptation to the three conditions after 20 generations of experimental evolution and found that observed adaptation mainly matched our predictions. Given that body size is commonly used as a proxy for fitness, we also tested how this trait and its genetic variance (including non-additive genetic variance) were impacted by environmental stress. In both traits, variances were sex and condition dependent, but they differed in their variance composition, cross-sex and cross-environment genetic covariances, as well as in the environmental impact on VA.

scholarly journals Effect of the Source of Zinc on the Tissue Accumulation of Zinc and Jejunal Mucosal Zinc Transporter Expression in Holstein Dairy Calves

Animals ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1246 ◽  
Author(s):  
Fengtao Ma ◽  
Yeqianli Wo ◽  
Hongyang Li ◽  
Meinan Chang ◽  
Jingya Wei ◽  
...  
Keyword(s):  
Serum Alkaline Phosphatase ◽  
Effective Means ◽  
Average Daily Gain ◽  
Dairy Calves ◽  
Jejunal Mucosa ◽  
Serum Alkaline Phosphatase Activity ◽  
Zinc Accumulation ◽  
Zinc Concentrations ◽  
Daily Gain ◽  
Transporter Expression

Zinc is considered to be an anti-diarrheal agent, and it may therefore reduce the incidence of diarrhea in young calves. In the present study, we aimed to compare the effect of zinc source on growth performance, the incidence of diarrhea, tissue zinc accumulation, the expression of zinc transporters, and the serum concentrations of zinc-dependent proteins in neonatal Holstein dairy calves. Eighteen male newborn Holstein dairy calves were fed milk and starter diet supplemented with or without 80 mg zinc/d in the form of Zn-Met or ZnO for 14 days, and were then euthanized. Zn-Met supplementation improved average daily gain and feed efficiency, and reduced the incidence of diarrhea, compared with control calves (p < 0.05). It also increased the serum and hepatic zinc concentrations and the mRNA expression of the ZIP4 transporter in the jejunal mucosa of the calves (p < 0.05). In addition, the serum alkaline phosphatase activity and metallothionein concentration were higher in Zn-Met-treated calves than in control calves (p < 0.05). ZnO supplementation had similar effects, but these did not reach significance. Thus, Zn-Met supplementation is an effective means of increasing tissue zinc accumulation and jejunal zinc absorption, and can be used as an anti-diarrheal strategy in neonatal calves.

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