Do windbreaks minimize stress on cattle grazing foothill winter range?

2000 ◽  
Vol 80 (2) ◽  
pp. 265-272 ◽  
Author(s):  
B. E. Olson ◽  
R. T. Wallander ◽  
J. A. Paterson

Cattle often graze foothill rangelands in northern latitudes as a cost-effective alternative to being fed hay. In a 2-yr study, we determined whether exposure to winter wind elicits a stress response in pregnant cows (5–7 yr old) grazing a foothill rangeland. We measured several indicators of stress-response of cows which had (windbreak) or did not have (non-windbreak) access to windbreaks. In Winter 1 (1966–1997), backfat thickness increased on windbreak and non-wind-break cattle. Body condition scores of both groups were lower at the end of the trial. In Winter 2 (1997–1998), backfat thickness decreased for windbreak and non-windbreak cattle. Body condition scores did not change. Weight changes were minor both winters. Changes in backfat thickness indicated that cattle in Winter 1 were catabolizing more lean muscle tissue, whereas cattle in Winter 2 were catabolizing more fat. Cattle entered Winter 1 in lower body condition and mass than in Winter 2. Cattle with access to windbreaks tended to have a stronger cell-mediated immune response than non-windbreak cattle. Birth and weaning weights of calves, and calving interval were similar for windbreak and non-windbreak cattle. Neither winter elicited a strong stress response from cattle grazing this foothill rangeland, with or without access to windbreaks. Key words: Beef cattle, backfat, body condition, weight loss, immune response

Author(s):  
Rahul N. Jaiswal ◽  
Anil P. Gosavi ◽  
Ravindranath B. Chavan ◽  
Darshana R. Kundale

<p class="abstract"><strong>Background:</strong> Viral warts are benign proliferation of the skin and mucosa caused by various strains of double stranded DNA human papilloma virus (HPV). MMR immunotherapy of warts is a novel, simple, cost-effective procedure which treats wart by stimulation of non-specific cell mediated immune response to clear HPV virus from the skin. A study to evaluate the role of intralesional measles mumps rubella (MMR) immunotherapy in cutaneous viral warts.</p><p class="abstract"><strong>Methods:</strong> Total 22 patients of both sexes were included in the study. Intralesional MMR 1 unit (0.1 ml) was injected into the largest wart at 2 weeks interval for a maximum of six treatments. Maximum dose of immunotherapy was 0.5 ml for one session and follow up was kept for 3 months duration.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 22, 20 patients completed the treatment, 12 patients (60%) shows complete response, 5 patients (25%) shows partial response and 3 patients (15%) shows no response.</p><p class="abstract"><strong>Conclusions:</strong> Intralesional measles mumps rubella (MMR) immunotherapy is an easy, simple, minimally invasive and relatively painless technique, which helps in induction of an adequate immune response leading to resolution of warts.</p>


2016 ◽  
Vol 94 (suppl_1) ◽  
pp. 71-71
Author(s):  
K. C. Garrett ◽  
D. A. Neuendorff ◽  
A. W. Lewis ◽  
S. T. Willard ◽  
T. H. Welsh ◽  
...  

Viruses ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1457
Author(s):  
Dewald Schoeman ◽  
Burtram C. Fielding

Over the past 18 years, three highly pathogenic human (h) coronaviruses (CoVs) have caused severe outbreaks, the most recent causative agent, SARS-CoV-2, being the first to cause a pandemic. Although much progress has been made since the COVID-19 pandemic started, much about SARS-CoV-2 and its disease, COVID-19, is still poorly understood. The highly pathogenic hCoVs differ in some respects, but also share some similarities in clinical presentation, the risk factors associated with severe disease, and the characteristic immunopathology associated with the progression to severe disease. This review aims to highlight these overlapping aspects of the highly pathogenic hCoVs—SARS-CoV, MERS-CoV, and SARS-CoV-2—briefly discussing the importance of an appropriately regulated immune response; how the immune response to these highly pathogenic hCoVs might be dysregulated through interferon (IFN) inhibition, antibody-dependent enhancement (ADE), and long non-coding RNA (lncRNA); and how these could link to the ensuing cytokine storm. The treatment approaches to highly pathogenic hCoV infections are discussed and it is suggested that a greater focus be placed on T-cell vaccines that elicit a cell-mediated immune response, using rapamycin as a potential agent to improve vaccine responses in the elderly and obese, and the potential of stapled peptides as antiviral agents.


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