INDUCTION OF CYCLIC ACTIVITY IN THE EARLY POSTPARTUM DAIRY COW
Twenty-five lactating dairy cows were treated with either saline (control), 500 μg gonadotropin-releasing hormone (GnRH), GnRH + 10 mg estradiol 17β (E2), E2, or GnRH + E2 + 25 mg prostaglandin F2α (PGF2α) at approximately 11 days postpartum. Blood samples were taken at the time of injection and then twice each week for about 30 days. Treatment with GnRH alone gave the largest LH peak; LH production appeared to be inhibited when E2 was given with GnRH. Plasma estrogen concentrations were above 1 ng/ml for 12 h in all animals receiving estrogen alone or in combination. None of the treatments hastened initiation of cyclic activity which began at an average of 19 days postpartum. It seems unlikely that postpartum anestrus is an important constraint to early rebreeding in dairy cows.