scholarly journals GENETIC RESISTANCE AND SUSCEPTIBILITY TO MAREK’S DISEASE

1970 ◽  
Vol 50 (1) ◽  
pp. 69-81 ◽  
Author(s):  
J. R. MORRIS ◽  
A. E. FERGUSON ◽  
F. N. JEROME
Keyword(s):  
Genetic Resistance ◽  
Small Population ◽  
Marek's Disease ◽  
Marek’S Disease ◽  
Base Population ◽  
Population Selection ◽  
Two Generations ◽  
Selection For ◽  
Successive Generations ◽  
Single Comb

Three thousand three hundred and thirty-five sire-pedigreed chicks from two commercial lines of Single Comb White Leghorns were inoculated with the Marek’s disease (MD) agent at one day of age and tested over a seven-week period for MD infection. Significant differences were observed between sexes and between lines with respect to MD mortality and total MD incidence. The females were more susceptible. Sire families in both lines showed heterogeneity in their ability to resist MD infection.A second experiment involving selection for resistance and for susceptibility to the disease was conducted on a population of University of Guelph Columbian Plymouth Rocks. Fully pedigreed chicks from this stock were inoculated and reared for 11 weeks while their full-sibs were reared separately to produce subsequent generations of selected families. Two successive generations of selection resulted in the formation of the resistant (R) and susceptible (S) lines. A random sample of the base population was propagated as a control population. Selection for MD resistance resulted in relatively greater progress than selection for MD susceptibility. After two generations of selection there was 12.5%, 54.1% and 61.9% MD mortality and 58.3%, 89.1% and 96.2% total MD incidence in the R, control and S lines, respectively. The more resistant the strain, the longer was the latent period before death. The variability between sexes and between half-sibs declined as MD mortality and total MD incidence approached high and low extremes. The results of the selection imposed showed progress despite the small population under test.

ESTIMASI NILAI HERITABILITAS BOBOT IKAN MAS VARIETAS PUNTEN DALAM PROGRAM SELEKSI INDIVIDU

2016 ◽  
Vol 11 (3) ◽  
pp. 217
Author(s):  
Estu Nugroho ◽  
Budi Setyono ◽  
Mochammad Su’eb ◽  
Tri Heru Prihadi
Keyword(s):  
Body Weight ◽  
Selection Response ◽  
Base Population ◽  
Breeding Programs ◽  
Male And Female ◽  
Body Weight Trait ◽  
Population Selection ◽  
Selection For ◽  
Weight Trait ◽  
Selection Of

Program pemuliaan ikan mas varietas Punten dilakukan dengan seleksi individu terhadap karakter bobot ikan. Pembentukan populasi dasar untuk kegiatan seleksi dilakukan dengan memijahkan secara massal induk ikan mas yang terdiri atas 20 induk betina dan 21 induk jantan yang dikoleksi dari daerah Punten, Kepanjen (delapan betina dan enam jantan), Kediri (tujuh betina dan 12 jantan), Sragen (27 betina dan 10 jantan), dan Blitar (15 betina dan 11 jantan). Larva umur 10 hari dipelihara selama empat bulan. Selanjutnya dilakukan penjarangan sebesar 50% dan benih dipelihara selama 14 bulan untuk dilakukan seleksi dengan panduan hasil sampling 250 ekor individu setiap populasi. Seleksi terhadap calon induk dilakukan saat umur 18 bulan pada populasi jantan dan betina secara terpisah dengan memilih berdasarkan 10% bobot ikan yang terbaik. Calon induk yang terseleksi kemudian dipelihara hingga matang gonad, kemudian dipilih sebanyak 150 pasang dan dipijahkan secara massal. Didapatkan respons positif dari hasil seleksi berdasarkan bobot ikan, yaitu 49,89 g atau 3,66% (populasi ikan jantan) dan 168,47 g atau 11,43% (populasi ikan betina). Nilai heritabilitas untuk bobot ikan adalah 0,238 (jantan) dan 0,505 (betina).Punten carp breeding programs were carried out by individual selection for body weight trait. The base population for selection activities were conducted by mass breeding of parent consisted of 20 female and 21 male collected from area Punten, eight female and six male (Kepanjen), seven female and 12 male (Kediri), 27 female and 10 male (Sragen), 15 female and 11 male (Blitar). Larvae 10 days old reared for four moths. Then after spacing out 50% of total harvest, the offspring reared for 14 months for selection activity based on the sampling of 250 individual each population. Selection of broodstock candidates performed since 18 months age on male and female populations separately by selecting based on 10% of fish with best body weight. Candidates selected broodstocks were then maintained until mature. In oder to produce the next generation 150 pairs were sets and held for mass spawning. The results revealed that selection response were positive, 49.89 g (3.66%) for male and 168.47 (11.43%) for female. Heritability for body weight is 0.238 (male) and 0.505 (female).

Genetic resistance to two Marek's disease viruses and its relationship to production traits in chickens

1992 ◽  
Vol 72 (2) ◽  
pp. 213-225 ◽  
Author(s):  
H. Ameli ◽  
J. S. Gavora ◽  
R. W. Fairfull ◽  
J. L. Spencer
Keyword(s):  
Egg Production ◽  
Genetic Correlations ◽  
Genetic Resistance ◽  
Total Mortality ◽  
Marek's Disease ◽  
Production Test ◽  
Production Traits ◽  
Marek’S Disease ◽  
Genetic Groups ◽  
Challenge Tests

Genetic variability of resistance to Marek's Disease (MD), and relationships between MD incidence and egg production traits were studied in 23 genetic groups of experimental and commercial meat and egg chickens. In the challenge tests, chickens were injected with either moderately virulent BC-1 MD virus (BC-1) or highly virulent RB-1B MD virus (RB-1B). In the 497-d egg-production test, sisters of challenged birds were vaccinated for MD on the day of hatch and there were no outbreaks of MD. Heritabilities for MD incidence, MD mortality, and total mortality in the challenge tests, based on data from three unselected control strains of Leghorns were generally low (0.06, 0.13 and 0.20) with BC-1. With RB-1B, the heritability estimates were significantly (P <.05) higher (0.62, 1.00 and 0.96). Intraclass correlations, based on variation between and within the genetic groups were also higher with RB-1B. In the test with BC-1 there were deaths from an early mortality syndrome (EMS) prior to development of MD. Losses from EMS in Leghorns were highest in 2 genetic groups most resistant to MD. Based on genetic group means, correlations between MD incidence and egg production and egg weight were high and negative. In contrast the correlations between MD incidence, age at first egg, total blood spots, and egg specific gravity tended to be positive. No consistent relationships were found with adult body weight. Key words: Marek's disease, genetic resistance, heritability, genetic correlations, production traits, chickens

Host genetic resistance to Marek's disease sustains protective efficacy of herpesvirus of turkey in both experimental and commercial lines of chickens

Vaccine ◽  
2014 ◽  
Vol 32 (16) ◽  
pp. 1820-1827 ◽  
Author(s):  
Shuang Chang ◽  
Qingmei Xie ◽  
John R. Dunn ◽  
Catherine W. Ernst ◽  
Jiuzhou Song ◽  
...  
Keyword(s):  
Protective Efficacy ◽  
Genetic Resistance ◽  
Marek's Disease ◽  
Marek’S Disease ◽  
Host Genetic

Validation of Alternative Transcript Splicing in Chicken Lines that Differ in Genetic Resistance to Marek’s Disease

2016 ◽  
Vol 27 (4) ◽  
pp. 238-244 ◽  
Author(s):  
Muhammet Kaya ◽  
Likit Preeyanon ◽  
Jerry B. Dodgson ◽  
Hans H. Cheng
Keyword(s):  
Genetic Resistance ◽  
Marek's Disease ◽  
Alternative Transcript ◽  
Marek’S Disease

Selection for Resistance to Marek's Disease and Its Expected Effects on Other Important Traits in White Leghorn Strain Crosses

1972 ◽  
Vol 16 (1) ◽  
pp. 11 ◽  
Author(s):  
C. M. von Krosigk ◽  
C. F. McClary ◽  
E. Vielitz ◽  
D. V. Zander
Keyword(s):  
Marek's Disease ◽  
Marek’S Disease ◽  
White Leghorn ◽  
Selection For
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